ZNF518A

 

Full name: zinc finger protein 518A Alias Symbol: KIAA0335
Type: protein-coding gene Cytoband: 10q24.1
Entrez ID: 9849 HGNC ID: HGNC:29009 Ensembl Gene: ENSG00000177853 OMIM ID: 617733
Drug and gene relationship at DGIdb

 

Expression of ZNF518A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF518A 9849 204291_at -0.2760 0.7019
GSE20347 ZNF518A 9849 204291_at -0.5603 0.0172
GSE23400 ZNF518A 9849 215644_at 0.0284 0.2590
GSE26886 ZNF518A 9849 204291_at -0.6926 0.0503
GSE29001 ZNF518A 9849 204291_at -0.7558 0.0776
GSE38129 ZNF518A 9849 204291_at -0.4698 0.0038
GSE45670 ZNF518A 9849 204291_at -0.0762 0.7525
GSE53622 ZNF518A 9849 4016 -0.4023 0.0009
GSE53624 ZNF518A 9849 9787 -0.1530 0.1275
GSE63941 ZNF518A 9849 204291_at -0.0083 0.9942
GSE77861 ZNF518A 9849 215644_at -0.0662 0.5306
GSE97050 ZNF518A 9849 A_23_P35576 -0.1271 0.7744
SRP007169 ZNF518A 9849 RNAseq 0.5394 0.2724
SRP008496 ZNF518A 9849 RNAseq 0.2541 0.4487
SRP064894 ZNF518A 9849 RNAseq -0.9342 0.0026
SRP133303 ZNF518A 9849 RNAseq -0.6127 0.0001
SRP159526 ZNF518A 9849 RNAseq -0.7345 0.0014
SRP193095 ZNF518A 9849 RNAseq -0.7101 0.0000
SRP219564 ZNF518A 9849 RNAseq -0.6458 0.1342
TCGA ZNF518A 9849 RNAseq -0.2479 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF518A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF518A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF518A 9849 0 8 22
GSE20123 ZNF518A 9849 0 7 23
GSE43470 ZNF518A 9849 0 7 36
GSE46452 ZNF518A 9849 0 11 48
GSE47630 ZNF518A 9849 2 14 24
GSE54993 ZNF518A 9849 7 0 63
GSE54994 ZNF518A 9849 2 10 41
GSE60625 ZNF518A 9849 0 0 11
GSE74703 ZNF518A 9849 0 5 31
GSE74704 ZNF518A 9849 0 4 16
TCGA ZNF518A 9849 5 28 63

Total number of gains: 16; Total number of losses: 94; Total Number of normals: 378.  


 

Somatic mutations of ZNF518A:

 

Generating mutation plots.

 

Highly correlated genes for ZNF518A:

 

Showing top 20/252 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF518AGOT10.817767303
ZNF518APPM1A0.804561303
ZNF518APARG0.798976303
ZNF518ATHRAP30.781714303
ZNF518AZNF5780.776335303
ZNF518ASUCLG10.749732303
ZNF518AECD0.747783303
ZNF518ARABEP20.747023303
ZNF518ACTR90.746197303
ZNF518ASTAM20.743141303
ZNF518ADDX60.731839303
ZNF518AAKIRIN10.729994303
ZNF518ATPRG1L0.729159303
ZNF518APPP2R5E0.728268303
ZNF518APRDM40.727198303
ZNF518AZNF5060.723084404
ZNF518AUSP340.720748303
ZNF518APANK10.713837404
ZNF518ALANCL10.708287303
ZNF518ACUL30.702448403

For details and further investigation, click here