| Full name: methyl-CpG binding domain protein 5 | Alias Symbol: FLJ11113|KIAA1461 | ||
| Type: protein-coding gene | Cytoband: 2q23.2 | ||
| Entrez ID: 55777 | HGNC ID: HGNC:20444 | Ensembl Gene: ENSG00000204406 | OMIM ID: 611472 |
| Drug and gene relationship at DGIdb | |||
Expression of MBD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBD5 | 55777 | 220195_at | 0.0876 | 0.9011 | |
| GSE20347 | MBD5 | 55777 | 220195_at | -0.2415 | 0.0744 | |
| GSE23400 | MBD5 | 55777 | 220195_at | -0.0752 | 0.0633 | |
| GSE26886 | MBD5 | 55777 | 220195_at | 0.1780 | 0.4366 | |
| GSE29001 | MBD5 | 55777 | 220195_at | -0.0972 | 0.7465 | |
| GSE38129 | MBD5 | 55777 | 220195_at | -0.1763 | 0.1595 | |
| GSE45670 | MBD5 | 55777 | 220195_at | -0.1128 | 0.7233 | |
| GSE53622 | MBD5 | 55777 | 27286 | -0.6793 | 0.0000 | |
| GSE53624 | MBD5 | 55777 | 27286 | -0.4528 | 0.0000 | |
| GSE63941 | MBD5 | 55777 | 220195_at | -0.5934 | 0.3729 | |
| GSE77861 | MBD5 | 55777 | 220195_at | -0.2076 | 0.0872 | |
| GSE97050 | MBD5 | A_19_P00808408 | -0.5084 | 0.1817 | ||
| SRP007169 | MBD5 | 55777 | RNAseq | -0.4539 | 0.2604 | |
| SRP008496 | MBD5 | 55777 | RNAseq | -0.3885 | 0.1616 | |
| SRP064894 | MBD5 | 55777 | RNAseq | -0.2414 | 0.2820 | |
| SRP133303 | MBD5 | 55777 | RNAseq | -0.3645 | 0.1238 | |
| SRP159526 | MBD5 | 55777 | RNAseq | -0.5585 | 0.0388 | |
| SRP193095 | MBD5 | 55777 | RNAseq | -0.1236 | 0.4298 | |
| SRP219564 | MBD5 | 55777 | RNAseq | -0.6334 | 0.2900 | |
| TCGA | MBD5 | 55777 | RNAseq | -0.3119 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MBD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBD5 | 55777 | 4 | 2 | 24 | |
| GSE20123 | MBD5 | 55777 | 4 | 2 | 24 | |
| GSE43470 | MBD5 | 55777 | 3 | 1 | 39 | |
| GSE46452 | MBD5 | 55777 | 1 | 4 | 54 | |
| GSE47630 | MBD5 | 55777 | 5 | 3 | 32 | |
| GSE54993 | MBD5 | 55777 | 0 | 6 | 64 | |
| GSE54994 | MBD5 | 55777 | 11 | 2 | 40 | |
| GSE60625 | MBD5 | 55777 | 0 | 3 | 8 | |
| GSE74703 | MBD5 | 55777 | 2 | 1 | 33 | |
| GSE74704 | MBD5 | 55777 | 3 | 1 | 16 | |
| TCGA | MBD5 | 55777 | 22 | 11 | 63 |
Total number of gains: 55; Total number of losses: 36; Total Number of normals: 397.
Somatic mutations of MBD5:
Generating mutation plots.
Highly correlated genes for MBD5:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBD5 | CYP2U1 | 0.813885 | 3 | 0 | 3 |
| MBD5 | TMEM170B | 0.785545 | 3 | 0 | 3 |
| MBD5 | TNFSF12 | 0.784575 | 3 | 0 | 3 |
| MBD5 | JAM2 | 0.782022 | 3 | 0 | 3 |
| MBD5 | JAM3 | 0.773793 | 3 | 0 | 3 |
| MBD5 | AOC3 | 0.773254 | 3 | 0 | 3 |
| MBD5 | MEOX2 | 0.768512 | 3 | 0 | 3 |
| MBD5 | CDC73 | 0.761213 | 3 | 0 | 3 |
| MBD5 | ZNF25 | 0.759473 | 3 | 0 | 3 |
| MBD5 | NKX6-1 | 0.757947 | 3 | 0 | 3 |
| MBD5 | PDS5B | 0.755878 | 3 | 0 | 3 |
| MBD5 | PDE1A | 0.754903 | 3 | 0 | 3 |
| MBD5 | TMEM47 | 0.752254 | 3 | 0 | 3 |
| MBD5 | CTSO | 0.750451 | 3 | 0 | 3 |
| MBD5 | RAB9B | 0.748489 | 3 | 0 | 3 |
| MBD5 | ANXA6 | 0.746905 | 3 | 0 | 3 |
| MBD5 | FPGT | 0.736595 | 3 | 0 | 3 |
| MBD5 | SOBP | 0.734779 | 3 | 0 | 3 |
| MBD5 | ADARB1 | 0.734212 | 3 | 0 | 3 |
| MBD5 | PTBP2 | 0.733734 | 4 | 0 | 4 |
For details and further investigation, click here
