RNF148

 

Full name: ring finger protein 148 Alias Symbol: MGC35222
Type: protein-coding gene Cytoband: 7q31.32
Entrez ID: 378925 HGNC ID: HGNC:22411 Ensembl Gene: ENSG00000235631 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of RNF148:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF148 378925 242925_at -0.1723 0.6051
GSE26886 RNF148 378925 242925_at -0.0712 0.4483
GSE45670 RNF148 378925 242925_at 0.1190 0.2450
GSE53622 RNF148 378925 27244 0.2295 0.1920
GSE53624 RNF148 378925 27244 0.3658 0.0043
GSE63941 RNF148 378925 242925_at -0.0484 0.7646
GSE77861 RNF148 378925 242925_at -0.1465 0.1005
GSE97050 RNF148 378925 A_24_P170234 -0.1537 0.6443
TCGA RNF148 378925 RNAseq -1.1092 0.0536

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RNF148 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RNF148:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF148 378925 7 2 21
GSE20123 RNF148 378925 8 2 20
GSE43470 RNF148 378925 2 4 37
GSE46452 RNF148 378925 8 1 50
GSE47630 RNF148 378925 7 4 29
GSE54993 RNF148 378925 3 5 62
GSE54994 RNF148 378925 10 6 37
GSE60625 RNF148 378925 0 0 11
GSE74703 RNF148 378925 2 4 30
GSE74704 RNF148 378925 5 2 13
TCGA RNF148 378925 27 21 48

Total number of gains: 79; Total number of losses: 51; Total Number of normals: 358.  


 

Somatic mutations of RNF148:

 

Generating mutation plots.

 

Highly correlated genes for RNF148:

 

Showing top 20/51 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF148CLYBL0.738785303
RNF148KCND30.723442303
RNF148ADAL0.720764303
RNF148ARRB10.719024303
RNF148PHYHIPL0.718957303
RNF148ITPRIP0.71139303
RNF148NKX6-10.708116303
RNF148SLC25A230.706881303
RNF148SRR0.704905303
RNF148SOX100.702246303
RNF148RNASEH2C0.683715303
RNF148SYN30.683558303
RNF148MYL30.665759303
RNF148CSRNP10.659779303
RNF148MAPK120.658026303
RNF148RND10.65471303
RNF148BTD0.651937303
RNF148HAS10.646629303
RNF148EIF4E30.639126303
RNF148FAM200B0.638554303

For details and further investigation, click here