| Full name: cytochrome P450 family 4 subfamily F member 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 8529 | HGNC ID: HGNC:2645 | Ensembl Gene: ENSG00000186115 | OMIM ID: 604426 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP4F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP4F2 | 8529 | 210452_x_at | -0.8499 | 0.2217 | |
| GSE20347 | CYP4F2 | 8529 | 210452_x_at | -0.0388 | 0.8596 | |
| GSE23400 | CYP4F2 | 8529 | 210452_x_at | -0.1203 | 0.1389 | |
| GSE26886 | CYP4F2 | 8529 | 210452_x_at | -0.4463 | 0.3626 | |
| GSE29001 | CYP4F2 | 8529 | 210452_x_at | -0.4838 | 0.0475 | |
| GSE38129 | CYP4F2 | 8529 | 210452_x_at | 0.0600 | 0.8163 | |
| GSE45670 | CYP4F2 | 8529 | 210452_x_at | 0.0661 | 0.8941 | |
| GSE53622 | CYP4F2 | 8529 | 13761 | -1.2084 | 0.0004 | |
| GSE53624 | CYP4F2 | 8529 | 13761 | -1.5012 | 0.0000 | |
| GSE63941 | CYP4F2 | 8529 | 210452_x_at | 0.9202 | 0.3064 | |
| GSE77861 | CYP4F2 | 8529 | 210452_x_at | -0.1287 | 0.6368 | |
| GSE97050 | CYP4F2 | 8529 | A_23_P50710 | -0.7337 | 0.1421 | |
| SRP133303 | CYP4F2 | 8529 | RNAseq | -0.4610 | 0.1748 | |
| TCGA | CYP4F2 | 8529 | RNAseq | -1.2473 | 0.2409 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CYP4F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP4F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP4F2 | 8529 | 4 | 2 | 24 | |
| GSE20123 | CYP4F2 | 8529 | 3 | 1 | 26 | |
| GSE43470 | CYP4F2 | 8529 | 2 | 6 | 35 | |
| GSE46452 | CYP4F2 | 8529 | 47 | 1 | 11 | |
| GSE47630 | CYP4F2 | 8529 | 4 | 8 | 28 | |
| GSE54993 | CYP4F2 | 8529 | 15 | 4 | 51 | |
| GSE54994 | CYP4F2 | 8529 | 6 | 14 | 33 | |
| GSE60625 | CYP4F2 | 8529 | 9 | 0 | 2 | |
| GSE74703 | CYP4F2 | 8529 | 2 | 4 | 30 | |
| GSE74704 | CYP4F2 | 8529 | 0 | 1 | 19 | |
| TCGA | CYP4F2 | 8529 | 18 | 12 | 66 |
Total number of gains: 110; Total number of losses: 53; Total Number of normals: 325.
Somatic mutations of CYP4F2:
Generating mutation plots.
Highly correlated genes for CYP4F2:
Showing top 20/399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP4F2 | CYP4F3 | 0.816292 | 12 | 0 | 12 |
| CYP4F2 | CYP4F11 | 0.713016 | 12 | 0 | 12 |
| CYP4F2 | FUT2 | 0.707451 | 4 | 0 | 3 |
| CYP4F2 | CYP4F8 | 0.700485 | 7 | 0 | 6 |
| CYP4F2 | RORC | 0.69317 | 3 | 0 | 3 |
| CYP4F2 | LDHD | 0.677954 | 4 | 0 | 3 |
| CYP4F2 | MUC15 | 0.674593 | 4 | 0 | 4 |
| CYP4F2 | PIGR | 0.671515 | 3 | 0 | 3 |
| CYP4F2 | TMEM45B | 0.668216 | 5 | 0 | 4 |
| CYP4F2 | ALDH3A1 | 0.667064 | 13 | 0 | 12 |
| CYP4F2 | C15orf62 | 0.665075 | 4 | 0 | 4 |
| CYP4F2 | MASP1 | 0.660129 | 3 | 0 | 3 |
| CYP4F2 | CNR1 | 0.659785 | 3 | 0 | 3 |
| CYP4F2 | ME1 | 0.658326 | 11 | 0 | 11 |
| CYP4F2 | PTGR1 | 0.657507 | 9 | 0 | 8 |
| CYP4F2 | ZNF770 | 0.655837 | 4 | 0 | 3 |
| CYP4F2 | AKR1B10 | 0.655545 | 11 | 0 | 10 |
| CYP4F2 | TALDO1 | 0.655336 | 10 | 0 | 8 |
| CYP4F2 | CXCR2 | 0.653819 | 4 | 0 | 3 |
| CYP4F2 | LRRC20 | 0.645042 | 4 | 0 | 3 |
For details and further investigation, click here
