SEC14L5

 

Full name: SEC14 like lipid binding 5 Alias Symbol: KIAA0420|PRELID4B
Type: protein-coding gene Cytoband: 16p13.3
Entrez ID: 9717 HGNC ID: HGNC:29032 Ensembl Gene: ENSG00000103184 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SEC14L5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SEC14L5 9717 210169_at -0.2799 0.2830
GSE20347 SEC14L5 9717 210169_at -0.0548 0.5692
GSE23400 SEC14L5 9717 210169_at -0.1465 0.0002
GSE26886 SEC14L5 9717 210169_at -0.6165 0.0003
GSE29001 SEC14L5 9717 210169_at -0.6902 0.0034
GSE38129 SEC14L5 9717 210169_at -0.2739 0.0048
GSE45670 SEC14L5 9717 210169_at -0.1167 0.4381
GSE53622 SEC14L5 9717 42372 -0.6562 0.0000
GSE53624 SEC14L5 9717 42372 -0.8495 0.0000
GSE63941 SEC14L5 9717 210169_at -0.0298 0.9152
GSE77861 SEC14L5 9717 210169_at -0.0815 0.3598
SRP064894 SEC14L5 9717 RNAseq -1.1874 0.0000
SRP133303 SEC14L5 9717 RNAseq -0.2854 0.1649
SRP159526 SEC14L5 9717 RNAseq -0.7419 0.2451
SRP193095 SEC14L5 9717 RNAseq -0.3723 0.0287
SRP219564 SEC14L5 9717 RNAseq -0.7271 0.0731
TCGA SEC14L5 9717 RNAseq -1.3389 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by SEC14L5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SEC14L5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SEC14L5 9717 6 4 20
GSE20123 SEC14L5 9717 6 3 21
GSE43470 SEC14L5 9717 4 4 35
GSE46452 SEC14L5 9717 38 1 20
GSE47630 SEC14L5 9717 13 6 21
GSE54993 SEC14L5 9717 3 5 62
GSE54994 SEC14L5 9717 5 9 39
GSE60625 SEC14L5 9717 4 0 7
GSE74703 SEC14L5 9717 4 4 28
GSE74704 SEC14L5 9717 3 2 15
TCGA SEC14L5 9717 19 13 64

Total number of gains: 105; Total number of losses: 51; Total Number of normals: 332.  


 

Somatic mutations of SEC14L5:

 

Generating mutation plots.

 

Highly correlated genes for SEC14L5:

 

Showing top 20/330 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SEC14L5ATP6V0D10.705074303
SEC14L5LINC003170.68795303
SEC14L5LINC006610.679291303
SEC14L5ZMAT20.671727303
SEC14L5HIPK10.665512403
SEC14L5CLVS10.652916303
SEC14L5HNF1A0.641879303
SEC14L5TMEM2420.637534303
SEC14L5UBE2D20.637493303
SEC14L5HHLA10.635642303
SEC14L5CAPNS20.629501403
SEC14L5DSC20.627624404
SEC14L5C16orf720.620877303
SEC14L5PRDM20.617721303
SEC14L5ARL2BP0.61725403
SEC14L5TSSK20.612096504
SEC14L5IL90.611695303
SEC14L5PIM10.607534504
SEC14L5PKN20.605856303
SEC14L5ENHO0.601638303

For details and further investigation, click here