| Full name: bone marrow stromal cell antigen 2 | Alias Symbol: CD317|tetherin | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 684 | HGNC ID: HGNC:1119 | Ensembl Gene: ENSG00000130303 | OMIM ID: 600534 |
| Drug and gene relationship at DGIdb | |||
Expression of BST2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BST2 | 684 | 201641_at | 1.1257 | 0.3886 | |
| GSE20347 | BST2 | 684 | 201641_at | 1.0713 | 0.0443 | |
| GSE23400 | BST2 | 684 | 201641_at | 1.1297 | 0.0000 | |
| GSE26886 | BST2 | 684 | 201641_at | 1.2637 | 0.0718 | |
| GSE29001 | BST2 | 684 | 201641_at | 1.7005 | 0.0042 | |
| GSE38129 | BST2 | 684 | 201641_at | 0.8549 | 0.0271 | |
| GSE45670 | BST2 | 684 | 201641_at | 1.9852 | 0.0008 | |
| GSE53622 | BST2 | 684 | 145487 | 1.2129 | 0.0000 | |
| GSE53624 | BST2 | 684 | 69615 | 1.4068 | 0.0000 | |
| GSE63941 | BST2 | 684 | 201641_at | 2.9131 | 0.1024 | |
| GSE77861 | BST2 | 684 | 201641_at | 0.7228 | 0.3125 | |
| GSE97050 | BST2 | 684 | A_33_P3220911 | 0.8884 | 0.1297 | |
| SRP007169 | BST2 | 684 | RNAseq | 2.4996 | 0.0011 | |
| SRP064894 | BST2 | 684 | RNAseq | 2.4076 | 0.0000 | |
| SRP133303 | BST2 | 684 | RNAseq | 1.3310 | 0.0051 | |
| SRP159526 | BST2 | 684 | RNAseq | -0.1659 | 0.8503 | |
| SRP193095 | BST2 | 684 | RNAseq | 1.7120 | 0.0000 | |
| SRP219564 | BST2 | 684 | RNAseq | 0.7096 | 0.3870 | |
| TCGA | BST2 | 684 | RNAseq | 0.4541 | 0.0022 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by BST2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BST2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BST2 | 684 | 4 | 4 | 22 | |
| GSE20123 | BST2 | 684 | 3 | 2 | 25 | |
| GSE43470 | BST2 | 684 | 2 | 6 | 35 | |
| GSE46452 | BST2 | 684 | 47 | 1 | 11 | |
| GSE47630 | BST2 | 684 | 4 | 8 | 28 | |
| GSE54993 | BST2 | 684 | 15 | 4 | 51 | |
| GSE54994 | BST2 | 684 | 6 | 14 | 33 | |
| GSE60625 | BST2 | 684 | 9 | 0 | 2 | |
| GSE74703 | BST2 | 684 | 2 | 4 | 30 | |
| GSE74704 | BST2 | 684 | 0 | 2 | 18 | |
| TCGA | BST2 | 684 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of BST2:
Generating mutation plots.
Highly correlated genes for BST2:
Showing top 20/366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BST2 | RNF213 | 0.792079 | 3 | 0 | 3 |
| BST2 | IFI44 | 0.784699 | 11 | 0 | 11 |
| BST2 | CMPK2 | 0.765896 | 7 | 0 | 6 |
| BST2 | PREX1 | 0.735455 | 3 | 0 | 3 |
| BST2 | USP41 | 0.734795 | 3 | 0 | 3 |
| BST2 | EPSTI1 | 0.734679 | 8 | 0 | 8 |
| BST2 | DDX60L | 0.725617 | 5 | 0 | 5 |
| BST2 | IFI6 | 0.718457 | 12 | 0 | 12 |
| BST2 | OAS2 | 0.707539 | 12 | 0 | 11 |
| BST2 | CASK | 0.702269 | 3 | 0 | 3 |
| BST2 | PARP14 | 0.698338 | 8 | 0 | 7 |
| BST2 | WDR81 | 0.695104 | 3 | 0 | 3 |
| BST2 | PARP9 | 0.694437 | 7 | 0 | 6 |
| BST2 | XAF1 | 0.693621 | 12 | 0 | 11 |
| BST2 | FCGR3A | 0.688335 | 3 | 0 | 3 |
| BST2 | RTP4 | 0.68826 | 11 | 0 | 10 |
| BST2 | DDX60 | 0.687201 | 12 | 0 | 10 |
| BST2 | IFI35 | 0.685871 | 13 | 0 | 12 |
| BST2 | PIK3R3 | 0.685822 | 4 | 0 | 4 |
| BST2 | UBE2L6 | 0.685697 | 12 | 0 | 10 |
For details and further investigation, click here
