| Full name: single stranded DNA binding protein 1 | Alias Symbol: SSBP|mtSSB | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 6742 | HGNC ID: HGNC:11317 | Ensembl Gene: ENSG00000106028 | OMIM ID: 600439 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SSBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSBP1 | 6742 | 202591_s_at | -0.1209 | 0.7739 | |
| GSE20347 | SSBP1 | 6742 | 202591_s_at | 0.1066 | 0.4918 | |
| GSE23400 | SSBP1 | 6742 | 202591_s_at | 0.3468 | 0.0002 | |
| GSE26886 | SSBP1 | 6742 | 202591_s_at | -0.7667 | 0.0007 | |
| GSE29001 | SSBP1 | 6742 | 202591_s_at | 0.0906 | 0.8565 | |
| GSE38129 | SSBP1 | 6742 | 202591_s_at | 0.2700 | 0.0054 | |
| GSE45670 | SSBP1 | 6742 | 202591_s_at | 0.0668 | 0.6742 | |
| GSE53622 | SSBP1 | 6742 | 41875 | 0.0953 | 0.1348 | |
| GSE53624 | SSBP1 | 6742 | 41875 | 0.4781 | 0.0000 | |
| GSE63941 | SSBP1 | 6742 | 202591_s_at | 0.1477 | 0.7222 | |
| GSE77861 | SSBP1 | 6742 | 202591_s_at | -0.0310 | 0.8739 | |
| GSE97050 | SSBP1 | 6742 | A_23_P31536 | 0.0137 | 0.9609 | |
| SRP007169 | SSBP1 | 6742 | RNAseq | 0.5435 | 0.1893 | |
| SRP008496 | SSBP1 | 6742 | RNAseq | 0.3694 | 0.2625 | |
| SRP064894 | SSBP1 | 6742 | RNAseq | 0.1321 | 0.5220 | |
| SRP133303 | SSBP1 | 6742 | RNAseq | 0.1761 | 0.2426 | |
| SRP159526 | SSBP1 | 6742 | RNAseq | -0.2212 | 0.3169 | |
| SRP193095 | SSBP1 | 6742 | RNAseq | -0.3881 | 0.0090 | |
| SRP219564 | SSBP1 | 6742 | RNAseq | -0.3618 | 0.1585 | |
| TCGA | SSBP1 | 6742 | RNAseq | 0.1143 | 0.0406 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SSBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSBP1 | 6742 | 5 | 2 | 23 | |
| GSE20123 | SSBP1 | 6742 | 5 | 2 | 23 | |
| GSE43470 | SSBP1 | 6742 | 2 | 4 | 37 | |
| GSE46452 | SSBP1 | 6742 | 7 | 2 | 50 | |
| GSE47630 | SSBP1 | 6742 | 6 | 7 | 27 | |
| GSE54993 | SSBP1 | 6742 | 3 | 5 | 62 | |
| GSE54994 | SSBP1 | 6742 | 5 | 8 | 40 | |
| GSE60625 | SSBP1 | 6742 | 0 | 0 | 11 | |
| GSE74703 | SSBP1 | 6742 | 2 | 4 | 30 | |
| GSE74704 | SSBP1 | 6742 | 1 | 2 | 17 | |
| TCGA | SSBP1 | 6742 | 29 | 23 | 44 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of SSBP1:
Generating mutation plots.
Highly correlated genes for SSBP1:
Showing top 20/431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSBP1 | POLR2L | 0.838274 | 3 | 0 | 3 |
| SSBP1 | RWDD2B | 0.766803 | 3 | 0 | 3 |
| SSBP1 | HEATR5A | 0.737259 | 3 | 0 | 3 |
| SSBP1 | VAMP5 | 0.730745 | 3 | 0 | 3 |
| SSBP1 | MFSD5 | 0.727958 | 3 | 0 | 3 |
| SSBP1 | KCTD1 | 0.727291 | 3 | 0 | 3 |
| SSBP1 | PRADC1 | 0.724971 | 3 | 0 | 3 |
| SSBP1 | CHCHD1 | 0.719837 | 5 | 0 | 5 |
| SSBP1 | SDHD | 0.711213 | 4 | 0 | 4 |
| SSBP1 | TBCA | 0.707022 | 3 | 0 | 3 |
| SSBP1 | TMEM120A | 0.695822 | 3 | 0 | 3 |
| SSBP1 | BARD1 | 0.690729 | 3 | 0 | 3 |
| SSBP1 | KLHL20 | 0.689277 | 3 | 0 | 3 |
| SSBP1 | SACM1L | 0.686768 | 3 | 0 | 3 |
| SSBP1 | RAB3D | 0.68501 | 3 | 0 | 3 |
| SSBP1 | HMGN1 | 0.682466 | 4 | 0 | 3 |
| SSBP1 | RAB21 | 0.680566 | 4 | 0 | 3 |
| SSBP1 | ZNF543 | 0.675895 | 3 | 0 | 3 |
| SSBP1 | TMEM167B | 0.675804 | 3 | 0 | 3 |
| SSBP1 | PITHD1 | 0.675759 | 3 | 0 | 3 |
For details and further investigation, click here
