| Full name: Rho related BTB domain containing 3 | Alias Symbol: KIAA0878 | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 22836 | HGNC ID: HGNC:18757 | Ensembl Gene: ENSG00000164292 | OMIM ID: 607353 |
| Drug and gene relationship at DGIdb | |||
Expression of RHOBTB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHOBTB3 | 22836 | 225202_at | -0.7523 | 0.4038 | |
| GSE20347 | RHOBTB3 | 22836 | 202975_s_at | 1.7840 | 0.0000 | |
| GSE23400 | RHOBTB3 | 22836 | 202975_s_at | 0.3022 | 0.0051 | |
| GSE26886 | RHOBTB3 | 22836 | 225202_at | 3.0401 | 0.0000 | |
| GSE29001 | RHOBTB3 | 22836 | 202975_s_at | 0.8907 | 0.0059 | |
| GSE38129 | RHOBTB3 | 22836 | 202976_s_at | 0.7239 | 0.0701 | |
| GSE45670 | RHOBTB3 | 22836 | 225202_at | -0.9445 | 0.0241 | |
| GSE53622 | RHOBTB3 | 22836 | 19758 | 0.4336 | 0.0016 | |
| GSE53624 | RHOBTB3 | 22836 | 19758 | 0.9256 | 0.0000 | |
| GSE63941 | RHOBTB3 | 22836 | 225202_at | -2.2467 | 0.0316 | |
| GSE77861 | RHOBTB3 | 22836 | 240111_at | 0.0353 | 0.8021 | |
| GSE97050 | RHOBTB3 | 22836 | A_33_P3288189 | -0.1921 | 0.6212 | |
| SRP007169 | RHOBTB3 | 22836 | RNAseq | 2.5440 | 0.0000 | |
| SRP008496 | RHOBTB3 | 22836 | RNAseq | 3.3283 | 0.0000 | |
| SRP064894 | RHOBTB3 | 22836 | RNAseq | 0.3377 | 0.3971 | |
| SRP133303 | RHOBTB3 | 22836 | RNAseq | 0.4111 | 0.1655 | |
| SRP159526 | RHOBTB3 | 22836 | RNAseq | -0.0315 | 0.9172 | |
| SRP193095 | RHOBTB3 | 22836 | RNAseq | 1.4637 | 0.0000 | |
| SRP219564 | RHOBTB3 | 22836 | RNAseq | 0.1382 | 0.7632 | |
| TCGA | RHOBTB3 | 22836 | RNAseq | -0.4300 | 0.0001 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by RHOBTB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHOBTB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHOBTB3 | 22836 | 1 | 13 | 16 | |
| GSE20123 | RHOBTB3 | 22836 | 1 | 13 | 16 | |
| GSE43470 | RHOBTB3 | 22836 | 3 | 9 | 31 | |
| GSE46452 | RHOBTB3 | 22836 | 0 | 28 | 31 | |
| GSE47630 | RHOBTB3 | 22836 | 0 | 20 | 20 | |
| GSE54993 | RHOBTB3 | 22836 | 8 | 1 | 61 | |
| GSE54994 | RHOBTB3 | 22836 | 1 | 18 | 34 | |
| GSE60625 | RHOBTB3 | 22836 | 0 | 0 | 11 | |
| GSE74703 | RHOBTB3 | 22836 | 2 | 7 | 27 | |
| GSE74704 | RHOBTB3 | 22836 | 1 | 7 | 12 | |
| TCGA | RHOBTB3 | 22836 | 3 | 44 | 49 |
Total number of gains: 20; Total number of losses: 160; Total Number of normals: 308.
Somatic mutations of RHOBTB3:
Generating mutation plots.
Highly correlated genes for RHOBTB3:
Showing top 20/979 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHOBTB3 | MAK16 | 0.762674 | 3 | 0 | 3 |
| RHOBTB3 | RHOT1 | 0.748339 | 3 | 0 | 3 |
| RHOBTB3 | DNAJC24 | 0.737279 | 3 | 0 | 3 |
| RHOBTB3 | SEC22A | 0.729032 | 4 | 0 | 4 |
| RHOBTB3 | LNPEP | 0.721364 | 3 | 0 | 3 |
| RHOBTB3 | LRRCC1 | 0.721088 | 4 | 0 | 4 |
| RHOBTB3 | UBR5 | 0.720454 | 3 | 0 | 3 |
| RHOBTB3 | CDC42EP4 | 0.715881 | 3 | 0 | 3 |
| RHOBTB3 | DZIP1L | 0.715002 | 3 | 0 | 3 |
| RHOBTB3 | TTC7B | 0.713596 | 4 | 0 | 4 |
| RHOBTB3 | LRRC23 | 0.71353 | 3 | 0 | 3 |
| RHOBTB3 | C11orf96 | 0.713304 | 5 | 0 | 4 |
| RHOBTB3 | MYADM | 0.711964 | 5 | 0 | 4 |
| RHOBTB3 | ST6GALNAC6 | 0.707989 | 3 | 0 | 3 |
| RHOBTB3 | GXYLT2 | 0.70768 | 5 | 0 | 5 |
| RHOBTB3 | FKBP7 | 0.702081 | 7 | 0 | 6 |
| RHOBTB3 | EIF5A2 | 0.696963 | 7 | 0 | 5 |
| RHOBTB3 | FIGN | 0.692312 | 4 | 0 | 3 |
| RHOBTB3 | NEK6 | 0.69118 | 5 | 0 | 5 |
| RHOBTB3 | SLC41A1 | 0.689748 | 4 | 0 | 4 |
For details and further investigation, click here
