| Full name: transmembrane protein 98 | Alias Symbol: DKFZP564K1964 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 26022 | HGNC ID: HGNC:24529 | Ensembl Gene: ENSG00000006042 | OMIM ID: 615949 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM98:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM98 | 26022 | 223170_at | -0.5108 | 0.6002 | |
| GSE26886 | TMEM98 | 26022 | 223170_at | 0.4476 | 0.2731 | |
| GSE45670 | TMEM98 | 26022 | 223170_at | -0.5016 | 0.2096 | |
| GSE53622 | TMEM98 | 26022 | 41678 | 0.2792 | 0.0724 | |
| GSE53624 | TMEM98 | 26022 | 41678 | 0.1318 | 0.3478 | |
| GSE63941 | TMEM98 | 26022 | 223170_at | -3.8626 | 0.0012 | |
| GSE77861 | TMEM98 | 26022 | 223170_at | 0.5406 | 0.1055 | |
| GSE97050 | TMEM98 | 26022 | A_23_P27035 | -0.1986 | 0.4799 | |
| SRP007169 | TMEM98 | 26022 | RNAseq | 0.3317 | 0.5289 | |
| SRP008496 | TMEM98 | 26022 | RNAseq | 1.2589 | 0.0016 | |
| SRP064894 | TMEM98 | 26022 | RNAseq | 0.1048 | 0.7457 | |
| SRP133303 | TMEM98 | 26022 | RNAseq | -0.0903 | 0.7628 | |
| SRP159526 | TMEM98 | 26022 | RNAseq | 1.0994 | 0.0083 | |
| SRP193095 | TMEM98 | 26022 | RNAseq | -0.4130 | 0.2084 | |
| SRP219564 | TMEM98 | 26022 | RNAseq | 0.0978 | 0.8631 | |
| TCGA | TMEM98 | 26022 | RNAseq | -0.4301 | 0.0005 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by TMEM98 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM98:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM98 | 26022 | 7 | 1 | 22 | |
| GSE20123 | TMEM98 | 26022 | 7 | 1 | 22 | |
| GSE43470 | TMEM98 | 26022 | 0 | 1 | 42 | |
| GSE46452 | TMEM98 | 26022 | 34 | 0 | 25 | |
| GSE47630 | TMEM98 | 26022 | 7 | 1 | 32 | |
| GSE54993 | TMEM98 | 26022 | 3 | 3 | 64 | |
| GSE54994 | TMEM98 | 26022 | 7 | 6 | 40 | |
| GSE60625 | TMEM98 | 26022 | 4 | 0 | 7 | |
| GSE74703 | TMEM98 | 26022 | 0 | 1 | 35 | |
| GSE74704 | TMEM98 | 26022 | 4 | 1 | 15 | |
| TCGA | TMEM98 | 26022 | 22 | 7 | 67 |
Total number of gains: 95; Total number of losses: 22; Total Number of normals: 371.
Somatic mutations of TMEM98:
Generating mutation plots.
Highly correlated genes for TMEM98:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM98 | CHL1 | 0.76321 | 3 | 0 | 3 |
| TMEM98 | USP45 | 0.757206 | 3 | 0 | 3 |
| TMEM98 | ZDHHC4 | 0.74783 | 3 | 0 | 3 |
| TMEM98 | RTF1 | 0.745248 | 3 | 0 | 3 |
| TMEM98 | PLSCR4 | 0.739639 | 3 | 0 | 3 |
| TMEM98 | TMOD2 | 0.739528 | 3 | 0 | 3 |
| TMEM98 | SOX5 | 0.731684 | 6 | 0 | 5 |
| TMEM98 | IL3RA | 0.72932 | 3 | 0 | 3 |
| TMEM98 | ADCY9 | 0.714946 | 3 | 0 | 3 |
| TMEM98 | ARHGEF33 | 0.712012 | 3 | 0 | 3 |
| TMEM98 | GRB14 | 0.71052 | 3 | 0 | 3 |
| TMEM98 | HERC2 | 0.702331 | 4 | 0 | 3 |
| TMEM98 | ST3GAL5 | 0.696961 | 3 | 0 | 3 |
| TMEM98 | DHRSX | 0.694998 | 4 | 0 | 4 |
| TMEM98 | LAPTM4A | 0.690977 | 3 | 0 | 3 |
| TMEM98 | MCAM | 0.684557 | 4 | 0 | 3 |
| TMEM98 | CSF1 | 0.68303 | 4 | 0 | 4 |
| TMEM98 | PRKAR2B | 0.680038 | 4 | 0 | 3 |
| TMEM98 | BDNF | 0.679858 | 4 | 0 | 3 |
| TMEM98 | LRRK1 | 0.677657 | 3 | 0 | 3 |
For details and further investigation, click here
