| Full name: ubiquitin specific peptidase 12 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 219333 | HGNC ID: HGNC:20485 | Ensembl Gene: ENSG00000152484 | OMIM ID: 603091 |
| Drug and gene relationship at DGIdb | |||
Expression of USP12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP12 | 219333 | 213327_s_at | -0.3059 | 0.6291 | |
| GSE20347 | USP12 | 219333 | 213327_s_at | 0.1437 | 0.3248 | |
| GSE23400 | USP12 | 219333 | 213327_s_at | 0.0166 | 0.8607 | |
| GSE26886 | USP12 | 219333 | 213327_s_at | -0.0612 | 0.8731 | |
| GSE29001 | USP12 | 219333 | 213327_s_at | 0.4348 | 0.1778 | |
| GSE38129 | USP12 | 219333 | 213327_s_at | -0.1197 | 0.6265 | |
| GSE45670 | USP12 | 219333 | 213327_s_at | -0.3390 | 0.1218 | |
| GSE53622 | USP12 | 219333 | 21220 | -0.3273 | 0.0021 | |
| GSE53624 | USP12 | 219333 | 21220 | -0.0241 | 0.7737 | |
| GSE63941 | USP12 | 219333 | 213327_s_at | -1.2559 | 0.0060 | |
| GSE77861 | USP12 | 219333 | 213327_s_at | 0.3095 | 0.1151 | |
| GSE97050 | USP12 | 219333 | A_24_P237613 | -0.3751 | 0.2092 | |
| SRP007169 | USP12 | 219333 | RNAseq | -0.0549 | 0.8851 | |
| SRP008496 | USP12 | 219333 | RNAseq | 0.2225 | 0.3656 | |
| SRP064894 | USP12 | 219333 | RNAseq | -0.0378 | 0.8615 | |
| SRP133303 | USP12 | 219333 | RNAseq | 0.4250 | 0.0310 | |
| SRP159526 | USP12 | 219333 | RNAseq | -0.1571 | 0.6538 | |
| SRP193095 | USP12 | 219333 | RNAseq | 0.0271 | 0.8347 | |
| SRP219564 | USP12 | 219333 | RNAseq | -0.3816 | 0.4452 | |
| TCGA | USP12 | 219333 | RNAseq | -0.3143 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by USP12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP12 | 219333 | 1 | 13 | 16 | |
| GSE20123 | USP12 | 219333 | 1 | 12 | 17 | |
| GSE43470 | USP12 | 219333 | 2 | 12 | 29 | |
| GSE46452 | USP12 | 219333 | 0 | 33 | 26 | |
| GSE47630 | USP12 | 219333 | 3 | 26 | 11 | |
| GSE54993 | USP12 | 219333 | 11 | 2 | 57 | |
| GSE54994 | USP12 | 219333 | 1 | 13 | 39 | |
| GSE60625 | USP12 | 219333 | 0 | 3 | 8 | |
| GSE74703 | USP12 | 219333 | 2 | 9 | 25 | |
| GSE74704 | USP12 | 219333 | 0 | 10 | 10 | |
| TCGA | USP12 | 219333 | 6 | 42 | 48 |
Total number of gains: 27; Total number of losses: 175; Total Number of normals: 286.
Somatic mutations of USP12:
Generating mutation plots.
Highly correlated genes for USP12:
Showing top 20/955 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP12 | SLC35D2 | 0.811994 | 3 | 0 | 3 |
| USP12 | GLI2 | 0.77726 | 3 | 0 | 3 |
| USP12 | USP22 | 0.765802 | 3 | 0 | 3 |
| USP12 | FEM1C | 0.760926 | 3 | 0 | 3 |
| USP12 | RTF1 | 0.759822 | 3 | 0 | 3 |
| USP12 | CD44 | 0.745692 | 3 | 0 | 3 |
| USP12 | KDSR | 0.742229 | 5 | 0 | 5 |
| USP12 | CADM2 | 0.740932 | 3 | 0 | 3 |
| USP12 | KBTBD6 | 0.739921 | 4 | 0 | 4 |
| USP12 | RP9 | 0.738069 | 3 | 0 | 3 |
| USP12 | SLC25A30 | 0.733219 | 4 | 0 | 4 |
| USP12 | WDR70 | 0.732304 | 3 | 0 | 3 |
| USP12 | TGFBR1 | 0.721404 | 3 | 0 | 3 |
| USP12 | CDC16 | 0.715096 | 3 | 0 | 3 |
| USP12 | ASB2 | 0.714935 | 3 | 0 | 3 |
| USP12 | CNST | 0.714802 | 3 | 0 | 3 |
| USP12 | RGMB | 0.713697 | 5 | 0 | 4 |
| USP12 | ANO6 | 0.713256 | 5 | 0 | 5 |
| USP12 | DCHS1 | 0.713209 | 6 | 0 | 5 |
| USP12 | ANTXR2 | 0.713102 | 5 | 0 | 5 |
For details and further investigation, click here
