| Full name: reticulon 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 6252 | HGNC ID: HGNC:10467 | Ensembl Gene: ENSG00000139970 | OMIM ID: 600865 |
Expression of RTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN1 | 6252 | 210222_s_at | -0.0673 | 0.9315 | |
| GSE20347 | RTN1 | 6252 | 210222_s_at | 0.0490 | 0.6287 | |
| GSE23400 | RTN1 | 6252 | 203485_at | -0.1915 | 0.0003 | |
| GSE26886 | RTN1 | 6252 | 203485_at | 0.4427 | 0.5981 | |
| GSE29001 | RTN1 | 6252 | 203485_at | 0.3763 | 0.4268 | |
| GSE38129 | RTN1 | 6252 | 210222_s_at | -0.0881 | 0.6181 | |
| GSE45670 | RTN1 | 6252 | 203485_at | -1.1233 | 0.0060 | |
| GSE53622 | RTN1 | 6252 | 43585 | -0.1993 | 0.2542 | |
| GSE53624 | RTN1 | 6252 | 43585 | 0.1337 | 0.4086 | |
| GSE63941 | RTN1 | 6252 | 203485_at | -3.9120 | 0.0016 | |
| GSE77861 | RTN1 | 6252 | 210222_s_at | 0.0728 | 0.5178 | |
| GSE97050 | RTN1 | 6252 | A_23_P140290 | 0.1399 | 0.7236 | |
| SRP064894 | RTN1 | 6252 | RNAseq | 0.7672 | 0.0436 | |
| SRP133303 | RTN1 | 6252 | RNAseq | -0.4151 | 0.1311 | |
| SRP159526 | RTN1 | 6252 | RNAseq | 1.1597 | 0.0223 | |
| SRP193095 | RTN1 | 6252 | RNAseq | 0.0458 | 0.8454 | |
| SRP219564 | RTN1 | 6252 | RNAseq | 0.1071 | 0.8898 | |
| TCGA | RTN1 | 6252 | RNAseq | -0.5173 | 0.0214 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by RTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN1 | 6252 | 8 | 3 | 19 | |
| GSE20123 | RTN1 | 6252 | 7 | 3 | 20 | |
| GSE43470 | RTN1 | 6252 | 8 | 2 | 33 | |
| GSE46452 | RTN1 | 6252 | 16 | 3 | 40 | |
| GSE47630 | RTN1 | 6252 | 11 | 9 | 20 | |
| GSE54993 | RTN1 | 6252 | 3 | 8 | 59 | |
| GSE54994 | RTN1 | 6252 | 19 | 4 | 30 | |
| GSE60625 | RTN1 | 6252 | 0 | 2 | 9 | |
| GSE74703 | RTN1 | 6252 | 7 | 2 | 27 | |
| GSE74704 | RTN1 | 6252 | 3 | 2 | 15 | |
| TCGA | RTN1 | 6252 | 32 | 14 | 50 |
Total number of gains: 114; Total number of losses: 52; Total Number of normals: 322.
Somatic mutations of RTN1:
Generating mutation plots.
Highly correlated genes for RTN1:
Showing top 20/957 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN1 | DZIP1L | 0.76196 | 3 | 0 | 3 |
| RTN1 | TNFSF12 | 0.738296 | 3 | 0 | 3 |
| RTN1 | GPC6 | 0.707147 | 6 | 0 | 6 |
| RTN1 | CNRIP1 | 0.706464 | 6 | 0 | 6 |
| RTN1 | RCOR3 | 0.703154 | 3 | 0 | 3 |
| RTN1 | TBC1D16 | 0.703025 | 4 | 0 | 4 |
| RTN1 | LIX1L | 0.700405 | 6 | 0 | 5 |
| RTN1 | GLIPR2 | 0.6978 | 7 | 0 | 6 |
| RTN1 | TMEM170B | 0.695633 | 6 | 0 | 6 |
| RTN1 | MYEF2 | 0.69493 | 3 | 0 | 3 |
| RTN1 | NRROS | 0.694137 | 5 | 0 | 5 |
| RTN1 | CD163L1 | 0.693157 | 3 | 0 | 3 |
| RTN1 | ARHGEF6 | 0.691311 | 9 | 0 | 8 |
| RTN1 | FZD4 | 0.691252 | 7 | 0 | 7 |
| RTN1 | DIXDC1 | 0.691077 | 8 | 0 | 8 |
| RTN1 | GNG2 | 0.689134 | 6 | 0 | 5 |
| RTN1 | ERC1 | 0.687514 | 3 | 0 | 3 |
| RTN1 | RCSD1 | 0.686076 | 5 | 0 | 5 |
| RTN1 | MCAM | 0.684984 | 7 | 0 | 5 |
| RTN1 | PLEKHO1 | 0.684184 | 9 | 0 | 7 |
For details and further investigation, click here
