| Full name: ras homolog family member T1 | Alias Symbol: MIRO-1|FLJ11040|MIRO1 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 55288 | HGNC ID: HGNC:21168 | Ensembl Gene: ENSG00000126858 | OMIM ID: 613888 |
| Drug and gene relationship at DGIdb | |||
Expression of RHOT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHOT1 | 55288 | 218323_at | -0.3808 | 0.1498 | |
| GSE20347 | RHOT1 | 55288 | 218323_at | -0.2857 | 0.1009 | |
| GSE23400 | RHOT1 | 55288 | 222148_s_at | -0.0088 | 0.9033 | |
| GSE26886 | RHOT1 | 55288 | 218323_at | -0.0750 | 0.6952 | |
| GSE29001 | RHOT1 | 55288 | 218323_at | -0.2391 | 0.1871 | |
| GSE38129 | RHOT1 | 55288 | 218323_at | -0.2256 | 0.0616 | |
| GSE45670 | RHOT1 | 55288 | 222148_s_at | -0.1733 | 0.2077 | |
| GSE53622 | RHOT1 | 55288 | 8869 | -0.2187 | 0.0001 | |
| GSE53624 | RHOT1 | 55288 | 18033 | -0.3750 | 0.0000 | |
| GSE63941 | RHOT1 | 55288 | 218323_at | -0.1687 | 0.5485 | |
| GSE77861 | RHOT1 | 55288 | 222148_s_at | 0.0668 | 0.8075 | |
| GSE97050 | RHOT1 | 55288 | A_33_P3326530 | -0.4743 | 0.1449 | |
| SRP007169 | RHOT1 | 55288 | RNAseq | -0.7113 | 0.0195 | |
| SRP008496 | RHOT1 | 55288 | RNAseq | -0.7296 | 0.0002 | |
| SRP064894 | RHOT1 | 55288 | RNAseq | -0.6634 | 0.0003 | |
| SRP133303 | RHOT1 | 55288 | RNAseq | -0.7131 | 0.0000 | |
| SRP159526 | RHOT1 | 55288 | RNAseq | -0.1746 | 0.3753 | |
| SRP193095 | RHOT1 | 55288 | RNAseq | -0.6412 | 0.0000 | |
| SRP219564 | RHOT1 | 55288 | RNAseq | -0.7867 | 0.0110 | |
| TCGA | RHOT1 | 55288 | RNAseq | -0.1210 | 0.0114 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RHOT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHOT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHOT1 | 55288 | 9 | 2 | 19 | |
| GSE20123 | RHOT1 | 55288 | 8 | 2 | 20 | |
| GSE43470 | RHOT1 | 55288 | 1 | 1 | 41 | |
| GSE46452 | RHOT1 | 55288 | 33 | 1 | 25 | |
| GSE47630 | RHOT1 | 55288 | 7 | 1 | 32 | |
| GSE54993 | RHOT1 | 55288 | 3 | 3 | 64 | |
| GSE54994 | RHOT1 | 55288 | 7 | 6 | 40 | |
| GSE60625 | RHOT1 | 55288 | 4 | 0 | 7 | |
| GSE74703 | RHOT1 | 55288 | 1 | 1 | 34 | |
| GSE74704 | RHOT1 | 55288 | 6 | 2 | 12 | |
| TCGA | RHOT1 | 55288 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 29; Total Number of normals: 360.
Somatic mutations of RHOT1:
Generating mutation plots.
Highly correlated genes for RHOT1:
Showing top 20/282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHOT1 | PTPRB | 0.774885 | 3 | 0 | 3 |
| RHOT1 | RHOBTB3 | 0.748339 | 3 | 0 | 3 |
| RHOT1 | FNIP2 | 0.744453 | 3 | 0 | 3 |
| RHOT1 | CHM | 0.742549 | 3 | 0 | 3 |
| RHOT1 | MIER1 | 0.724298 | 3 | 0 | 3 |
| RHOT1 | NR1H2 | 0.721588 | 3 | 0 | 3 |
| RHOT1 | C9orf85 | 0.713634 | 3 | 0 | 3 |
| RHOT1 | KIAA1191 | 0.704064 | 4 | 0 | 3 |
| RHOT1 | CYP2C19 | 0.702424 | 3 | 0 | 3 |
| RHOT1 | FBXL3 | 0.700387 | 4 | 0 | 3 |
| RHOT1 | PTGR1 | 0.69646 | 3 | 0 | 3 |
| RHOT1 | UHRF1BP1L | 0.693496 | 4 | 0 | 3 |
| RHOT1 | ZNF214 | 0.684276 | 3 | 0 | 3 |
| RHOT1 | ABCG2 | 0.67935 | 4 | 0 | 3 |
| RHOT1 | ARL4A | 0.676873 | 4 | 0 | 3 |
| RHOT1 | ZRANB1 | 0.671349 | 4 | 0 | 3 |
| RHOT1 | PTAR1 | 0.670747 | 4 | 0 | 3 |
| RHOT1 | SLC22A15 | 0.668038 | 3 | 0 | 3 |
| RHOT1 | DUSP22 | 0.667712 | 4 | 0 | 3 |
| RHOT1 | FNIP1 | 0.658869 | 4 | 0 | 3 |
For details and further investigation, click here
