RBMS1

 

Full name: RNA binding motif single stranded interacting protein 1 Alias Symbol: SCR2|MSSP-1|MSSP-2|MSSP-3|YC1|HCC-4|DKFZp564H0764
Type: protein-coding gene Cytoband: 2q24.2
Entrez ID: 5937 HGNC ID: HGNC:9907 Ensembl Gene: ENSG00000153250 OMIM ID: 602310
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of RBMS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RBMS1 5937 215127_s_at 0.3516 0.5169
GSE20347 RBMS1 5937 215127_s_at 0.4038 0.0094
GSE23400 RBMS1 5937 203748_x_at 0.0850 0.2200
GSE26886 RBMS1 5937 225265_at -0.4893 0.0537
GSE29001 RBMS1 5937 215127_s_at 0.3198 0.2474
GSE38129 RBMS1 5937 215127_s_at 0.2579 0.0543
GSE45670 RBMS1 5937 215127_s_at -0.0950 0.5582
GSE53622 RBMS1 5937 51956 0.2616 0.0001
GSE53624 RBMS1 5937 51956 0.5466 0.0000
GSE63941 RBMS1 5937 215127_s_at -0.9861 0.0208
GSE77861 RBMS1 5937 215127_s_at 0.5040 0.1023
GSE97050 RBMS1 5937 A_23_P431410 0.0591 0.8066
SRP007169 RBMS1 5937 RNAseq -0.6410 0.1582
SRP008496 RBMS1 5937 RNAseq -0.4452 0.0946
SRP064894 RBMS1 5937 RNAseq 0.1144 0.5620
SRP133303 RBMS1 5937 RNAseq 0.5068 0.0112
SRP159526 RBMS1 5937 RNAseq 0.1892 0.3476
SRP193095 RBMS1 5937 RNAseq 0.1661 0.2393
SRP219564 RBMS1 5937 RNAseq 0.0499 0.9048
TCGA RBMS1 5937 RNAseq 0.1226 0.0135

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RBMS1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RBMS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RBMS1 5937 5 1 24
GSE20123 RBMS1 5937 5 1 24
GSE43470 RBMS1 5937 4 1 38
GSE46452 RBMS1 5937 1 4 54
GSE47630 RBMS1 5937 5 3 32
GSE54993 RBMS1 5937 0 4 66
GSE54994 RBMS1 5937 11 2 40
GSE60625 RBMS1 5937 0 3 8
GSE74703 RBMS1 5937 3 1 32
GSE74704 RBMS1 5937 3 0 17
TCGA RBMS1 5937 23 10 63

Total number of gains: 60; Total number of losses: 30; Total Number of normals: 398.  


 

Somatic mutations of RBMS1:

 

Generating mutation plots.

 

Highly correlated genes for RBMS1:

 

Showing top 20/241 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RBMS1PDHX0.816227303
RBMS1CWC220.782766303
RBMS1CEBPZ0.774852404
RBMS1UBXN2A0.75904303
RBMS1NUP350.751561303
RBMS1DDX590.733328303
RBMS1SREBF10.725745303
RBMS1EXOC80.725332403
RBMS1CCP1100.722875303
RBMS1ZFYVE260.708775303
RBMS1KCTD210.707928303
RBMS1ZNF6380.706151404
RBMS1UBE2K0.685079303
RBMS1ZNF230.675958403
RBMS1SEC16A0.672566303
RBMS1ADAP20.671702303
RBMS1FAF20.66921303
RBMS1DYNC1I20.66753604
RBMS1ANKRD36B0.666824303
RBMS1UBE2E20.666596303

For details and further investigation, click here