| Full name: serine/threonine kinase 19 | Alias Symbol: D6S60|G11|RP1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 8859 | HGNC ID: HGNC:11398 | Ensembl Gene: ENSG00000204344 | OMIM ID: 604977 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of STK19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK19 | 8859 | 204090_at | -0.3715 | 0.4562 | |
| GSE20347 | STK19 | 8859 | 204090_at | -0.8133 | 0.0000 | |
| GSE23400 | STK19 | 8859 | 36019_at | -0.2442 | 0.0000 | |
| GSE26886 | STK19 | 8859 | 204090_at | -0.6416 | 0.0022 | |
| GSE29001 | STK19 | 8859 | 204090_at | -0.3213 | 0.3118 | |
| GSE38129 | STK19 | 8859 | 204090_at | -0.5507 | 0.0001 | |
| GSE45670 | STK19 | 8859 | 36019_at | -0.2954 | 0.0195 | |
| GSE53622 | STK19 | 8859 | 9602 | 0.0531 | 0.8303 | |
| GSE53624 | STK19 | 8859 | 47855 | -0.6285 | 0.0000 | |
| GSE63941 | STK19 | 8859 | 36019_at | -0.0415 | 0.8446 | |
| GSE77861 | STK19 | 8859 | 36019_at | -0.4359 | 0.0095 | |
| GSE97050 | STK19 | A_21_P0013130 | -0.3154 | 0.2276 | ||
| SRP007169 | STK19 | 8859 | RNAseq | -2.3655 | 0.0000 | |
| SRP008496 | STK19 | 8859 | RNAseq | -2.1541 | 0.0000 | |
| SRP064894 | STK19 | 8859 | RNAseq | 0.1858 | 0.4909 | |
| SRP133303 | STK19 | 8859 | RNAseq | -0.6462 | 0.0001 | |
| SRP159526 | STK19 | 8859 | RNAseq | -0.5706 | 0.0753 | |
| SRP193095 | STK19 | 8859 | RNAseq | -0.7901 | 0.0000 | |
| SRP219564 | STK19 | 8859 | RNAseq | -0.2019 | 0.3738 | |
| TCGA | STK19 | 8859 | RNAseq | -0.1053 | 0.1389 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by STK19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK19 | 8859 | 5 | 1 | 24 | |
| GSE20123 | STK19 | 8859 | 5 | 1 | 24 | |
| GSE43470 | STK19 | 8859 | 5 | 1 | 37 | |
| GSE46452 | STK19 | 8859 | 1 | 10 | 48 | |
| GSE47630 | STK19 | 8859 | 7 | 4 | 29 | |
| GSE54993 | STK19 | 8859 | 2 | 1 | 67 | |
| GSE54994 | STK19 | 8859 | 11 | 4 | 38 | |
| GSE60625 | STK19 | 8859 | 0 | 1 | 10 | |
| GSE74703 | STK19 | 8859 | 5 | 0 | 31 | |
| GSE74704 | STK19 | 8859 | 2 | 0 | 18 | |
| TCGA | STK19 | 8859 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of STK19:
Generating mutation plots.
Highly correlated genes for STK19:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK19 | CLTA | 0.751274 | 3 | 0 | 3 |
| STK19 | RNF103 | 0.734824 | 3 | 0 | 3 |
| STK19 | FAM172A | 0.734074 | 4 | 0 | 4 |
| STK19 | BRK1 | 0.731695 | 5 | 0 | 5 |
| STK19 | UFC1 | 0.719591 | 6 | 0 | 5 |
| STK19 | CD2BP2 | 0.713866 | 3 | 0 | 3 |
| STK19 | TMEM220 | 0.71363 | 4 | 0 | 4 |
| STK19 | UBE2R2 | 0.712756 | 5 | 0 | 5 |
| STK19 | KDM5D | 0.710821 | 4 | 0 | 4 |
| STK19 | ZNF548 | 0.708353 | 3 | 0 | 3 |
| STK19 | EIF1AY | 0.699922 | 4 | 0 | 4 |
| STK19 | NSA2 | 0.695054 | 4 | 0 | 3 |
| STK19 | ZNF681 | 0.694306 | 4 | 0 | 3 |
| STK19 | SH3BP5 | 0.69341 | 5 | 0 | 4 |
| STK19 | JAK2 | 0.693276 | 7 | 0 | 6 |
| STK19 | DCTN3 | 0.692361 | 9 | 0 | 8 |
| STK19 | ZNF829 | 0.691959 | 4 | 0 | 4 |
| STK19 | ATP6V1D | 0.689362 | 7 | 0 | 7 |
| STK19 | TRIM23 | 0.687704 | 3 | 0 | 3 |
| STK19 | NKAPL | 0.687156 | 5 | 0 | 3 |
For details and further investigation, click here
