| Full name: R-spondin 4 | Alias Symbol: dJ824F16.3 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 343637 | HGNC ID: HGNC:16175 | Ensembl Gene: ENSG00000101282 | OMIM ID: 610573 |
Expression of RSPO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RSPO4 | 343637 | 237423_at | 0.5024 | 0.3002 | |
| GSE26886 | RSPO4 | 343637 | 237423_at | 0.3652 | 0.0655 | |
| GSE45670 | RSPO4 | 343637 | 237423_at | -0.0199 | 0.9039 | |
| GSE53622 | RSPO4 | 343637 | 37789 | 0.0755 | 0.8397 | |
| GSE53624 | RSPO4 | 343637 | 37789 | -0.1451 | 0.5578 | |
| GSE63941 | RSPO4 | 343637 | 237423_at | 0.5775 | 0.1365 | |
| GSE77861 | RSPO4 | 343637 | 237423_at | -0.0930 | 0.3350 | |
| SRP159526 | RSPO4 | 343637 | RNAseq | 0.9119 | 0.1681 | |
| SRP219564 | RSPO4 | 343637 | RNAseq | 2.6553 | 0.0009 | |
| TCGA | RSPO4 | 343637 | RNAseq | 0.5894 | 0.3386 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RSPO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RSPO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RSPO4 | 343637 | 12 | 4 | 14 | |
| GSE20123 | RSPO4 | 343637 | 13 | 4 | 13 | |
| GSE43470 | RSPO4 | 343637 | 12 | 1 | 30 | |
| GSE46452 | RSPO4 | 343637 | 26 | 1 | 32 | |
| GSE47630 | RSPO4 | 343637 | 19 | 4 | 17 | |
| GSE54993 | RSPO4 | 343637 | 2 | 14 | 54 | |
| GSE54994 | RSPO4 | 343637 | 24 | 2 | 27 | |
| GSE60625 | RSPO4 | 343637 | 0 | 0 | 11 | |
| GSE74703 | RSPO4 | 343637 | 11 | 1 | 24 | |
| GSE74704 | RSPO4 | 343637 | 8 | 2 | 10 | |
| TCGA | RSPO4 | 343637 | 41 | 11 | 44 |
Total number of gains: 168; Total number of losses: 44; Total Number of normals: 276.
Somatic mutations of RSPO4:
Generating mutation plots.
Highly correlated genes for RSPO4:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RSPO4 | BARX1 | 0.643371 | 3 | 0 | 3 |
| RSPO4 | SLC5A12 | 0.636944 | 3 | 0 | 3 |
| RSPO4 | TRIM47 | 0.631729 | 3 | 0 | 3 |
| RSPO4 | MMP25 | 0.625785 | 3 | 0 | 3 |
| RSPO4 | SLC17A9 | 0.615771 | 3 | 0 | 3 |
| RSPO4 | NPEPL1 | 0.615565 | 3 | 0 | 3 |
| RSPO4 | MCEMP1 | 0.608819 | 3 | 0 | 3 |
| RSPO4 | COL23A1 | 0.604543 | 4 | 0 | 3 |
| RSPO4 | TNFRSF9 | 0.600878 | 3 | 0 | 3 |
| RSPO4 | IL32 | 0.592417 | 3 | 0 | 3 |
| RSPO4 | SUSD3 | 0.587484 | 4 | 0 | 3 |
| RSPO4 | TMEM51-AS1 | 0.58568 | 3 | 0 | 3 |
| RSPO4 | HCG26 | 0.581458 | 3 | 0 | 3 |
| RSPO4 | PSORS1C3 | 0.579192 | 3 | 0 | 3 |
| RSPO4 | TMEM121 | 0.572719 | 6 | 0 | 5 |
| RSPO4 | ARHGAP4 | 0.569312 | 3 | 0 | 3 |
| RSPO4 | HAGLR | 0.566507 | 3 | 0 | 3 |
| RSPO4 | CCL7 | 0.563751 | 3 | 0 | 3 |
| RSPO4 | CCDC151 | 0.562785 | 4 | 0 | 3 |
| RSPO4 | FOXS1 | 0.559948 | 3 | 0 | 3 |
For details and further investigation, click here
