| Full name: NAD synthetase 1 | Alias Symbol: FLJ10631 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 55191 | HGNC ID: HGNC:29832 | Ensembl Gene: ENSG00000172890 | OMIM ID: 608285 |
| Drug and gene relationship at DGIdb | |||
Expression of NADSYN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NADSYN1 | 55191 | 232946_s_at | 0.6900 | 0.3295 | |
| GSE20347 | NADSYN1 | 55191 | 218840_s_at | -0.3079 | 0.3672 | |
| GSE23400 | NADSYN1 | 55191 | 218840_s_at | 0.1312 | 0.3757 | |
| GSE26886 | NADSYN1 | 55191 | 218840_s_at | 0.2405 | 0.5952 | |
| GSE29001 | NADSYN1 | 55191 | 218840_s_at | -0.2197 | 0.7307 | |
| GSE38129 | NADSYN1 | 55191 | 218840_s_at | 0.0365 | 0.9092 | |
| GSE45670 | NADSYN1 | 55191 | 218840_s_at | 0.4184 | 0.1148 | |
| GSE53622 | NADSYN1 | 55191 | 20861 | 0.0221 | 0.8714 | |
| GSE53624 | NADSYN1 | 55191 | 20861 | -0.0248 | 0.7925 | |
| GSE63941 | NADSYN1 | 55191 | 232946_s_at | 0.1542 | 0.8733 | |
| GSE77861 | NADSYN1 | 55191 | 232946_s_at | 0.9375 | 0.2134 | |
| GSE97050 | NADSYN1 | 55191 | A_23_P35848 | 0.3290 | 0.3713 | |
| SRP007169 | NADSYN1 | 55191 | RNAseq | -1.2897 | 0.0004 | |
| SRP008496 | NADSYN1 | 55191 | RNAseq | -1.0481 | 0.0000 | |
| SRP064894 | NADSYN1 | 55191 | RNAseq | 0.0452 | 0.8571 | |
| SRP133303 | NADSYN1 | 55191 | RNAseq | 1.1915 | 0.0011 | |
| SRP159526 | NADSYN1 | 55191 | RNAseq | 1.9303 | 0.0012 | |
| SRP193095 | NADSYN1 | 55191 | RNAseq | 0.1824 | 0.4702 | |
| SRP219564 | NADSYN1 | 55191 | RNAseq | 0.6389 | 0.2990 | |
| TCGA | NADSYN1 | 55191 | RNAseq | 0.1590 | 0.0776 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by NADSYN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NADSYN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NADSYN1 | 55191 | 12 | 6 | 12 | |
| GSE20123 | NADSYN1 | 55191 | 11 | 6 | 13 | |
| GSE43470 | NADSYN1 | 55191 | 7 | 4 | 32 | |
| GSE46452 | NADSYN1 | 55191 | 18 | 12 | 29 | |
| GSE47630 | NADSYN1 | 55191 | 11 | 9 | 20 | |
| GSE54993 | NADSYN1 | 55191 | 4 | 11 | 55 | |
| GSE54994 | NADSYN1 | 55191 | 16 | 12 | 25 | |
| GSE60625 | NADSYN1 | 55191 | 0 | 7 | 4 | |
| GSE74703 | NADSYN1 | 55191 | 6 | 3 | 27 | |
| GSE74704 | NADSYN1 | 55191 | 7 | 4 | 9 | |
| TCGA | NADSYN1 | 55191 | 45 | 15 | 36 |
Total number of gains: 137; Total number of losses: 89; Total Number of normals: 262.
Somatic mutations of NADSYN1:
Generating mutation plots.
Highly correlated genes for NADSYN1:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NADSYN1 | SLC1A5 | 0.810303 | 3 | 0 | 3 |
| NADSYN1 | MRPL51 | 0.779755 | 3 | 0 | 3 |
| NADSYN1 | NACC1 | 0.756236 | 3 | 0 | 3 |
| NADSYN1 | UBE2J2 | 0.741877 | 3 | 0 | 3 |
| NADSYN1 | LTBR | 0.741007 | 3 | 0 | 3 |
| NADSYN1 | RNF187 | 0.734025 | 3 | 0 | 3 |
| NADSYN1 | ALG10 | 0.73371 | 3 | 0 | 3 |
| NADSYN1 | NCAPD2 | 0.731516 | 3 | 0 | 3 |
| NADSYN1 | EMG1 | 0.726324 | 3 | 0 | 3 |
| NADSYN1 | CLSTN1 | 0.725834 | 3 | 0 | 3 |
| NADSYN1 | RFXANK | 0.724755 | 3 | 0 | 3 |
| NADSYN1 | MCM3AP | 0.724721 | 3 | 0 | 3 |
| NADSYN1 | DPM2 | 0.720527 | 3 | 0 | 3 |
| NADSYN1 | ACOT7 | 0.709173 | 3 | 0 | 3 |
| NADSYN1 | NUP62 | 0.704431 | 3 | 0 | 3 |
| NADSYN1 | CD3EAP | 0.701774 | 3 | 0 | 3 |
| NADSYN1 | KIF23 | 0.700641 | 3 | 0 | 3 |
| NADSYN1 | MRPL3 | 0.698845 | 3 | 0 | 3 |
| NADSYN1 | SNRPD3 | 0.698431 | 3 | 0 | 3 |
| NADSYN1 | ASPSCR1 | 0.696923 | 3 | 0 | 3 |
For details and further investigation, click here
