| Full name: 5'-nucleotidase domain containing 2 | Alias Symbol: FLJ12442 | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 64943 | HGNC ID: HGNC:25717 | Ensembl Gene: ENSG00000168268 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NT5DC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NT5DC2 | 64943 | 218051_s_at | 0.4653 | 0.2674 | |
| GSE20347 | NT5DC2 | 64943 | 218051_s_at | -0.6110 | 0.0191 | |
| GSE23400 | NT5DC2 | 64943 | 218051_s_at | -0.4119 | 0.0040 | |
| GSE26886 | NT5DC2 | 64943 | 218051_s_at | -1.2910 | 0.0015 | |
| GSE29001 | NT5DC2 | 64943 | 218051_s_at | -1.1394 | 0.0051 | |
| GSE38129 | NT5DC2 | 64943 | 218051_s_at | -0.2091 | 0.3945 | |
| GSE45670 | NT5DC2 | 64943 | 218051_s_at | -0.2517 | 0.2341 | |
| GSE53622 | NT5DC2 | 64943 | 1126 | -0.5677 | 0.0000 | |
| GSE53624 | NT5DC2 | 64943 | 1126 | -0.6412 | 0.0000 | |
| GSE63941 | NT5DC2 | 64943 | 218051_s_at | 2.2272 | 0.0015 | |
| GSE77861 | NT5DC2 | 64943 | 218051_s_at | -0.9001 | 0.0434 | |
| GSE97050 | NT5DC2 | 64943 | A_23_P44836 | -0.2462 | 0.5203 | |
| SRP007169 | NT5DC2 | 64943 | RNAseq | -1.9428 | 0.0000 | |
| SRP008496 | NT5DC2 | 64943 | RNAseq | -1.4570 | 0.0000 | |
| SRP064894 | NT5DC2 | 64943 | RNAseq | -0.2087 | 0.4480 | |
| SRP133303 | NT5DC2 | 64943 | RNAseq | -0.5897 | 0.0133 | |
| SRP159526 | NT5DC2 | 64943 | RNAseq | 0.0782 | 0.8709 | |
| SRP193095 | NT5DC2 | 64943 | RNAseq | -0.5565 | 0.0122 | |
| SRP219564 | NT5DC2 | 64943 | RNAseq | -0.6018 | 0.2123 | |
| TCGA | NT5DC2 | 64943 | RNAseq | 0.2751 | 0.0006 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by NT5DC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NT5DC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NT5DC2 | 64943 | 0 | 18 | 12 | |
| GSE20123 | NT5DC2 | 64943 | 0 | 19 | 11 | |
| GSE43470 | NT5DC2 | 64943 | 0 | 18 | 25 | |
| GSE46452 | NT5DC2 | 64943 | 2 | 17 | 40 | |
| GSE47630 | NT5DC2 | 64943 | 1 | 24 | 15 | |
| GSE54993 | NT5DC2 | 64943 | 6 | 2 | 62 | |
| GSE54994 | NT5DC2 | 64943 | 0 | 33 | 20 | |
| GSE60625 | NT5DC2 | 64943 | 5 | 0 | 6 | |
| GSE74703 | NT5DC2 | 64943 | 0 | 14 | 22 | |
| GSE74704 | NT5DC2 | 64943 | 0 | 12 | 8 | |
| TCGA | NT5DC2 | 64943 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of NT5DC2:
Generating mutation plots.
Highly correlated genes for NT5DC2:
Showing top 20/378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NT5DC2 | KIAA1522 | 0.775359 | 3 | 0 | 3 |
| NT5DC2 | MSH2 | 0.749899 | 3 | 0 | 3 |
| NT5DC2 | KRI1 | 0.721604 | 3 | 0 | 3 |
| NT5DC2 | MRPL35 | 0.720091 | 3 | 0 | 3 |
| NT5DC2 | RWDD2B | 0.716461 | 3 | 0 | 3 |
| NT5DC2 | MEN1 | 0.714328 | 3 | 0 | 3 |
| NT5DC2 | MCU | 0.710066 | 3 | 0 | 3 |
| NT5DC2 | RTN4R | 0.693245 | 3 | 0 | 3 |
| NT5DC2 | MOGS | 0.693014 | 3 | 0 | 3 |
| NT5DC2 | DNAJC9 | 0.691018 | 3 | 0 | 3 |
| NT5DC2 | CLPTM1 | 0.681685 | 4 | 0 | 3 |
| NT5DC2 | MRPL13 | 0.679413 | 3 | 0 | 3 |
| NT5DC2 | LSR | 0.676695 | 3 | 0 | 3 |
| NT5DC2 | PRELID1 | 0.674138 | 5 | 0 | 5 |
| NT5DC2 | GLRX3 | 0.67337 | 3 | 0 | 3 |
| NT5DC2 | SLC25A39 | 0.67283 | 5 | 0 | 4 |
| NT5DC2 | AASDHPPT | 0.671134 | 3 | 0 | 3 |
| NT5DC2 | RPS6KA4 | 0.669679 | 3 | 0 | 3 |
| NT5DC2 | TINCR | 0.6628 | 3 | 0 | 3 |
| NT5DC2 | PSMC4 | 0.662218 | 3 | 0 | 3 |
For details and further investigation, click here
