| Full name: serpin family A member 12 | Alias Symbol: OL-64|Vaspin | ||
| Type: protein-coding gene | Cytoband: 14q32.13 | ||
| Entrez ID: 145264 | HGNC ID: HGNC:18359 | Ensembl Gene: ENSG00000165953 | OMIM ID: 617471 |
| Drug and gene relationship at DGIdb | |||
Expression of SERPINA12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINA12 | 145264 | 1552544_at | -0.0379 | 0.8944 | |
| GSE26886 | SERPINA12 | 145264 | 1552544_at | 0.1036 | 0.4037 | |
| GSE45670 | SERPINA12 | 145264 | 1552544_at | 0.1093 | 0.2881 | |
| GSE53622 | SERPINA12 | 145264 | 18681 | 0.3021 | 0.1436 | |
| GSE53624 | SERPINA12 | 145264 | 18681 | 0.2795 | 0.0950 | |
| GSE63941 | SERPINA12 | 145264 | 1552544_at | -0.0094 | 0.9545 | |
| GSE77861 | SERPINA12 | 145264 | 1552544_at | 0.0031 | 0.9774 | |
| GSE97050 | SERPINA12 | 145264 | A_23_P88177 | 0.0530 | 0.8094 | |
| TCGA | SERPINA12 | 145264 | RNAseq | 3.6742 | 0.0080 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SERPINA12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINA12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINA12 | 145264 | 10 | 4 | 16 | |
| GSE20123 | SERPINA12 | 145264 | 10 | 3 | 17 | |
| GSE43470 | SERPINA12 | 145264 | 7 | 3 | 33 | |
| GSE46452 | SERPINA12 | 145264 | 16 | 3 | 40 | |
| GSE47630 | SERPINA12 | 145264 | 11 | 8 | 21 | |
| GSE54993 | SERPINA12 | 145264 | 3 | 8 | 59 | |
| GSE54994 | SERPINA12 | 145264 | 21 | 4 | 28 | |
| GSE60625 | SERPINA12 | 145264 | 0 | 2 | 9 | |
| GSE74703 | SERPINA12 | 145264 | 6 | 3 | 27 | |
| GSE74704 | SERPINA12 | 145264 | 6 | 3 | 11 | |
| TCGA | SERPINA12 | 145264 | 30 | 20 | 46 |
Total number of gains: 120; Total number of losses: 61; Total Number of normals: 307.
Somatic mutations of SERPINA12:
Generating mutation plots.
Highly correlated genes for SERPINA12:
Showing top 20/28 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINA12 | IQCG | 0.734987 | 3 | 0 | 3 |
| SERPINA12 | ATG13 | 0.707617 | 3 | 0 | 3 |
| SERPINA12 | DYRK4 | 0.684044 | 3 | 0 | 3 |
| SERPINA12 | DIRC1 | 0.680307 | 3 | 0 | 3 |
| SERPINA12 | KCND1 | 0.679925 | 3 | 0 | 3 |
| SERPINA12 | CXCR5 | 0.67385 | 3 | 0 | 3 |
| SERPINA12 | TNFRSF4 | 0.666188 | 3 | 0 | 3 |
| SERPINA12 | NLRC4 | 0.663977 | 3 | 0 | 3 |
| SERPINA12 | GPRIN3 | 0.656099 | 3 | 0 | 3 |
| SERPINA12 | DEFA4 | 0.649192 | 3 | 0 | 3 |
| SERPINA12 | TNFRSF1A | 0.645917 | 3 | 0 | 3 |
| SERPINA12 | SRSF12 | 0.63956 | 3 | 0 | 3 |
| SERPINA12 | LAMP2 | 0.63238 | 3 | 0 | 3 |
| SERPINA12 | DOC2B | 0.598642 | 3 | 0 | 3 |
| SERPINA12 | IL2RA | 0.598248 | 3 | 0 | 3 |
| SERPINA12 | KIR2DL5A | 0.590358 | 3 | 0 | 3 |
| SERPINA12 | DNAH17-AS1 | 0.584448 | 3 | 0 | 3 |
| SERPINA12 | GRIP2 | 0.583642 | 3 | 0 | 3 |
| SERPINA12 | ZIC5 | 0.570077 | 3 | 0 | 3 |
| SERPINA12 | ETV5 | 0.569157 | 4 | 0 | 3 |
For details and further investigation, click here
