| Full name: Rh blood group D antigen | Alias Symbol: Rh30a|Rh4|RhPI|RhII|DIIIc|CD240D | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 6007 | HGNC ID: HGNC:10009 | Ensembl Gene: ENSG00000187010 | OMIM ID: 111680 |
| Drug and gene relationship at DGIdb | |||
Expression of RHD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHD | 6007 | 210430_x_at | -0.1244 | 0.5831 | |
| GSE20347 | RHD | 6007 | 210430_x_at | -0.0041 | 0.9810 | |
| GSE23400 | RHD | 6007 | 210430_x_at | -0.0427 | 0.3527 | |
| GSE26886 | RHD | 6007 | 210430_x_at | -0.1513 | 0.4993 | |
| GSE29001 | RHD | 6007 | 210430_x_at | -0.1042 | 0.5602 | |
| GSE38129 | RHD | 6007 | 210430_x_at | -0.1614 | 0.1034 | |
| GSE45670 | RHD | 6007 | 210430_x_at | 0.1292 | 0.1977 | |
| GSE53622 | RHD | 6007 | 85539 | -1.0108 | 0.0000 | |
| GSE53624 | RHD | 6007 | 85539 | -1.3370 | 0.0000 | |
| GSE63941 | RHD | 6007 | 210430_x_at | 0.0985 | 0.6669 | |
| GSE77861 | RHD | 6007 | 210430_x_at | 0.0418 | 0.7052 | |
| GSE97050 | RHD | 6007 | A_24_P673333 | -0.0592 | 0.7651 | |
| SRP064894 | RHD | 6007 | RNAseq | -0.0051 | 0.9831 | |
| SRP133303 | RHD | 6007 | RNAseq | -0.1280 | 0.4703 | |
| SRP159526 | RHD | 6007 | RNAseq | -0.0415 | 0.9317 | |
| SRP193095 | RHD | 6007 | RNAseq | -0.0443 | 0.7898 | |
| SRP219564 | RHD | 6007 | RNAseq | -0.1913 | 0.6127 | |
| TCGA | RHD | 6007 | RNAseq | -0.3426 | 0.2599 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RHD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHD | 6007 | 0 | 5 | 25 | |
| GSE20123 | RHD | 6007 | 0 | 4 | 26 | |
| GSE43470 | RHD | 6007 | 2 | 6 | 35 | |
| GSE46452 | RHD | 6007 | 5 | 1 | 53 | |
| GSE47630 | RHD | 6007 | 8 | 3 | 29 | |
| GSE54993 | RHD | 6007 | 2 | 1 | 67 | |
| GSE54994 | RHD | 6007 | 11 | 4 | 38 | |
| GSE60625 | RHD | 6007 | 0 | 0 | 11 | |
| GSE74703 | RHD | 6007 | 1 | 4 | 31 | |
| GSE74704 | RHD | 6007 | 0 | 0 | 20 | |
| TCGA | RHD | 6007 | 10 | 24 | 62 |
Total number of gains: 39; Total number of losses: 52; Total Number of normals: 397.
Somatic mutations of RHD:
Generating mutation plots.
Highly correlated genes for RHD:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHD | SPATA24 | 0.715268 | 3 | 0 | 3 |
| RHD | RECK | 0.684309 | 4 | 0 | 4 |
| RHD | ART1 | 0.6842 | 5 | 0 | 5 |
| RHD | OR12D2 | 0.6752 | 6 | 0 | 6 |
| RHD | FAM135B | 0.674298 | 3 | 0 | 3 |
| RHD | ADRB3 | 0.664214 | 4 | 0 | 4 |
| RHD | SIGLEC6 | 0.660541 | 5 | 0 | 5 |
| RHD | NDST4 | 0.659852 | 3 | 0 | 3 |
| RHD | PAPPA2 | 0.656471 | 6 | 0 | 5 |
| RHD | CRISP1 | 0.656195 | 6 | 0 | 5 |
| RHD | JAK3 | 0.655948 | 4 | 0 | 4 |
| RHD | KDM6A | 0.654372 | 3 | 0 | 3 |
| RHD | EDA2R | 0.65343 | 6 | 0 | 4 |
| RHD | PIK3R5 | 0.652389 | 4 | 0 | 4 |
| RHD | GML | 0.649207 | 6 | 0 | 6 |
| RHD | IFNA17 | 0.643744 | 5 | 0 | 4 |
| RHD | NEU3 | 0.641849 | 5 | 0 | 4 |
| RHD | CHRM5 | 0.640249 | 5 | 0 | 5 |
| RHD | CYP4F2 | 0.634525 | 3 | 0 | 3 |
| RHD | SMPDL3A | 0.631779 | 3 | 0 | 3 |
For details and further investigation, click here
