| Full name: interferon induced protein 44 | Alias Symbol: MTAP44|p44|TLDC5 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 10561 | HGNC ID: HGNC:16938 | Ensembl Gene: ENSG00000137965 | OMIM ID: 610468 |
| Drug and gene relationship at DGIdb | |||
Expression of IFI44:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFI44 | 10561 | 214453_s_at | 0.5943 | 0.6806 | |
| GSE20347 | IFI44 | 10561 | 214453_s_at | 1.6401 | 0.0003 | |
| GSE23400 | IFI44 | 10561 | 214453_s_at | 1.1749 | 0.0000 | |
| GSE26886 | IFI44 | 10561 | 214453_s_at | 1.3743 | 0.0684 | |
| GSE29001 | IFI44 | 10561 | 214453_s_at | 2.2016 | 0.0000 | |
| GSE38129 | IFI44 | 10561 | 214453_s_at | 1.3996 | 0.0001 | |
| GSE45670 | IFI44 | 10561 | 214453_s_at | 1.9104 | 0.0004 | |
| GSE53622 | IFI44 | 10561 | 10016 | 1.1536 | 0.0000 | |
| GSE53624 | IFI44 | 10561 | 10016 | 1.5625 | 0.0000 | |
| GSE63941 | IFI44 | 10561 | 214453_s_at | -1.1202 | 0.5679 | |
| GSE77861 | IFI44 | 10561 | 214453_s_at | 0.5236 | 0.3839 | |
| GSE97050 | IFI44 | 10561 | A_23_P23074 | 0.7540 | 0.2415 | |
| SRP007169 | IFI44 | 10561 | RNAseq | 1.6411 | 0.0082 | |
| SRP008496 | IFI44 | 10561 | RNAseq | 1.4453 | 0.0016 | |
| SRP064894 | IFI44 | 10561 | RNAseq | 2.5331 | 0.0000 | |
| SRP133303 | IFI44 | 10561 | RNAseq | 1.2314 | 0.0009 | |
| SRP159526 | IFI44 | 10561 | RNAseq | -0.9612 | 0.1981 | |
| SRP193095 | IFI44 | 10561 | RNAseq | 1.3475 | 0.0000 | |
| TCGA | IFI44 | 10561 | RNAseq | 0.5052 | 0.0001 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by IFI44 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFI44:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFI44 | 10561 | 0 | 7 | 23 | |
| GSE20123 | IFI44 | 10561 | 0 | 7 | 23 | |
| GSE43470 | IFI44 | 10561 | 4 | 2 | 37 | |
| GSE46452 | IFI44 | 10561 | 0 | 1 | 58 | |
| GSE47630 | IFI44 | 10561 | 8 | 6 | 26 | |
| GSE54993 | IFI44 | 10561 | 0 | 0 | 70 | |
| GSE54994 | IFI44 | 10561 | 6 | 3 | 44 | |
| GSE60625 | IFI44 | 10561 | 0 | 0 | 11 | |
| GSE74703 | IFI44 | 10561 | 3 | 2 | 31 | |
| GSE74704 | IFI44 | 10561 | 0 | 4 | 16 | |
| TCGA | IFI44 | 10561 | 9 | 24 | 63 |
Total number of gains: 30; Total number of losses: 56; Total Number of normals: 402.
Somatic mutations of IFI44:
Generating mutation plots.
Highly correlated genes for IFI44:
Showing top 20/748 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFI44 | IFI44L | 0.872081 | 13 | 0 | 13 |
| IFI44 | DDX60 | 0.866287 | 13 | 0 | 13 |
| IFI44 | USP41 | 0.849057 | 3 | 0 | 3 |
| IFI44 | IFIT1 | 0.839059 | 13 | 0 | 13 |
| IFI44 | EPSTI1 | 0.836333 | 7 | 0 | 7 |
| IFI44 | CMPK2 | 0.829936 | 8 | 0 | 8 |
| IFI44 | RSAD2 | 0.818789 | 13 | 0 | 13 |
| IFI44 | IFIT3 | 0.808665 | 13 | 0 | 13 |
| IFI44 | IFI6 | 0.808509 | 13 | 0 | 11 |
| IFI44 | HERC5 | 0.80378 | 12 | 0 | 12 |
| IFI44 | IFI35 | 0.78747 | 13 | 0 | 13 |
| IFI44 | BST2 | 0.784699 | 11 | 0 | 11 |
| IFI44 | IFIH1 | 0.784274 | 11 | 0 | 11 |
| IFI44 | XAF1 | 0.784144 | 13 | 0 | 13 |
| IFI44 | ISG15 | 0.779686 | 13 | 0 | 13 |
| IFI44 | OAS2 | 0.772733 | 13 | 0 | 12 |
| IFI44 | DDX60L | 0.766297 | 7 | 0 | 7 |
| IFI44 | IFITM1 | 0.745619 | 10 | 0 | 9 |
| IFI44 | UBE2L6 | 0.741857 | 13 | 0 | 13 |
| IFI44 | STAT1 | 0.740043 | 13 | 0 | 12 |
For details and further investigation, click here
