| Full name: recombination activating 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 5897 | HGNC ID: HGNC:9832 | Ensembl Gene: ENSG00000175097 | OMIM ID: 179616 |
| Drug and gene relationship at DGIdb | |||
RAG2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04068 | FoxO signaling pathway |
Expression of RAG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAG2 | 5897 | 215117_at | 0.1527 | 0.4068 | |
| GSE20347 | RAG2 | 5897 | 215117_at | 0.0081 | 0.8688 | |
| GSE23400 | RAG2 | 5897 | 215117_at | -0.0142 | 0.3625 | |
| GSE26886 | RAG2 | 5897 | 215117_at | 0.0066 | 0.9387 | |
| GSE29001 | RAG2 | 5897 | 215117_at | -0.0313 | 0.7652 | |
| GSE38129 | RAG2 | 5897 | 215117_at | -0.0483 | 0.2124 | |
| GSE45670 | RAG2 | 5897 | 215117_at | 0.0983 | 0.0299 | |
| GSE53622 | RAG2 | 5897 | 58756 | 0.0388 | 0.8534 | |
| GSE53624 | RAG2 | 5897 | 58756 | -0.0963 | 0.5811 | |
| GSE63941 | RAG2 | 5897 | 215117_at | 0.0575 | 0.6470 | |
| GSE77861 | RAG2 | 5897 | 215117_at | -0.0206 | 0.7931 | |
| GSE97050 | RAG2 | 5897 | A_33_P3260782 | 0.0666 | 0.7575 | |
| TCGA | RAG2 | 5897 | RNAseq | 0.9523 | 0.6656 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAG2 | 5897 | 0 | 8 | 22 | |
| GSE20123 | RAG2 | 5897 | 0 | 7 | 23 | |
| GSE43470 | RAG2 | 5897 | 3 | 4 | 36 | |
| GSE46452 | RAG2 | 5897 | 7 | 5 | 47 | |
| GSE47630 | RAG2 | 5897 | 3 | 10 | 27 | |
| GSE54993 | RAG2 | 5897 | 3 | 2 | 65 | |
| GSE54994 | RAG2 | 5897 | 3 | 10 | 40 | |
| GSE60625 | RAG2 | 5897 | 0 | 0 | 11 | |
| GSE74703 | RAG2 | 5897 | 2 | 2 | 32 | |
| GSE74704 | RAG2 | 5897 | 0 | 5 | 15 | |
| TCGA | RAG2 | 5897 | 12 | 22 | 62 |
Total number of gains: 33; Total number of losses: 75; Total Number of normals: 380.
Somatic mutations of RAG2:
Generating mutation plots.
Highly correlated genes for RAG2:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAG2 | B3GALT1 | 0.758568 | 3 | 0 | 3 |
| RAG2 | CPNE9 | 0.742434 | 3 | 0 | 3 |
| RAG2 | LAMTOR2 | 0.719959 | 3 | 0 | 3 |
| RAG2 | NPY2R | 0.709125 | 4 | 0 | 3 |
| RAG2 | RELB | 0.701358 | 4 | 0 | 3 |
| RAG2 | SLC38A8 | 0.696755 | 3 | 0 | 3 |
| RAG2 | LTB4R2 | 0.682003 | 3 | 0 | 3 |
| RAG2 | CBX8 | 0.681808 | 3 | 0 | 3 |
| RAG2 | CEBPE | 0.674001 | 4 | 0 | 3 |
| RAG2 | GEMIN2 | 0.670152 | 3 | 0 | 3 |
| RAG2 | GPR17 | 0.668679 | 3 | 0 | 3 |
| RAG2 | PDCL | 0.663295 | 4 | 0 | 3 |
| RAG2 | SNAI1 | 0.652185 | 3 | 0 | 3 |
| RAG2 | MARVELD3 | 0.645824 | 3 | 0 | 3 |
| RAG2 | HNF4A | 0.642486 | 4 | 0 | 3 |
| RAG2 | SBNO2 | 0.642288 | 5 | 0 | 3 |
| RAG2 | DENND1C | 0.63711 | 3 | 0 | 3 |
| RAG2 | CNGB3 | 0.636933 | 4 | 0 | 3 |
| RAG2 | PGC | 0.632053 | 4 | 0 | 3 |
| RAG2 | TP73 | 0.626855 | 4 | 0 | 3 |
For details and further investigation, click here
