| Full name: proline rich nuclear receptor coactivator 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 55629 | HGNC ID: HGNC:23158 | Ensembl Gene: ENSG00000189266 | OMIM ID: 611882 |
| Drug and gene relationship at DGIdb | |||
Expression of PNRC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNRC2 | 55629 | 217779_s_at | -0.2819 | 0.5137 | |
| GSE20347 | PNRC2 | 55629 | 217779_s_at | -0.2605 | 0.0702 | |
| GSE23400 | PNRC2 | 55629 | 217779_s_at | -0.1335 | 0.0636 | |
| GSE26886 | PNRC2 | 55629 | 217779_s_at | -0.9306 | 0.0000 | |
| GSE29001 | PNRC2 | 55629 | 217779_s_at | 0.0917 | 0.7134 | |
| GSE38129 | PNRC2 | 55629 | 217779_s_at | -0.4622 | 0.0001 | |
| GSE45670 | PNRC2 | 55629 | 217779_s_at | -0.1438 | 0.2972 | |
| GSE53622 | PNRC2 | 55629 | 16263 | -0.3179 | 0.0000 | |
| GSE53624 | PNRC2 | 55629 | 16263 | -0.3096 | 0.0000 | |
| GSE63941 | PNRC2 | 55629 | 217779_s_at | -0.3017 | 0.2948 | |
| GSE77861 | PNRC2 | 55629 | 217779_s_at | -0.6516 | 0.0026 | |
| GSE97050 | PNRC2 | 55629 | A_23_P103201 | -0.4457 | 0.1698 | |
| SRP007169 | PNRC2 | 55629 | RNAseq | 0.1125 | 0.8301 | |
| SRP008496 | PNRC2 | 55629 | RNAseq | -0.0065 | 0.9830 | |
| SRP064894 | PNRC2 | 55629 | RNAseq | -0.1846 | 0.2544 | |
| SRP133303 | PNRC2 | 55629 | RNAseq | -0.0794 | 0.5237 | |
| SRP159526 | PNRC2 | 55629 | RNAseq | -0.2353 | 0.4991 | |
| SRP193095 | PNRC2 | 55629 | RNAseq | -0.6685 | 0.0000 | |
| SRP219564 | PNRC2 | 55629 | RNAseq | -0.4156 | 0.0731 | |
| TCGA | PNRC2 | 55629 | RNAseq | -0.1721 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PNRC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNRC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNRC2 | 55629 | 0 | 5 | 25 | |
| GSE20123 | PNRC2 | 55629 | 0 | 4 | 26 | |
| GSE43470 | PNRC2 | 55629 | 2 | 6 | 35 | |
| GSE46452 | PNRC2 | 55629 | 5 | 1 | 53 | |
| GSE47630 | PNRC2 | 55629 | 8 | 3 | 29 | |
| GSE54993 | PNRC2 | 55629 | 2 | 1 | 67 | |
| GSE54994 | PNRC2 | 55629 | 11 | 4 | 38 | |
| GSE60625 | PNRC2 | 55629 | 0 | 0 | 11 | |
| GSE74703 | PNRC2 | 55629 | 1 | 4 | 31 | |
| GSE74704 | PNRC2 | 55629 | 0 | 0 | 20 | |
| TCGA | PNRC2 | 55629 | 9 | 24 | 63 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of PNRC2:
Generating mutation plots.
Highly correlated genes for PNRC2:
Showing top 20/956 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNRC2 | FAM83D | 0.77191 | 4 | 0 | 4 |
| PNRC2 | PLEKHB1 | 0.761654 | 3 | 0 | 3 |
| PNRC2 | SAMD8 | 0.750065 | 3 | 0 | 3 |
| PNRC2 | C2CD2 | 0.749118 | 3 | 0 | 3 |
| PNRC2 | EMP2 | 0.748043 | 3 | 0 | 3 |
| PNRC2 | THAP2 | 0.739191 | 4 | 0 | 4 |
| PNRC2 | BRWD3 | 0.739149 | 3 | 0 | 3 |
| PNRC2 | RSRC2 | 0.729516 | 4 | 0 | 3 |
| PNRC2 | IMPA1 | 0.729025 | 3 | 0 | 3 |
| PNRC2 | HDHD2 | 0.727506 | 5 | 0 | 5 |
| PNRC2 | TMEM234 | 0.722935 | 4 | 0 | 4 |
| PNRC2 | CYP4V2 | 0.720457 | 3 | 0 | 3 |
| PNRC2 | NUB1 | 0.719099 | 3 | 0 | 3 |
| PNRC2 | NLRX1 | 0.717263 | 3 | 0 | 3 |
| PNRC2 | HSD17B10 | 0.71436 | 3 | 0 | 3 |
| PNRC2 | DLG1 | 0.710142 | 3 | 0 | 3 |
| PNRC2 | RERG | 0.70919 | 3 | 0 | 3 |
| PNRC2 | MLYCD | 0.706343 | 3 | 0 | 3 |
| PNRC2 | PLD1 | 0.703401 | 3 | 0 | 3 |
| PNRC2 | ZDHHC21 | 0.701537 | 3 | 0 | 3 |
For details and further investigation, click here
