| Full name: RNA binding fox-1 homolog 2 | Alias Symbol: HNRBP2|FOX-2|HRNBP2 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 23543 | HGNC ID: HGNC:9906 | Ensembl Gene: ENSG00000100320 | OMIM ID: 612149 |
| Drug and gene relationship at DGIdb | |||
Expression of RBFOX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBFOX2 | 23543 | 212104_s_at | -0.3140 | 0.4581 | |
| GSE20347 | RBFOX2 | 23543 | 212104_s_at | -0.0948 | 0.3748 | |
| GSE23400 | RBFOX2 | 23543 | 216215_s_at | -0.0469 | 0.5390 | |
| GSE26886 | RBFOX2 | 23543 | 212104_s_at | -0.5059 | 0.0142 | |
| GSE29001 | RBFOX2 | 23543 | 212104_s_at | -0.2138 | 0.5506 | |
| GSE38129 | RBFOX2 | 23543 | 212104_s_at | -0.1592 | 0.1950 | |
| GSE45670 | RBFOX2 | 23543 | 212104_s_at | -0.0192 | 0.9290 | |
| GSE53622 | RBFOX2 | 23543 | 82184 | -0.1922 | 0.0108 | |
| GSE53624 | RBFOX2 | 23543 | 82184 | -0.2656 | 0.0000 | |
| GSE63941 | RBFOX2 | 23543 | 212104_s_at | -0.6228 | 0.1354 | |
| GSE77861 | RBFOX2 | 23543 | 212104_s_at | 0.2719 | 0.3421 | |
| GSE97050 | RBFOX2 | 23543 | A_23_P103099 | -0.6789 | 0.0781 | |
| SRP007169 | RBFOX2 | 23543 | RNAseq | 0.0647 | 0.8308 | |
| SRP008496 | RBFOX2 | 23543 | RNAseq | 0.3973 | 0.0795 | |
| SRP064894 | RBFOX2 | 23543 | RNAseq | 0.0099 | 0.9616 | |
| SRP133303 | RBFOX2 | 23543 | RNAseq | -0.0883 | 0.5566 | |
| SRP159526 | RBFOX2 | 23543 | RNAseq | -0.2069 | 0.3145 | |
| SRP193095 | RBFOX2 | 23543 | RNAseq | 0.0788 | 0.4947 | |
| SRP219564 | RBFOX2 | 23543 | RNAseq | -0.1233 | 0.7761 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBFOX2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RBFOX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBFOX2 | 23543 | 4 | 6 | 20 | |
| GSE20123 | RBFOX2 | 23543 | 4 | 5 | 21 | |
| GSE43470 | RBFOX2 | 23543 | 4 | 7 | 32 | |
| GSE46452 | RBFOX2 | 23543 | 31 | 1 | 27 | |
| GSE47630 | RBFOX2 | 23543 | 8 | 5 | 27 | |
| GSE54993 | RBFOX2 | 23543 | 3 | 6 | 61 | |
| GSE54994 | RBFOX2 | 23543 | 9 | 9 | 35 | |
| GSE60625 | RBFOX2 | 23543 | 5 | 0 | 6 | |
| GSE74703 | RBFOX2 | 23543 | 4 | 5 | 27 | |
| GSE74704 | RBFOX2 | 23543 | 1 | 2 | 17 | |
| TCGA | RBFOX2 | 23543 | 27 | 15 | 54 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of RBFOX2:
Generating mutation plots.
Highly correlated genes for RBFOX2:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBFOX2 | ARHGEF25 | 0.701345 | 3 | 0 | 3 |
| RBFOX2 | RYBP | 0.701272 | 3 | 0 | 3 |
| RBFOX2 | FAM83D | 0.692602 | 3 | 0 | 3 |
| RBFOX2 | AMOTL1 | 0.689628 | 4 | 0 | 4 |
| RBFOX2 | RASSF3 | 0.689044 | 3 | 0 | 3 |
| RBFOX2 | C5orf24 | 0.688713 | 3 | 0 | 3 |
| RBFOX2 | FBXO30 | 0.68341 | 4 | 0 | 4 |
| RBFOX2 | MAGI1 | 0.682942 | 4 | 0 | 4 |
| RBFOX2 | PRKAA2 | 0.681174 | 3 | 0 | 3 |
| RBFOX2 | PRKG2 | 0.680835 | 3 | 0 | 3 |
| RBFOX2 | U2AF1 | 0.666192 | 3 | 0 | 3 |
| RBFOX2 | ASB5 | 0.662665 | 4 | 0 | 3 |
| RBFOX2 | DAAM2 | 0.65988 | 4 | 0 | 3 |
| RBFOX2 | SRRM2 | 0.657986 | 3 | 0 | 3 |
| RBFOX2 | PURA | 0.656492 | 4 | 0 | 4 |
| RBFOX2 | STARD9 | 0.65622 | 4 | 0 | 3 |
| RBFOX2 | RRAS | 0.654928 | 5 | 0 | 5 |
| RBFOX2 | EPB41L2 | 0.653672 | 4 | 0 | 3 |
| RBFOX2 | PDLIM7 | 0.65182 | 6 | 0 | 5 |
| RBFOX2 | SERTAD1 | 0.646258 | 5 | 0 | 5 |
For details and further investigation, click here
