| Full name: DExD/H-box helicase 60 | Alias Symbol: FLJ20035 | ||
| Type: protein-coding gene | Cytoband: 4q32.3 | ||
| Entrez ID: 55601 | HGNC ID: HGNC:25942 | Ensembl Gene: ENSG00000137628 | OMIM ID: 613974 |
| Drug and gene relationship at DGIdb | |||
Expression of DDX60:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX60 | 55601 | 218986_s_at | 0.8896 | 0.4238 | |
| GSE20347 | DDX60 | 55601 | 218986_s_at | 1.5322 | 0.0002 | |
| GSE23400 | DDX60 | 55601 | 218986_s_at | 0.9163 | 0.0000 | |
| GSE26886 | DDX60 | 55601 | 218986_s_at | 2.6585 | 0.0001 | |
| GSE29001 | DDX60 | 55601 | 218986_s_at | 2.1319 | 0.0005 | |
| GSE38129 | DDX60 | 55601 | 218986_s_at | 1.1966 | 0.0001 | |
| GSE45670 | DDX60 | 55601 | 218986_s_at | 2.1716 | 0.0001 | |
| GSE53622 | DDX60 | 55601 | 107985 | 1.3911 | 0.0000 | |
| GSE53624 | DDX60 | 55601 | 107985 | 1.5562 | 0.0000 | |
| GSE63941 | DDX60 | 55601 | 218986_s_at | -1.0927 | 0.4927 | |
| GSE77861 | DDX60 | 55601 | 218986_s_at | 1.1122 | 0.1021 | |
| GSE97050 | DDX60 | 55601 | A_23_P41470 | 0.7631 | 0.1791 | |
| SRP007169 | DDX60 | 55601 | RNAseq | 4.1484 | 0.0000 | |
| SRP008496 | DDX60 | 55601 | RNAseq | 3.3046 | 0.0000 | |
| SRP064894 | DDX60 | 55601 | RNAseq | 2.4075 | 0.0000 | |
| SRP133303 | DDX60 | 55601 | RNAseq | 1.9100 | 0.0000 | |
| SRP159526 | DDX60 | 55601 | RNAseq | -0.2501 | 0.6563 | |
| SRP193095 | DDX60 | 55601 | RNAseq | -0.1466 | 0.7432 | |
| SRP219564 | DDX60 | 55601 | RNAseq | 1.2042 | 0.1879 | |
| TCGA | DDX60 | 55601 | RNAseq | 0.1545 | 0.1935 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by DDX60 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX60:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX60 | 55601 | 1 | 11 | 18 | |
| GSE20123 | DDX60 | 55601 | 1 | 11 | 18 | |
| GSE43470 | DDX60 | 55601 | 0 | 13 | 30 | |
| GSE46452 | DDX60 | 55601 | 1 | 36 | 22 | |
| GSE47630 | DDX60 | 55601 | 0 | 22 | 18 | |
| GSE54993 | DDX60 | 55601 | 10 | 0 | 60 | |
| GSE54994 | DDX60 | 55601 | 1 | 13 | 39 | |
| GSE60625 | DDX60 | 55601 | 0 | 0 | 11 | |
| GSE74703 | DDX60 | 55601 | 0 | 11 | 25 | |
| GSE74704 | DDX60 | 55601 | 0 | 5 | 15 | |
| TCGA | DDX60 | 55601 | 12 | 32 | 52 |
Total number of gains: 26; Total number of losses: 154; Total Number of normals: 308.
Somatic mutations of DDX60:
Generating mutation plots.
Highly correlated genes for DDX60:
Showing top 20/1246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX60 | IFI44 | 0.866287 | 13 | 0 | 13 |
| DDX60 | DDX60L | 0.836214 | 7 | 0 | 7 |
| DDX60 | USP41 | 0.809769 | 3 | 0 | 3 |
| DDX60 | IFIT1 | 0.808201 | 13 | 0 | 13 |
| DDX60 | HERC5 | 0.803938 | 12 | 0 | 12 |
| DDX60 | EPSTI1 | 0.800011 | 8 | 0 | 8 |
| DDX60 | IFI44L | 0.789326 | 13 | 0 | 12 |
| DDX60 | IFI6 | 0.785905 | 13 | 0 | 13 |
| DDX60 | IFI35 | 0.78544 | 13 | 0 | 13 |
| DDX60 | IFIT3 | 0.785413 | 13 | 0 | 13 |
| DDX60 | RSAD2 | 0.779201 | 13 | 0 | 13 |
| DDX60 | CD80 | 0.777571 | 3 | 0 | 3 |
| DDX60 | IFIH1 | 0.774653 | 11 | 0 | 11 |
| DDX60 | STAT1 | 0.774373 | 13 | 0 | 13 |
| DDX60 | ISG15 | 0.764296 | 13 | 0 | 12 |
| DDX60 | SP110 | 0.75849 | 12 | 0 | 11 |
| DDX60 | XAF1 | 0.757816 | 13 | 0 | 13 |
| DDX60 | PARP14 | 0.75476 | 9 | 0 | 9 |
| DDX60 | CMPK2 | 0.752264 | 9 | 0 | 7 |
| DDX60 | FCGR3A | 0.745308 | 3 | 0 | 3 |
For details and further investigation, click here
