| Full name: tripartite motif containing 23 | Alias Symbol: ARD1|RNF46 | ||
| Type: protein-coding gene | Cytoband: 5q12.3 | ||
| Entrez ID: 373 | HGNC ID: HGNC:660 | Ensembl Gene: ENSG00000113595 | OMIM ID: 601747 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM23 | 373 | 204732_s_at | -0.1151 | 0.8751 | |
| GSE20347 | TRIM23 | 373 | 204732_s_at | -0.2257 | 0.2496 | |
| GSE23400 | TRIM23 | 373 | 210995_s_at | -0.1193 | 0.0000 | |
| GSE26886 | TRIM23 | 373 | 204732_s_at | -1.2171 | 0.0001 | |
| GSE29001 | TRIM23 | 373 | 204732_s_at | -0.1107 | 0.8252 | |
| GSE38129 | TRIM23 | 373 | 204732_s_at | -0.3162 | 0.0975 | |
| GSE45670 | TRIM23 | 373 | 204732_s_at | -0.3134 | 0.0836 | |
| GSE53622 | TRIM23 | 373 | 155469 | -0.6873 | 0.0000 | |
| GSE53624 | TRIM23 | 373 | 155469 | -0.3094 | 0.0015 | |
| GSE63941 | TRIM23 | 373 | 204732_s_at | -2.2547 | 0.0007 | |
| GSE77861 | TRIM23 | 373 | 210994_x_at | -0.1891 | 0.2273 | |
| GSE97050 | TRIM23 | 373 | A_24_P208998 | -0.3514 | 0.1934 | |
| SRP007169 | TRIM23 | 373 | RNAseq | -0.8216 | 0.0222 | |
| SRP008496 | TRIM23 | 373 | RNAseq | -0.9173 | 0.0000 | |
| SRP064894 | TRIM23 | 373 | RNAseq | -0.4084 | 0.0632 | |
| SRP133303 | TRIM23 | 373 | RNAseq | -0.2536 | 0.1558 | |
| SRP159526 | TRIM23 | 373 | RNAseq | -0.4493 | 0.1149 | |
| SRP193095 | TRIM23 | 373 | RNAseq | -0.4370 | 0.0000 | |
| SRP219564 | TRIM23 | 373 | RNAseq | -0.5522 | 0.0171 | |
| TCGA | TRIM23 | 373 | RNAseq | -0.2047 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TRIM23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM23 | 373 | 0 | 13 | 17 | |
| GSE20123 | TRIM23 | 373 | 0 | 13 | 17 | |
| GSE43470 | TRIM23 | 373 | 1 | 13 | 29 | |
| GSE46452 | TRIM23 | 373 | 0 | 28 | 31 | |
| GSE47630 | TRIM23 | 373 | 2 | 17 | 21 | |
| GSE54993 | TRIM23 | 373 | 8 | 1 | 61 | |
| GSE54994 | TRIM23 | 373 | 1 | 19 | 33 | |
| GSE60625 | TRIM23 | 373 | 0 | 0 | 11 | |
| GSE74703 | TRIM23 | 373 | 1 | 9 | 26 | |
| GSE74704 | TRIM23 | 373 | 0 | 6 | 14 | |
| TCGA | TRIM23 | 373 | 3 | 50 | 43 |
Total number of gains: 16; Total number of losses: 169; Total Number of normals: 303.
Somatic mutations of TRIM23:
Generating mutation plots.
Highly correlated genes for TRIM23:
Showing top 20/743 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM23 | CNST | 0.792372 | 3 | 0 | 3 |
| TRIM23 | TBC1D20 | 0.781168 | 3 | 0 | 3 |
| TRIM23 | THAP2 | 0.780162 | 3 | 0 | 3 |
| TRIM23 | FAM160B1 | 0.767843 | 3 | 0 | 3 |
| TRIM23 | IMPACT | 0.753328 | 3 | 0 | 3 |
| TRIM23 | ZFP3 | 0.750514 | 3 | 0 | 3 |
| TRIM23 | HDAC3 | 0.746404 | 3 | 0 | 3 |
| TRIM23 | SGIP1 | 0.743911 | 3 | 0 | 3 |
| TRIM23 | MRC2 | 0.741728 | 3 | 0 | 3 |
| TRIM23 | EXOC4 | 0.740455 | 3 | 0 | 3 |
| TRIM23 | STXBP5 | 0.739932 | 3 | 0 | 3 |
| TRIM23 | NAA20 | 0.736079 | 3 | 0 | 3 |
| TRIM23 | ABLIM2 | 0.735874 | 3 | 0 | 3 |
| TRIM23 | PKN2 | 0.733202 | 4 | 0 | 4 |
| TRIM23 | OSTF1 | 0.733196 | 3 | 0 | 3 |
| TRIM23 | MAP2K1 | 0.731634 | 3 | 0 | 3 |
| TRIM23 | ST6GALNAC6 | 0.729977 | 3 | 0 | 3 |
| TRIM23 | EPG5 | 0.725753 | 4 | 0 | 4 |
| TRIM23 | REST | 0.725599 | 3 | 0 | 3 |
| TRIM23 | NKAPL | 0.724231 | 4 | 0 | 4 |
For details and further investigation, click here
