| Full name: SUB1 regulator of transcription | Alias Symbol: PC4|p15|p14 | ||
| Type: protein-coding gene | Cytoband: 5p13.3 | ||
| Entrez ID: 10923 | HGNC ID: HGNC:19985 | Ensembl Gene: ENSG00000113387 | OMIM ID: 600503 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SUB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUB1 | 10923 | 212857_x_at | 0.1309 | 0.6520 | |
| GSE20347 | SUB1 | 10923 | 212857_x_at | 0.1684 | 0.0321 | |
| GSE23400 | SUB1 | 10923 | 212857_x_at | 0.1704 | 0.0251 | |
| GSE26886 | SUB1 | 10923 | 212857_x_at | 0.8219 | 0.0001 | |
| GSE29001 | SUB1 | 10923 | 212857_x_at | 0.0189 | 0.9319 | |
| GSE38129 | SUB1 | 10923 | 212857_x_at | 0.2278 | 0.0097 | |
| GSE45670 | SUB1 | 10923 | 212857_x_at | 0.4129 | 0.0002 | |
| GSE53622 | SUB1 | 10923 | 129947 | 0.2551 | 0.0000 | |
| GSE53624 | SUB1 | 10923 | 129947 | 0.4918 | 0.0000 | |
| GSE63941 | SUB1 | 10923 | 212857_x_at | 0.0642 | 0.7365 | |
| GSE77861 | SUB1 | 10923 | 212857_x_at | -0.0728 | 0.7417 | |
| GSE97050 | SUB1 | 10923 | A_24_P320328 | 0.3581 | 0.2272 | |
| SRP007169 | SUB1 | 10923 | RNAseq | -0.3075 | 0.4225 | |
| SRP008496 | SUB1 | 10923 | RNAseq | -0.3062 | 0.2183 | |
| SRP064894 | SUB1 | 10923 | RNAseq | -0.0949 | 0.5215 | |
| SRP133303 | SUB1 | 10923 | RNAseq | 0.2632 | 0.0845 | |
| SRP159526 | SUB1 | 10923 | RNAseq | 0.3451 | 0.4095 | |
| SRP193095 | SUB1 | 10923 | RNAseq | -0.3537 | 0.0351 | |
| SRP219564 | SUB1 | 10923 | RNAseq | -0.3336 | 0.1376 | |
| TCGA | SUB1 | 10923 | RNAseq | 0.0817 | 0.0826 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUB1 | 10923 | 11 | 0 | 19 | |
| GSE20123 | SUB1 | 10923 | 11 | 0 | 19 | |
| GSE43470 | SUB1 | 10923 | 15 | 3 | 25 | |
| GSE46452 | SUB1 | 10923 | 6 | 21 | 32 | |
| GSE47630 | SUB1 | 10923 | 6 | 12 | 22 | |
| GSE54993 | SUB1 | 10923 | 5 | 4 | 61 | |
| GSE54994 | SUB1 | 10923 | 26 | 2 | 25 | |
| GSE60625 | SUB1 | 10923 | 0 | 0 | 11 | |
| GSE74703 | SUB1 | 10923 | 12 | 2 | 22 | |
| GSE74704 | SUB1 | 10923 | 10 | 0 | 10 | |
| TCGA | SUB1 | 10923 | 51 | 6 | 39 |
Total number of gains: 153; Total number of losses: 50; Total Number of normals: 285.
Somatic mutations of SUB1:
Generating mutation plots.
Highly correlated genes for SUB1:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUB1 | MRPL1 | 0.751119 | 3 | 0 | 3 |
| SUB1 | TPP2 | 0.742064 | 3 | 0 | 3 |
| SUB1 | PARP8 | 0.738009 | 3 | 0 | 3 |
| SUB1 | RSRC1 | 0.721887 | 4 | 0 | 4 |
| SUB1 | MAPK6 | 0.718259 | 3 | 0 | 3 |
| SUB1 | SCFD1 | 0.715303 | 3 | 0 | 3 |
| SUB1 | MARK3 | 0.711077 | 3 | 0 | 3 |
| SUB1 | WDR81 | 0.702873 | 3 | 0 | 3 |
| SUB1 | SREK1IP1 | 0.701263 | 3 | 0 | 3 |
| SUB1 | USP3 | 0.699518 | 3 | 0 | 3 |
| SUB1 | AP3S1 | 0.696841 | 3 | 0 | 3 |
| SUB1 | ANAPC4 | 0.693819 | 3 | 0 | 3 |
| SUB1 | MTFR2 | 0.68964 | 3 | 0 | 3 |
| SUB1 | NPHP3 | 0.685149 | 3 | 0 | 3 |
| SUB1 | SLC25A37 | 0.684033 | 4 | 0 | 4 |
| SUB1 | MEF2A | 0.681904 | 4 | 0 | 4 |
| SUB1 | CCT6A | 0.681312 | 4 | 0 | 4 |
| SUB1 | PDIA3 | 0.680502 | 4 | 0 | 3 |
| SUB1 | CHST15 | 0.679933 | 4 | 0 | 3 |
| SUB1 | CWC27 | 0.675717 | 3 | 0 | 3 |
For details and further investigation, click here
