| Full name: transmembrane protein 115 | Alias Symbol: PL6 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 11070 | HGNC ID: HGNC:30055 | Ensembl Gene: ENSG00000126062 | OMIM ID: 607069 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM115:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM115 | 11070 | 216267_s_at | 0.2140 | 0.4243 | |
| GSE20347 | TMEM115 | 11070 | 216267_s_at | -0.3816 | 0.0006 | |
| GSE23400 | TMEM115 | 11070 | 216267_s_at | -0.0849 | 0.0405 | |
| GSE26886 | TMEM115 | 11070 | 216267_s_at | -0.2878 | 0.1712 | |
| GSE29001 | TMEM115 | 11070 | 216267_s_at | -0.3523 | 0.0126 | |
| GSE38129 | TMEM115 | 11070 | 216267_s_at | -0.2559 | 0.0033 | |
| GSE45670 | TMEM115 | 11070 | 216267_s_at | -0.0562 | 0.5476 | |
| GSE53622 | TMEM115 | 11070 | 83358 | -0.1720 | 0.0034 | |
| GSE53624 | TMEM115 | 11070 | 83358 | -0.1526 | 0.0037 | |
| GSE63941 | TMEM115 | 11070 | 216267_s_at | 0.1646 | 0.6289 | |
| GSE77861 | TMEM115 | 11070 | 216267_s_at | -0.1104 | 0.6669 | |
| GSE97050 | TMEM115 | 11070 | A_23_P6869 | -0.1713 | 0.3759 | |
| SRP007169 | TMEM115 | 11070 | RNAseq | -0.2984 | 0.4824 | |
| SRP008496 | TMEM115 | 11070 | RNAseq | -0.0934 | 0.7520 | |
| SRP064894 | TMEM115 | 11070 | RNAseq | 0.0153 | 0.9571 | |
| SRP133303 | TMEM115 | 11070 | RNAseq | -0.2947 | 0.0309 | |
| SRP159526 | TMEM115 | 11070 | RNAseq | -0.1365 | 0.5026 | |
| SRP193095 | TMEM115 | 11070 | RNAseq | -0.2779 | 0.0112 | |
| SRP219564 | TMEM115 | 11070 | RNAseq | -0.2066 | 0.5595 | |
| TCGA | TMEM115 | 11070 | RNAseq | -0.1354 | 0.0077 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM115 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM115:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM115 | 11070 | 0 | 18 | 12 | |
| GSE20123 | TMEM115 | 11070 | 0 | 19 | 11 | |
| GSE43470 | TMEM115 | 11070 | 0 | 19 | 24 | |
| GSE46452 | TMEM115 | 11070 | 2 | 16 | 41 | |
| GSE47630 | TMEM115 | 11070 | 1 | 24 | 15 | |
| GSE54993 | TMEM115 | 11070 | 6 | 2 | 62 | |
| GSE54994 | TMEM115 | 11070 | 0 | 34 | 19 | |
| GSE60625 | TMEM115 | 11070 | 5 | 0 | 6 | |
| GSE74703 | TMEM115 | 11070 | 0 | 15 | 21 | |
| GSE74704 | TMEM115 | 11070 | 0 | 12 | 8 | |
| TCGA | TMEM115 | 11070 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of TMEM115:
Generating mutation plots.
Highly correlated genes for TMEM115:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM115 | PRCC | 0.785424 | 3 | 0 | 3 |
| TMEM115 | ZNF502 | 0.773089 | 3 | 0 | 3 |
| TMEM115 | TYW1 | 0.771304 | 3 | 0 | 3 |
| TMEM115 | HIC2 | 0.758277 | 3 | 0 | 3 |
| TMEM115 | ZNF408 | 0.75731 | 3 | 0 | 3 |
| TMEM115 | C2orf76 | 0.745383 | 3 | 0 | 3 |
| TMEM115 | KCTD15 | 0.744372 | 4 | 0 | 4 |
| TMEM115 | ADCK1 | 0.744292 | 4 | 0 | 4 |
| TMEM115 | RPRD2 | 0.732634 | 3 | 0 | 3 |
| TMEM115 | SCAMP3 | 0.731864 | 3 | 0 | 3 |
| TMEM115 | ZNF747 | 0.726279 | 3 | 0 | 3 |
| TMEM115 | SLC35B3 | 0.726139 | 3 | 0 | 3 |
| TMEM115 | ABHD16A | 0.719818 | 4 | 0 | 4 |
| TMEM115 | PROSER1 | 0.713711 | 4 | 0 | 3 |
| TMEM115 | B3GALNT2 | 0.711499 | 3 | 0 | 3 |
| TMEM115 | INO80E | 0.700585 | 3 | 0 | 3 |
| TMEM115 | YIPF3 | 0.698918 | 4 | 0 | 4 |
| TMEM115 | MBOAT1 | 0.696586 | 3 | 0 | 3 |
| TMEM115 | ALG3 | 0.69628 | 3 | 0 | 3 |
| TMEM115 | UROS | 0.6922 | 5 | 0 | 4 |
For details and further investigation, click here
