| Full name: mannosidase alpha class 1B member 1 | Alias Symbol: MANA-ER|MRT15|ERManI | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 11253 | HGNC ID: HGNC:6823 | Ensembl Gene: ENSG00000177239 | OMIM ID: 604346 |
| Drug and gene relationship at DGIdb | |||
Expression of MAN1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAN1B1 | 11253 | 218636_s_at | 0.2324 | 0.5361 | |
| GSE20347 | MAN1B1 | 11253 | 218636_s_at | 0.1305 | 0.1758 | |
| GSE23400 | MAN1B1 | 11253 | 218636_s_at | 0.2559 | 0.0003 | |
| GSE26886 | MAN1B1 | 11253 | 218636_s_at | 0.4045 | 0.0291 | |
| GSE29001 | MAN1B1 | 11253 | 218636_s_at | 0.1006 | 0.7562 | |
| GSE38129 | MAN1B1 | 11253 | 218636_s_at | 0.2783 | 0.0012 | |
| GSE45670 | MAN1B1 | 11253 | 218636_s_at | 0.2736 | 0.0312 | |
| GSE53622 | MAN1B1 | 11253 | 118762 | 0.6023 | 0.0000 | |
| GSE53624 | MAN1B1 | 11253 | 34298 | 0.5398 | 0.0000 | |
| GSE63941 | MAN1B1 | 11253 | 218636_s_at | -0.5454 | 0.1162 | |
| GSE77861 | MAN1B1 | 11253 | 218636_s_at | 0.0984 | 0.4875 | |
| GSE97050 | MAN1B1 | 11253 | A_33_P3299796 | -0.0653 | 0.8078 | |
| SRP007169 | MAN1B1 | 11253 | RNAseq | 0.0643 | 0.8657 | |
| SRP008496 | MAN1B1 | 11253 | RNAseq | 0.1005 | 0.7319 | |
| SRP064894 | MAN1B1 | 11253 | RNAseq | 0.9646 | 0.0010 | |
| SRP133303 | MAN1B1 | 11253 | RNAseq | 0.3585 | 0.0876 | |
| SRP159526 | MAN1B1 | 11253 | RNAseq | 0.5234 | 0.0875 | |
| SRP193095 | MAN1B1 | 11253 | RNAseq | 0.2750 | 0.0009 | |
| SRP219564 | MAN1B1 | 11253 | RNAseq | 0.6182 | 0.0392 | |
| TCGA | MAN1B1 | 11253 | RNAseq | 0.1415 | 0.0087 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAN1B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAN1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAN1B1 | 11253 | 5 | 7 | 18 | |
| GSE20123 | MAN1B1 | 11253 | 5 | 7 | 18 | |
| GSE43470 | MAN1B1 | 11253 | 3 | 7 | 33 | |
| GSE46452 | MAN1B1 | 11253 | 6 | 13 | 40 | |
| GSE47630 | MAN1B1 | 11253 | 6 | 15 | 19 | |
| GSE54993 | MAN1B1 | 11253 | 3 | 3 | 64 | |
| GSE54994 | MAN1B1 | 11253 | 12 | 8 | 33 | |
| GSE60625 | MAN1B1 | 11253 | 0 | 0 | 11 | |
| GSE74703 | MAN1B1 | 11253 | 3 | 5 | 28 | |
| GSE74704 | MAN1B1 | 11253 | 3 | 5 | 12 | |
| TCGA | MAN1B1 | 11253 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of MAN1B1:
Generating mutation plots.
Highly correlated genes for MAN1B1:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAN1B1 | TP53I11 | 0.764129 | 3 | 0 | 3 |
| MAN1B1 | LENG8 | 0.754582 | 3 | 0 | 3 |
| MAN1B1 | SETD5 | 0.75385 | 3 | 0 | 3 |
| MAN1B1 | FAM193A | 0.728561 | 4 | 0 | 4 |
| MAN1B1 | INO80 | 0.724126 | 3 | 0 | 3 |
| MAN1B1 | MCM3AP | 0.716395 | 4 | 0 | 3 |
| MAN1B1 | SCMH1 | 0.708701 | 3 | 0 | 3 |
| MAN1B1 | RAB1B | 0.701504 | 3 | 0 | 3 |
| MAN1B1 | ASB1 | 0.696653 | 3 | 0 | 3 |
| MAN1B1 | GP1BA | 0.695227 | 3 | 0 | 3 |
| MAN1B1 | UBASH3A | 0.693415 | 3 | 0 | 3 |
| MAN1B1 | SLC10A3 | 0.692217 | 4 | 0 | 3 |
| MAN1B1 | RIMS2 | 0.692203 | 4 | 0 | 3 |
| MAN1B1 | PDGFB | 0.687063 | 3 | 0 | 3 |
| MAN1B1 | ANKRD11 | 0.686392 | 3 | 0 | 3 |
| MAN1B1 | UTP23 | 0.685326 | 4 | 0 | 4 |
| MAN1B1 | SURF4 | 0.684188 | 5 | 0 | 5 |
| MAN1B1 | ZNF789 | 0.683999 | 3 | 0 | 3 |
| MAN1B1 | KDM4A | 0.677408 | 4 | 0 | 3 |
| MAN1B1 | CISD2 | 0.67522 | 3 | 0 | 3 |
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