| Full name: 3-oxoacid CoA-transferase 1 | Alias Symbol: SCOT | ||
| Type: protein-coding gene | Cytoband: 5p13.1 | ||
| Entrez ID: 5019 | HGNC ID: HGNC:8527 | Ensembl Gene: ENSG00000083720 | OMIM ID: 601424 |
| Drug and gene relationship at DGIdb | |||
Expression of OXCT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OXCT1 | 5019 | 202780_at | -0.6476 | 0.1257 | |
| GSE20347 | OXCT1 | 5019 | 202780_at | -0.9045 | 0.0003 | |
| GSE23400 | OXCT1 | 5019 | 202780_at | -0.4986 | 0.0000 | |
| GSE26886 | OXCT1 | 5019 | 202780_at | -0.7314 | 0.0188 | |
| GSE29001 | OXCT1 | 5019 | 202780_at | -0.7372 | 0.0275 | |
| GSE38129 | OXCT1 | 5019 | 202780_at | -1.0152 | 0.0000 | |
| GSE45670 | OXCT1 | 5019 | 202780_at | -0.8053 | 0.0000 | |
| GSE53622 | OXCT1 | 5019 | 97964 | -0.8705 | 0.0000 | |
| GSE53624 | OXCT1 | 5019 | 97964 | -0.8970 | 0.0000 | |
| GSE63941 | OXCT1 | 5019 | 202780_at | -0.7904 | 0.4885 | |
| GSE77861 | OXCT1 | 5019 | 202780_at | -0.9630 | 0.0124 | |
| GSE97050 | OXCT1 | 5019 | A_32_P63848 | -1.1093 | 0.0959 | |
| SRP007169 | OXCT1 | 5019 | RNAseq | 0.3030 | 0.6005 | |
| SRP008496 | OXCT1 | 5019 | RNAseq | 0.1426 | 0.7384 | |
| SRP064894 | OXCT1 | 5019 | RNAseq | -0.7528 | 0.0004 | |
| SRP133303 | OXCT1 | 5019 | RNAseq | -0.6962 | 0.0096 | |
| SRP159526 | OXCT1 | 5019 | RNAseq | -1.0261 | 0.0117 | |
| SRP193095 | OXCT1 | 5019 | RNAseq | -1.2715 | 0.0000 | |
| SRP219564 | OXCT1 | 5019 | RNAseq | -0.7841 | 0.1187 | |
| TCGA | OXCT1 | 5019 | RNAseq | -0.3966 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by OXCT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OXCT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OXCT1 | 5019 | 9 | 0 | 21 | |
| GSE20123 | OXCT1 | 5019 | 9 | 0 | 21 | |
| GSE43470 | OXCT1 | 5019 | 17 | 0 | 26 | |
| GSE46452 | OXCT1 | 5019 | 5 | 22 | 32 | |
| GSE47630 | OXCT1 | 5019 | 6 | 12 | 22 | |
| GSE54993 | OXCT1 | 5019 | 6 | 3 | 61 | |
| GSE54994 | OXCT1 | 5019 | 24 | 2 | 27 | |
| GSE60625 | OXCT1 | 5019 | 0 | 0 | 11 | |
| GSE74703 | OXCT1 | 5019 | 13 | 0 | 23 | |
| GSE74704 | OXCT1 | 5019 | 8 | 0 | 12 | |
| TCGA | OXCT1 | 5019 | 51 | 6 | 39 |
Total number of gains: 148; Total number of losses: 45; Total Number of normals: 295.
Somatic mutations of OXCT1:
Generating mutation plots.
Highly correlated genes for OXCT1:
Showing top 20/1081 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OXCT1 | RNPC3 | 0.765676 | 3 | 0 | 3 |
| OXCT1 | GUF1 | 0.756184 | 4 | 0 | 4 |
| OXCT1 | MRVI1 | 0.731721 | 4 | 0 | 3 |
| OXCT1 | FAM219B | 0.716023 | 4 | 0 | 4 |
| OXCT1 | ALDH1A2 | 0.714305 | 3 | 0 | 3 |
| OXCT1 | GNPDA2 | 0.713921 | 5 | 0 | 4 |
| OXCT1 | ANGPTL1 | 0.709269 | 5 | 0 | 4 |
| OXCT1 | USP48 | 0.703324 | 4 | 0 | 4 |
| OXCT1 | DOCK8 | 0.70096 | 4 | 0 | 3 |
| OXCT1 | RBPMS | 0.699719 | 10 | 0 | 9 |
| OXCT1 | SPAG8 | 0.698761 | 4 | 0 | 3 |
| OXCT1 | FBXO10 | 0.696955 | 3 | 0 | 3 |
| OXCT1 | XKR4 | 0.696197 | 5 | 0 | 5 |
| OXCT1 | NR2C2 | 0.695131 | 3 | 0 | 3 |
| OXCT1 | SLMAP | 0.686947 | 7 | 0 | 7 |
| OXCT1 | NLRP12 | 0.684453 | 3 | 0 | 3 |
| OXCT1 | YPEL2 | 0.681479 | 4 | 0 | 3 |
| OXCT1 | C2CD2 | 0.678468 | 3 | 0 | 3 |
| OXCT1 | GYPC | 0.678002 | 8 | 0 | 8 |
| OXCT1 | GNL3 | 0.676975 | 3 | 0 | 3 |
For details and further investigation, click here
