| Full name: solute carrier family 5 member 12 | Alias Symbol: MGC52019|SMCT2 | ||
| Type: protein-coding gene | Cytoband: 11p14.2 | ||
| Entrez ID: 159963 | HGNC ID: HGNC:28750 | Ensembl Gene: ENSG00000148942 | OMIM ID: 612455 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A12 | 159963 | 1561951_at | 0.3536 | 0.1171 | |
| GSE20347 | SLC5A12 | 159963 | 214389_at | 0.0156 | 0.7674 | |
| GSE23400 | SLC5A12 | 159963 | 214389_at | 0.0069 | 0.6823 | |
| GSE26886 | SLC5A12 | 159963 | 1561951_at | 0.4355 | 0.0170 | |
| GSE29001 | SLC5A12 | 159963 | 214389_at | 0.2056 | 0.0991 | |
| GSE38129 | SLC5A12 | 159963 | 214389_at | -0.0030 | 0.9540 | |
| GSE45670 | SLC5A12 | 159963 | 1561951_at | 0.4082 | 0.1178 | |
| GSE53622 | SLC5A12 | 159963 | 22831 | 3.6580 | 0.0000 | |
| GSE53624 | SLC5A12 | 159963 | 22831 | 2.7912 | 0.0000 | |
| GSE63941 | SLC5A12 | 159963 | 1561951_at | 0.5089 | 0.0966 | |
| GSE77861 | SLC5A12 | 159963 | 1561951_at | -0.0809 | 0.5475 | |
| GSE97050 | SLC5A12 | 159963 | A_23_P323943 | 0.7816 | 0.2395 | |
| SRP159526 | SLC5A12 | 159963 | RNAseq | 3.6099 | 0.0000 | |
| SRP219564 | SLC5A12 | 159963 | RNAseq | 3.6945 | 0.0000 | |
| TCGA | SLC5A12 | 159963 | RNAseq | 3.7579 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SLC5A12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A12 | 159963 | 1 | 9 | 20 | |
| GSE20123 | SLC5A12 | 159963 | 1 | 8 | 21 | |
| GSE43470 | SLC5A12 | 159963 | 1 | 5 | 37 | |
| GSE46452 | SLC5A12 | 159963 | 7 | 5 | 47 | |
| GSE47630 | SLC5A12 | 159963 | 3 | 10 | 27 | |
| GSE54993 | SLC5A12 | 159963 | 3 | 0 | 67 | |
| GSE54994 | SLC5A12 | 159963 | 4 | 11 | 38 | |
| GSE60625 | SLC5A12 | 159963 | 0 | 0 | 11 | |
| GSE74703 | SLC5A12 | 159963 | 1 | 3 | 32 | |
| GSE74704 | SLC5A12 | 159963 | 0 | 8 | 12 | |
| TCGA | SLC5A12 | 159963 | 12 | 25 | 59 |
Total number of gains: 33; Total number of losses: 84; Total Number of normals: 371.
Somatic mutations of SLC5A12:
Generating mutation plots.
Highly correlated genes for SLC5A12:
Showing top 20/476 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A12 | C1QTNF6 | 0.797331 | 3 | 0 | 3 |
| SLC5A12 | STRA6 | 0.780581 | 3 | 0 | 3 |
| SLC5A12 | COLGALT1 | 0.780539 | 3 | 0 | 3 |
| SLC5A12 | SNAP47 | 0.745928 | 3 | 0 | 3 |
| SLC5A12 | CHPF2 | 0.71202 | 3 | 0 | 3 |
| SLC5A12 | NOP56 | 0.710419 | 3 | 0 | 3 |
| SLC5A12 | PSMC2 | 0.705419 | 4 | 0 | 4 |
| SLC5A12 | ATAD3C | 0.69036 | 3 | 0 | 3 |
| SLC5A12 | MMP11 | 0.687128 | 6 | 0 | 4 |
| SLC5A12 | EMC1 | 0.686136 | 4 | 0 | 4 |
| SLC5A12 | BIRC5 | 0.685883 | 4 | 0 | 4 |
| SLC5A12 | NAT14 | 0.681853 | 4 | 0 | 4 |
| SLC5A12 | TMC6 | 0.677321 | 4 | 0 | 4 |
| SLC5A12 | LBX2-AS1 | 0.676295 | 4 | 0 | 3 |
| SLC5A12 | CST2 | 0.671307 | 6 | 0 | 6 |
| SLC5A12 | SLC19A1 | 0.670739 | 3 | 0 | 3 |
| SLC5A12 | CKLF | 0.66739 | 3 | 0 | 3 |
| SLC5A12 | NTMT1 | 0.661826 | 3 | 0 | 3 |
| SLC5A12 | POSTN | 0.661506 | 6 | 0 | 4 |
| SLC5A12 | RNF2 | 0.660167 | 4 | 0 | 4 |
For details and further investigation, click here
