| Full name: N-terminal EF-hand calcium binding protein 3 | Alias Symbol: XB51|dJ63M2.4|NIP1|dJ63M2.5|EFCBP3 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 63941 | HGNC ID: HGNC:15851 | Ensembl Gene: ENSG00000125967 | OMIM ID: 612478 |
| Drug and gene relationship at DGIdb | |||
Expression of NECAB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NECAB3 | 63941 | 210720_s_at | 0.5078 | 0.2143 | |
| GSE20347 | NECAB3 | 63941 | 210720_s_at | 0.2212 | 0.1193 | |
| GSE23400 | NECAB3 | 63941 | 210720_s_at | -0.0297 | 0.5728 | |
| GSE26886 | NECAB3 | 63941 | 210720_s_at | 0.6281 | 0.0036 | |
| GSE29001 | NECAB3 | 63941 | 210720_s_at | 0.3761 | 0.0790 | |
| GSE38129 | NECAB3 | 63941 | 210720_s_at | 0.0582 | 0.7035 | |
| GSE45670 | NECAB3 | 63941 | 223954_x_at | 0.2491 | 0.0064 | |
| GSE53622 | NECAB3 | 63941 | 148011 | -0.3613 | 0.0000 | |
| GSE53624 | NECAB3 | 63941 | 148011 | -0.3147 | 0.0000 | |
| GSE63941 | NECAB3 | 63941 | 223954_x_at | 0.6719 | 0.0156 | |
| GSE77861 | NECAB3 | 63941 | 223954_x_at | 0.0479 | 0.7485 | |
| GSE97050 | NECAB3 | 63941 | A_23_P68628 | -0.0712 | 0.8443 | |
| SRP007169 | NECAB3 | 63941 | RNAseq | 0.1969 | 0.6919 | |
| SRP008496 | NECAB3 | 63941 | RNAseq | 0.3205 | 0.2833 | |
| SRP064894 | NECAB3 | 63941 | RNAseq | 0.3827 | 0.1462 | |
| SRP133303 | NECAB3 | 63941 | RNAseq | 0.1162 | 0.5302 | |
| SRP159526 | NECAB3 | 63941 | RNAseq | 0.6367 | 0.1111 | |
| SRP193095 | NECAB3 | 63941 | RNAseq | 0.2379 | 0.1414 | |
| SRP219564 | NECAB3 | 63941 | RNAseq | 0.7179 | 0.2168 | |
| TCGA | NECAB3 | 63941 | RNAseq | -0.4220 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NECAB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NECAB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NECAB3 | 63941 | 15 | 0 | 15 | |
| GSE20123 | NECAB3 | 63941 | 15 | 0 | 15 | |
| GSE43470 | NECAB3 | 63941 | 12 | 0 | 31 | |
| GSE46452 | NECAB3 | 63941 | 29 | 0 | 30 | |
| GSE47630 | NECAB3 | 63941 | 24 | 1 | 15 | |
| GSE54993 | NECAB3 | 63941 | 0 | 19 | 51 | |
| GSE54994 | NECAB3 | 63941 | 25 | 1 | 27 | |
| GSE60625 | NECAB3 | 63941 | 0 | 0 | 11 | |
| GSE74703 | NECAB3 | 63941 | 11 | 0 | 25 | |
| GSE74704 | NECAB3 | 63941 | 10 | 0 | 10 | |
| TCGA | NECAB3 | 63941 | 51 | 1 | 44 |
Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.
Somatic mutations of NECAB3:
Generating mutation plots.
Highly correlated genes for NECAB3:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NECAB3 | FBP1 | 0.744488 | 3 | 0 | 3 |
| NECAB3 | PGP | 0.732748 | 3 | 0 | 3 |
| NECAB3 | REM2 | 0.730288 | 3 | 0 | 3 |
| NECAB3 | RNF216 | 0.716131 | 3 | 0 | 3 |
| NECAB3 | KLK3 | 0.71039 | 3 | 0 | 3 |
| NECAB3 | ACTR3B | 0.70906 | 3 | 0 | 3 |
| NECAB3 | LIME1 | 0.701416 | 4 | 0 | 3 |
| NECAB3 | TMEM179 | 0.700094 | 3 | 0 | 3 |
| NECAB3 | FAM178B | 0.691761 | 3 | 0 | 3 |
| NECAB3 | FLAD1 | 0.685359 | 4 | 0 | 4 |
| NECAB3 | RNF139-AS1 | 0.677246 | 3 | 0 | 3 |
| NECAB3 | E2F1 | 0.677152 | 6 | 0 | 6 |
| NECAB3 | TAF5L | 0.676556 | 4 | 0 | 4 |
| NECAB3 | DPEP3 | 0.674693 | 3 | 0 | 3 |
| NECAB3 | RHBDD3 | 0.673093 | 4 | 0 | 3 |
| NECAB3 | ZNF526 | 0.667458 | 4 | 0 | 3 |
| NECAB3 | SIGLEC7 | 0.666967 | 3 | 0 | 3 |
| NECAB3 | MLF1 | 0.666747 | 3 | 0 | 3 |
| NECAB3 | SPZ1 | 0.663752 | 3 | 0 | 3 |
| NECAB3 | WDR55 | 0.663327 | 3 | 0 | 3 |
For details and further investigation, click here
