| Full name: transcriptional regulating factor 1 | Alias Symbol: TReP-132|HSA277276|RAPA|dJ139D8.5 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 55809 | HGNC ID: HGNC:18273 | Ensembl Gene: ENSG00000124496 | OMIM ID: 610322 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRERF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRERF1 | 55809 | 238520_at | -0.6976 | 0.4010 | |
| GSE26886 | TRERF1 | 55809 | 238520_at | -0.9995 | 0.0000 | |
| GSE45670 | TRERF1 | 55809 | 238520_at | -0.5756 | 0.0211 | |
| GSE53622 | TRERF1 | 55809 | 86227 | -0.7380 | 0.0000 | |
| GSE53624 | TRERF1 | 55809 | 3299 | -0.1977 | 0.0159 | |
| GSE63941 | TRERF1 | 55809 | 238520_at | -0.6340 | 0.5240 | |
| GSE77861 | TRERF1 | 55809 | 238520_at | -0.6043 | 0.0396 | |
| GSE97050 | TRERF1 | 55809 | A_23_P59022 | -0.3786 | 0.3445 | |
| SRP007169 | TRERF1 | 55809 | RNAseq | -0.5771 | 0.2291 | |
| SRP008496 | TRERF1 | 55809 | RNAseq | -0.9474 | 0.0136 | |
| SRP064894 | TRERF1 | 55809 | RNAseq | -0.6761 | 0.0070 | |
| SRP133303 | TRERF1 | 55809 | RNAseq | -0.7693 | 0.0079 | |
| SRP159526 | TRERF1 | 55809 | RNAseq | -1.3846 | 0.0002 | |
| SRP193095 | TRERF1 | 55809 | RNAseq | -0.5690 | 0.0000 | |
| SRP219564 | TRERF1 | 55809 | RNAseq | -0.3789 | 0.3493 | |
| TCGA | TRERF1 | 55809 | RNAseq | 0.1636 | 0.0682 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRERF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRERF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRERF1 | 55809 | 7 | 0 | 23 | |
| GSE20123 | TRERF1 | 55809 | 7 | 0 | 23 | |
| GSE43470 | TRERF1 | 55809 | 6 | 0 | 37 | |
| GSE46452 | TRERF1 | 55809 | 2 | 9 | 48 | |
| GSE47630 | TRERF1 | 55809 | 8 | 4 | 28 | |
| GSE54993 | TRERF1 | 55809 | 3 | 2 | 65 | |
| GSE54994 | TRERF1 | 55809 | 11 | 4 | 38 | |
| GSE60625 | TRERF1 | 55809 | 0 | 1 | 10 | |
| GSE74703 | TRERF1 | 55809 | 6 | 0 | 30 | |
| GSE74704 | TRERF1 | 55809 | 3 | 0 | 17 | |
| TCGA | TRERF1 | 55809 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of TRERF1:
Generating mutation plots.
Highly correlated genes for TRERF1:
Showing top 20/996 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRERF1 | ACTR2 | 0.826128 | 3 | 0 | 3 |
| TRERF1 | FPGT | 0.822293 | 3 | 0 | 3 |
| TRERF1 | RAD23B | 0.798224 | 3 | 0 | 3 |
| TRERF1 | AQR | 0.771852 | 3 | 0 | 3 |
| TRERF1 | TRIP11 | 0.762349 | 3 | 0 | 3 |
| TRERF1 | CCNYL1 | 0.76003 | 5 | 0 | 4 |
| TRERF1 | ACBD3 | 0.757897 | 3 | 0 | 3 |
| TRERF1 | JAK2 | 0.7515 | 5 | 0 | 5 |
| TRERF1 | PLXNA2 | 0.750684 | 3 | 0 | 3 |
| TRERF1 | POLI | 0.745011 | 3 | 0 | 3 |
| TRERF1 | ORMDL2 | 0.743492 | 3 | 0 | 3 |
| TRERF1 | MAP2K1 | 0.743204 | 4 | 0 | 3 |
| TRERF1 | PPIL3 | 0.738536 | 3 | 0 | 3 |
| TRERF1 | PLEKHM1 | 0.733899 | 4 | 0 | 4 |
| TRERF1 | NCOR1 | 0.731809 | 3 | 0 | 3 |
| TRERF1 | UBE2A | 0.729374 | 4 | 0 | 3 |
| TRERF1 | DLG1 | 0.728017 | 4 | 0 | 4 |
| TRERF1 | CNN3 | 0.723015 | 3 | 0 | 3 |
| TRERF1 | CGGBP1 | 0.722252 | 4 | 0 | 3 |
| TRERF1 | CD59 | 0.721121 | 4 | 0 | 4 |
For details and further investigation, click here
