RFXANK

 

Full name: regulatory factor X associated ankyrin containing protein Alias Symbol: BLS|RFX-B|ANKRA1|F14150_1|MGC138628
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 8625 HGNC ID: HGNC:9987 Ensembl Gene: ENSG00000064490 OMIM ID: 603200
Drug and gene relationship at DGIdb

 

RFXANK involved pathways:

KEGG pathway Description View
hsa04612Antigen processing and presentation
hsa05152Tuberculosis

 

Expression of RFXANK:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RFXANK 8625 202758_s_at 0.1849 0.6532
GSE20347 RFXANK 8625 202758_s_at -0.0318 0.8645
GSE23400 RFXANK 8625 202758_s_at 0.1716 0.0127
GSE26886 RFXANK 8625 202758_s_at 0.3044 0.2452
GSE29001 RFXANK 8625 202758_s_at 0.0731 0.8788
GSE38129 RFXANK 8625 202758_s_at 0.1891 0.0876
GSE45670 RFXANK 8625 202758_s_at 0.0865 0.6095
GSE53622 RFXANK 8625 66248 0.0516 0.5028
GSE53624 RFXANK 8625 66248 0.2731 0.0000
GSE63941 RFXANK 8625 202758_s_at 1.4642 0.0021
GSE77861 RFXANK 8625 202758_s_at 0.1614 0.4238
GSE97050 RFXANK 8625 A_23_P165180 0.2335 0.4357
SRP007169 RFXANK 8625 RNAseq -0.4671 0.1967
SRP008496 RFXANK 8625 RNAseq -0.4415 0.0596
SRP064894 RFXANK 8625 RNAseq 0.8126 0.0317
SRP133303 RFXANK 8625 RNAseq -0.1486 0.2281
SRP159526 RFXANK 8625 RNAseq 0.0548 0.8193
SRP193095 RFXANK 8625 RNAseq -0.1080 0.3073
SRP219564 RFXANK 8625 RNAseq 0.0625 0.7736
TCGA RFXANK 8625 RNAseq 0.2007 0.0024

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by RFXANK expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RFXANK:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RFXANK 8625 4 5 21
GSE20123 RFXANK 8625 3 3 24
GSE43470 RFXANK 8625 2 5 36
GSE46452 RFXANK 8625 47 1 11
GSE47630 RFXANK 8625 5 8 27
GSE54993 RFXANK 8625 16 4 50
GSE54994 RFXANK 8625 6 13 34
GSE60625 RFXANK 8625 9 0 2
GSE74703 RFXANK 8625 2 3 31
GSE74704 RFXANK 8625 0 3 17
TCGA RFXANK 8625 15 11 70

Total number of gains: 109; Total number of losses: 56; Total Number of normals: 323.  

 

Somatic mutations of RFXANK:

 

Generating mutation plots.

 

Highly correlated genes for RFXANK:

 

Showing top 20/809 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RFXANKFDXACB10.761508303
RFXANKRNFT20.756624303
RFXANKTOP3B0.747612404
RFXANKPRDM150.746343303
RFXANKMRPL380.734093505
RFXANKCNOT100.725711404
RFXANKC2orf760.725291303
RFXANKNADSYN10.724755303
RFXANKZNF1950.720015303
RFXANKECHS10.703755303
RFXANKPLEKHJ10.702286303
RFXANKNACC10.701084403
RFXANKMTCH10.700921303
RFXANKRHNO10.694677303
RFXANKPCGF60.688663303
RFXANKPLEKHM20.686427403
RFXANKNKAP0.679094303
RFXANKMRPL270.679055404
RFXANKCHAMP10.67871303
RFXANKTRIM590.677863303

For details and further investigation, click here