| Full name: SAS-6 centriolar assembly protein | Alias Symbol: DKFZp761A078|SAS-6|FLJ22097|SAS6 | ||
| Type: protein-coding gene | Cytoband: 1p21.2 | ||
| Entrez ID: 163786 | HGNC ID: HGNC:25403 | Ensembl Gene: ENSG00000156876 | OMIM ID: 609321 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SASS6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SASS6 | 163786 | 231895_at | 0.8102 | 0.1026 | |
| GSE26886 | SASS6 | 163786 | 231895_at | 0.5943 | 0.0211 | |
| GSE45670 | SASS6 | 163786 | 231895_at | 0.4812 | 0.0018 | |
| GSE53622 | SASS6 | 163786 | 64384 | 0.7347 | 0.0000 | |
| GSE53624 | SASS6 | 163786 | 64384 | 0.9553 | 0.0000 | |
| GSE63941 | SASS6 | 163786 | 231895_at | 1.3111 | 0.0098 | |
| GSE77861 | SASS6 | 163786 | 231895_at | 0.2062 | 0.2196 | |
| GSE97050 | SASS6 | 163786 | A_24_P349151 | 0.4385 | 0.2179 | |
| SRP007169 | SASS6 | 163786 | RNAseq | 1.5258 | 0.0048 | |
| SRP008496 | SASS6 | 163786 | RNAseq | 1.3565 | 0.0004 | |
| SRP064894 | SASS6 | 163786 | RNAseq | 1.0441 | 0.0005 | |
| SRP133303 | SASS6 | 163786 | RNAseq | 0.8568 | 0.0000 | |
| SRP159526 | SASS6 | 163786 | RNAseq | 0.4625 | 0.1262 | |
| SRP193095 | SASS6 | 163786 | RNAseq | 0.5120 | 0.0000 | |
| SRP219564 | SASS6 | 163786 | RNAseq | 0.5939 | 0.2525 | |
| TCGA | SASS6 | 163786 | RNAseq | 0.4954 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SASS6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SASS6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SASS6 | 163786 | 0 | 10 | 20 | |
| GSE20123 | SASS6 | 163786 | 0 | 10 | 20 | |
| GSE43470 | SASS6 | 163786 | 2 | 6 | 35 | |
| GSE46452 | SASS6 | 163786 | 1 | 1 | 57 | |
| GSE47630 | SASS6 | 163786 | 9 | 5 | 26 | |
| GSE54993 | SASS6 | 163786 | 0 | 1 | 69 | |
| GSE54994 | SASS6 | 163786 | 6 | 3 | 44 | |
| GSE60625 | SASS6 | 163786 | 0 | 0 | 11 | |
| GSE74703 | SASS6 | 163786 | 1 | 5 | 30 | |
| GSE74704 | SASS6 | 163786 | 0 | 6 | 14 | |
| TCGA | SASS6 | 163786 | 8 | 25 | 63 |
Total number of gains: 27; Total number of losses: 72; Total Number of normals: 389.
Somatic mutations of SASS6:
Generating mutation plots.
Highly correlated genes for SASS6:
Showing top 20/1559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SASS6 | LRIF1 | 0.794418 | 3 | 0 | 3 |
| SASS6 | RNF26 | 0.783439 | 3 | 0 | 3 |
| SASS6 | SCNM1 | 0.774357 | 3 | 0 | 3 |
| SASS6 | MMP15 | 0.76108 | 4 | 0 | 3 |
| SASS6 | MMS22L | 0.755795 | 3 | 0 | 3 |
| SASS6 | ORC1 | 0.753351 | 6 | 0 | 6 |
| SASS6 | CREB5 | 0.75241 | 3 | 0 | 3 |
| SASS6 | PTCD1 | 0.751313 | 3 | 0 | 3 |
| SASS6 | EBNA1BP2 | 0.751271 | 3 | 0 | 3 |
| SASS6 | MIS18A | 0.743888 | 6 | 0 | 6 |
| SASS6 | KIF15 | 0.740653 | 7 | 0 | 7 |
| SASS6 | MRPL38 | 0.739969 | 3 | 0 | 3 |
| SASS6 | PYCR2 | 0.739283 | 3 | 0 | 3 |
| SASS6 | SLC25A24 | 0.73833 | 4 | 0 | 4 |
| SASS6 | ZNF707 | 0.732786 | 3 | 0 | 3 |
| SASS6 | NEDD1 | 0.73261 | 7 | 0 | 7 |
| SASS6 | MED1 | 0.732385 | 4 | 0 | 4 |
| SASS6 | SPDL1 | 0.73077 | 5 | 0 | 5 |
| SASS6 | PTPMT1 | 0.729179 | 3 | 0 | 3 |
| SASS6 | PMS2 | 0.728626 | 3 | 0 | 3 |
For details and further investigation, click here
