| Full name: RNA binding motif protein 12 | Alias Symbol: HRIHFB2091|KIAA0765|SWAN | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 10137 | HGNC ID: HGNC:9898 | Ensembl Gene: ENSG00000244462 | OMIM ID: 607179 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM12 | 10137 | 212168_at | 0.4070 | 0.1587 | |
| GSE20347 | RBM12 | 10137 | 212168_at | 0.4768 | 0.0047 | |
| GSE23400 | RBM12 | 10137 | 212168_at | 0.7039 | 0.0000 | |
| GSE26886 | RBM12 | 10137 | 212168_at | 0.3687 | 0.0912 | |
| GSE29001 | RBM12 | 10137 | 212168_at | 0.4814 | 0.1957 | |
| GSE38129 | RBM12 | 10137 | 212168_at | 0.5427 | 0.0000 | |
| GSE45670 | RBM12 | 10137 | 212168_at | 0.3318 | 0.0049 | |
| GSE53622 | RBM12 | 10137 | 109819 | 0.2731 | 0.0001 | |
| GSE53624 | RBM12 | 10137 | 109819 | 0.1206 | 0.0625 | |
| GSE63941 | RBM12 | 10137 | 212168_at | 0.4868 | 0.0895 | |
| GSE77861 | RBM12 | 10137 | 212168_at | 0.6128 | 0.0026 | |
| GSE97050 | RBM12 | 10137 | A_33_P3416286 | 0.0592 | 0.8150 | |
| SRP007169 | RBM12 | 10137 | RNAseq | 0.2834 | 0.3369 | |
| SRP008496 | RBM12 | 10137 | RNAseq | 0.4623 | 0.0127 | |
| SRP064894 | RBM12 | 10137 | RNAseq | -0.0393 | 0.8212 | |
| SRP133303 | RBM12 | 10137 | RNAseq | 0.2887 | 0.0178 | |
| SRP159526 | RBM12 | 10137 | RNAseq | 0.1141 | 0.5621 | |
| SRP193095 | RBM12 | 10137 | RNAseq | 0.1684 | 0.0259 | |
| SRP219564 | RBM12 | 10137 | RNAseq | -0.0204 | 0.9298 | |
| TCGA | RBM12 | 10137 | RNAseq | 0.0380 | 0.3893 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBM12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM12 | 10137 | 15 | 1 | 14 | |
| GSE20123 | RBM12 | 10137 | 15 | 1 | 14 | |
| GSE43470 | RBM12 | 10137 | 12 | 0 | 31 | |
| GSE46452 | RBM12 | 10137 | 29 | 0 | 30 | |
| GSE47630 | RBM12 | 10137 | 25 | 0 | 15 | |
| GSE54993 | RBM12 | 10137 | 0 | 17 | 53 | |
| GSE54994 | RBM12 | 10137 | 24 | 0 | 29 | |
| GSE60625 | RBM12 | 10137 | 0 | 0 | 11 | |
| GSE74703 | RBM12 | 10137 | 11 | 0 | 25 | |
| GSE74704 | RBM12 | 10137 | 11 | 0 | 9 | |
| TCGA | RBM12 | 10137 | 49 | 3 | 44 |
Total number of gains: 191; Total number of losses: 22; Total Number of normals: 275.
Somatic mutations of RBM12:
Generating mutation plots.
Highly correlated genes for RBM12:
Showing top 20/1579 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM12 | TRUB1 | 0.83822 | 3 | 0 | 3 |
| RBM12 | RIOK1 | 0.746837 | 4 | 0 | 4 |
| RBM12 | HPS3 | 0.745937 | 5 | 0 | 5 |
| RBM12 | RRP36 | 0.740301 | 3 | 0 | 3 |
| RBM12 | NTMT1 | 0.735251 | 3 | 0 | 3 |
| RBM12 | ILF2 | 0.732437 | 10 | 0 | 9 |
| RBM12 | ACSS2 | 0.730004 | 3 | 0 | 3 |
| RBM12 | XXYLT1 | 0.725506 | 3 | 0 | 3 |
| RBM12 | AP1AR | 0.725098 | 4 | 0 | 3 |
| RBM12 | NF1 | 0.716497 | 3 | 0 | 3 |
| RBM12 | IRF2BPL | 0.715417 | 5 | 0 | 5 |
| RBM12 | RAN | 0.709199 | 8 | 0 | 8 |
| RBM12 | SESTD1 | 0.707571 | 3 | 0 | 3 |
| RBM12 | BRMS1L | 0.707142 | 4 | 0 | 3 |
| RBM12 | JAK1 | 0.706808 | 3 | 0 | 3 |
| RBM12 | SRSF12 | 0.706347 | 3 | 0 | 3 |
| RBM12 | SNRPG | 0.704517 | 9 | 0 | 8 |
| RBM12 | MRPS5 | 0.703836 | 3 | 0 | 3 |
| RBM12 | GGNBP2 | 0.701213 | 4 | 0 | 3 |
| RBM12 | DLD | 0.700691 | 4 | 0 | 3 |
For details and further investigation, click here
