| Full name: NADH:ubiquinone oxidoreductase subunit S4 | Alias Symbol: AQDQ|CI-18 | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 4724 | HGNC ID: HGNC:7711 | Ensembl Gene: ENSG00000164258 | OMIM ID: 602694 |
| Drug and gene relationship at DGIdb | |||
Expression of NDUFS4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFS4 | 4724 | 209303_at | -0.9200 | 0.0937 | |
| GSE20347 | NDUFS4 | 4724 | 209303_at | -0.6433 | 0.0014 | |
| GSE23400 | NDUFS4 | 4724 | 209303_at | -0.3668 | 0.0000 | |
| GSE26886 | NDUFS4 | 4724 | 209303_at | 0.3926 | 0.1058 | |
| GSE29001 | NDUFS4 | 4724 | 209303_at | -0.6039 | 0.0366 | |
| GSE38129 | NDUFS4 | 4724 | 209303_at | -0.4936 | 0.0011 | |
| GSE45670 | NDUFS4 | 4724 | 209303_at | -0.3969 | 0.0011 | |
| GSE53622 | NDUFS4 | 4724 | 3147 | -0.4644 | 0.0000 | |
| GSE53624 | NDUFS4 | 4724 | 3147 | -0.4301 | 0.0000 | |
| GSE63941 | NDUFS4 | 4724 | 209303_at | 0.0619 | 0.8827 | |
| GSE77861 | NDUFS4 | 4724 | 209303_at | -0.7795 | 0.0274 | |
| GSE97050 | NDUFS4 | 4724 | A_23_P257198 | -0.4351 | 0.1703 | |
| SRP007169 | NDUFS4 | 4724 | RNAseq | -1.0229 | 0.0107 | |
| SRP008496 | NDUFS4 | 4724 | RNAseq | -1.3343 | 0.0000 | |
| SRP064894 | NDUFS4 | 4724 | RNAseq | -0.6535 | 0.0078 | |
| SRP133303 | NDUFS4 | 4724 | RNAseq | -0.2812 | 0.0287 | |
| SRP159526 | NDUFS4 | 4724 | RNAseq | -0.4191 | 0.3842 | |
| SRP193095 | NDUFS4 | 4724 | RNAseq | -1.0707 | 0.0000 | |
| SRP219564 | NDUFS4 | 4724 | RNAseq | -0.7781 | 0.0030 | |
| TCGA | NDUFS4 | 4724 | RNAseq | -0.1683 | 0.0054 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by NDUFS4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFS4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFS4 | 4724 | 1 | 13 | 16 | |
| GSE20123 | NDUFS4 | 4724 | 1 | 13 | 16 | |
| GSE43470 | NDUFS4 | 4724 | 1 | 12 | 30 | |
| GSE46452 | NDUFS4 | 4724 | 1 | 27 | 31 | |
| GSE47630 | NDUFS4 | 4724 | 2 | 16 | 22 | |
| GSE54993 | NDUFS4 | 4724 | 8 | 1 | 61 | |
| GSE54994 | NDUFS4 | 4724 | 5 | 17 | 31 | |
| GSE60625 | NDUFS4 | 4724 | 0 | 0 | 11 | |
| GSE74703 | NDUFS4 | 4724 | 1 | 9 | 26 | |
| GSE74704 | NDUFS4 | 4724 | 1 | 6 | 13 | |
| TCGA | NDUFS4 | 4724 | 10 | 45 | 41 |
Total number of gains: 31; Total number of losses: 159; Total Number of normals: 298.
Somatic mutations of NDUFS4:
Generating mutation plots.
Highly correlated genes for NDUFS4:
Showing top 20/890 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFS4 | ZNF585A | 0.796262 | 3 | 0 | 3 |
| NDUFS4 | SLC43A3 | 0.795609 | 3 | 0 | 3 |
| NDUFS4 | THRB | 0.771996 | 3 | 0 | 3 |
| NDUFS4 | HDHD2 | 0.76134 | 3 | 0 | 3 |
| NDUFS4 | RNF185 | 0.756136 | 3 | 0 | 3 |
| NDUFS4 | METTL5 | 0.752527 | 3 | 0 | 3 |
| NDUFS4 | MBNL3 | 0.747498 | 4 | 0 | 4 |
| NDUFS4 | TMEM126A | 0.744758 | 3 | 0 | 3 |
| NDUFS4 | MALT1 | 0.723006 | 5 | 0 | 5 |
| NDUFS4 | CETN3 | 0.709632 | 8 | 0 | 8 |
| NDUFS4 | CCDC90B | 0.708279 | 6 | 0 | 6 |
| NDUFS4 | MFN1 | 0.705491 | 3 | 0 | 3 |
| NDUFS4 | MITD1 | 0.704974 | 3 | 0 | 3 |
| NDUFS4 | DCAF10 | 0.704384 | 5 | 0 | 4 |
| NDUFS4 | CYP2C19 | 0.699006 | 3 | 0 | 3 |
| NDUFS4 | DHX29 | 0.695144 | 12 | 0 | 11 |
| NDUFS4 | UBE4A | 0.692585 | 3 | 0 | 3 |
| NDUFS4 | MOCS2 | 0.689861 | 11 | 0 | 9 |
| NDUFS4 | PAPSS2 | 0.689561 | 3 | 0 | 3 |
| NDUFS4 | HIPK3 | 0.688942 | 5 | 0 | 4 |
For details and further investigation, click here
