| Full name: receptor transporter protein 4 | Alias Symbol: IFRG28|Z3CXXC4 | ||
| Type: protein-coding gene | Cytoband: 3q27.3 | ||
| Entrez ID: 64108 | HGNC ID: HGNC:23992 | Ensembl Gene: ENSG00000136514 | OMIM ID: 609350 |
| Drug and gene relationship at DGIdb | |||
Expression of RTP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTP4 | 64108 | 219684_at | 0.9154 | 0.4072 | |
| GSE20347 | RTP4 | 64108 | 219684_at | 1.0475 | 0.0055 | |
| GSE23400 | RTP4 | 64108 | 219684_at | 0.4375 | 0.0005 | |
| GSE26886 | RTP4 | 64108 | 219684_at | 1.2064 | 0.0347 | |
| GSE29001 | RTP4 | 64108 | 219684_at | 2.0036 | 0.0000 | |
| GSE38129 | RTP4 | 64108 | 219684_at | 1.0513 | 0.0002 | |
| GSE45670 | RTP4 | 64108 | 219684_at | 1.5041 | 0.0063 | |
| GSE53622 | RTP4 | 64108 | 77899 | 0.9885 | 0.0000 | |
| GSE53624 | RTP4 | 64108 | 77899 | 1.3426 | 0.0000 | |
| GSE63941 | RTP4 | 64108 | 219684_at | -1.6994 | 0.2833 | |
| GSE77861 | RTP4 | 64108 | 219684_at | -0.1621 | 0.8026 | |
| GSE97050 | RTP4 | 64108 | A_23_P166797 | 0.6272 | 0.2560 | |
| SRP007169 | RTP4 | 64108 | RNAseq | 3.0324 | 0.0000 | |
| SRP064894 | RTP4 | 64108 | RNAseq | 2.0110 | 0.0000 | |
| SRP133303 | RTP4 | 64108 | RNAseq | 1.6651 | 0.0002 | |
| SRP193095 | RTP4 | 64108 | RNAseq | 1.1086 | 0.0002 | |
| SRP219564 | RTP4 | 64108 | RNAseq | 1.7436 | 0.0158 | |
| TCGA | RTP4 | 64108 | RNAseq | 0.5542 | 0.0167 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by RTP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTP4 | 64108 | 24 | 0 | 6 | |
| GSE20123 | RTP4 | 64108 | 24 | 0 | 6 | |
| GSE43470 | RTP4 | 64108 | 23 | 1 | 19 | |
| GSE46452 | RTP4 | 64108 | 19 | 1 | 39 | |
| GSE47630 | RTP4 | 64108 | 27 | 2 | 11 | |
| GSE54993 | RTP4 | 64108 | 1 | 19 | 50 | |
| GSE54994 | RTP4 | 64108 | 37 | 0 | 16 | |
| GSE60625 | RTP4 | 64108 | 0 | 6 | 5 | |
| GSE74703 | RTP4 | 64108 | 20 | 1 | 15 | |
| GSE74704 | RTP4 | 64108 | 16 | 0 | 4 | |
| TCGA | RTP4 | 64108 | 77 | 0 | 19 |
Total number of gains: 268; Total number of losses: 30; Total Number of normals: 190.
Somatic mutations of RTP4:
Generating mutation plots.
Highly correlated genes for RTP4:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTP4 | LAMP3 | 0.745156 | 11 | 0 | 11 |
| RTP4 | PARP9 | 0.743295 | 9 | 0 | 9 |
| RTP4 | USP41 | 0.733743 | 3 | 0 | 3 |
| RTP4 | SLC35B3 | 0.727351 | 3 | 0 | 3 |
| RTP4 | CCDC97 | 0.724069 | 3 | 0 | 3 |
| RTP4 | HERC5 | 0.723513 | 12 | 0 | 12 |
| RTP4 | PARP14 | 0.718446 | 9 | 0 | 9 |
| RTP4 | DDX60 | 0.704694 | 13 | 0 | 12 |
| RTP4 | PSMB9 | 0.703373 | 12 | 0 | 12 |
| RTP4 | OAS2 | 0.702522 | 12 | 0 | 12 |
| RTP4 | TAP1 | 0.701919 | 11 | 0 | 10 |
| RTP4 | WDR81 | 0.698086 | 3 | 0 | 3 |
| RTP4 | DTX3L | 0.693703 | 9 | 0 | 9 |
| RTP4 | IFIT3 | 0.693565 | 13 | 0 | 13 |
| RTP4 | IFI44 | 0.692692 | 13 | 0 | 12 |
| RTP4 | HNRNPUL1 | 0.69153 | 3 | 0 | 3 |
| RTP4 | BST2 | 0.68826 | 11 | 0 | 10 |
| RTP4 | IFI44L | 0.687643 | 12 | 0 | 11 |
| RTP4 | NMI | 0.68569 | 13 | 0 | 11 |
| RTP4 | FBXO6 | 0.683704 | 7 | 0 | 6 |
For details and further investigation, click here
