| Full name: ring finger protein 216 | Alias Symbol: TRIAD3|UBCE7IP1|ZIN | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 54476 | HGNC ID: HGNC:21698 | Ensembl Gene: ENSG00000011275 | OMIM ID: 609948 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF216:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF216 | 54476 | 227065_at | -0.1742 | 0.6884 | |
| GSE20347 | RNF216 | 54476 | 218425_at | 0.3658 | 0.0012 | |
| GSE23400 | RNF216 | 54476 | 218425_at | 0.1920 | 0.0123 | |
| GSE26886 | RNF216 | 54476 | 227065_at | 1.0282 | 0.0002 | |
| GSE29001 | RNF216 | 54476 | 218426_s_at | 0.3647 | 0.0773 | |
| GSE38129 | RNF216 | 54476 | 218425_at | 0.0732 | 0.6832 | |
| GSE45670 | RNF216 | 54476 | 227065_at | -0.2833 | 0.0139 | |
| GSE53622 | RNF216 | 54476 | 19347 | 0.2412 | 0.0007 | |
| GSE53624 | RNF216 | 54476 | 19347 | 0.6059 | 0.0000 | |
| GSE63941 | RNF216 | 54476 | 218425_at | 0.0287 | 0.9458 | |
| GSE77861 | RNF216 | 54476 | 227065_at | 0.0940 | 0.4101 | |
| GSE97050 | RNF216 | 54476 | A_33_P3326105 | -0.0179 | 0.9465 | |
| SRP007169 | RNF216 | 54476 | RNAseq | 0.8028 | 0.0586 | |
| SRP008496 | RNF216 | 54476 | RNAseq | 1.1896 | 0.0003 | |
| SRP064894 | RNF216 | 54476 | RNAseq | 0.5170 | 0.0001 | |
| SRP133303 | RNF216 | 54476 | RNAseq | 0.2987 | 0.0629 | |
| SRP159526 | RNF216 | 54476 | RNAseq | 0.4107 | 0.0089 | |
| SRP193095 | RNF216 | 54476 | RNAseq | 0.5834 | 0.0000 | |
| TCGA | RNF216 | 54476 | RNAseq | 0.0410 | 0.3893 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RNF216 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF216:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF216 | 54476 | 14 | 1 | 15 | |
| GSE20123 | RNF216 | 54476 | 14 | 1 | 15 | |
| GSE43470 | RNF216 | 54476 | 6 | 1 | 36 | |
| GSE46452 | RNF216 | 54476 | 13 | 1 | 45 | |
| GSE47630 | RNF216 | 54476 | 9 | 1 | 30 | |
| GSE54993 | RNF216 | 54476 | 0 | 6 | 64 | |
| GSE54994 | RNF216 | 54476 | 22 | 1 | 30 | |
| GSE60625 | RNF216 | 54476 | 0 | 0 | 11 | |
| GSE74703 | RNF216 | 54476 | 6 | 0 | 30 | |
| GSE74704 | RNF216 | 54476 | 9 | 0 | 11 | |
| TCGA | RNF216 | 54476 | 55 | 5 | 36 |
Total number of gains: 148; Total number of losses: 17; Total Number of normals: 323.
Somatic mutations of RNF216:
Generating mutation plots.
Highly correlated genes for RNF216:
Showing top 20/209 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF216 | SNAP91 | 0.800009 | 3 | 0 | 3 |
| RNF216 | ZNF182 | 0.742026 | 3 | 0 | 3 |
| RNF216 | INSC | 0.722245 | 3 | 0 | 3 |
| RNF216 | NECAB3 | 0.716131 | 3 | 0 | 3 |
| RNF216 | ALKBH5 | 0.701618 | 3 | 0 | 3 |
| RNF216 | GH1 | 0.69733 | 3 | 0 | 3 |
| RNF216 | CHD5 | 0.696586 | 5 | 0 | 4 |
| RNF216 | EPM2A | 0.695198 | 4 | 0 | 4 |
| RNF216 | ZC3H10 | 0.688506 | 3 | 0 | 3 |
| RNF216 | ARHGAP21 | 0.686304 | 3 | 0 | 3 |
| RNF216 | SHISA4 | 0.685735 | 4 | 0 | 4 |
| RNF216 | ARHGAP22 | 0.680135 | 4 | 0 | 3 |
| RNF216 | C9orf24 | 0.675995 | 4 | 0 | 4 |
| RNF216 | LENG1 | 0.675382 | 4 | 0 | 3 |
| RNF216 | SNAI2 | 0.672534 | 4 | 0 | 4 |
| RNF216 | E2F1 | 0.670373 | 5 | 0 | 4 |
| RNF216 | FAM110B | 0.669025 | 4 | 0 | 3 |
| RNF216 | USP51 | 0.667732 | 3 | 0 | 3 |
| RNF216 | COL24A1 | 0.666998 | 4 | 0 | 3 |
| RNF216 | ANKDD1A | 0.662688 | 3 | 0 | 3 |
For details and further investigation, click here
