UTP6

 

Full name: UTP6 small subunit processome component Alias Symbol: HCA66
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 55813 HGNC ID: HGNC:18279 Ensembl Gene: ENSG00000108651 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of UTP6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UTP6 55813 218715_at 0.4667 0.0591
GSE20347 UTP6 55813 218715_at 0.6185 0.0019
GSE23400 UTP6 55813 218715_at 0.5788 0.0000
GSE26886 UTP6 55813 218715_at 0.6955 0.0002
GSE29001 UTP6 55813 218715_at 0.4743 0.0386
GSE38129 UTP6 55813 218715_at 0.7299 0.0000
GSE45670 UTP6 55813 218715_at 0.4767 0.0011
GSE53622 UTP6 55813 51595 0.2272 0.0001
GSE53624 UTP6 55813 51595 0.4199 0.0000
GSE63941 UTP6 55813 218715_at 0.3063 0.4086
GSE77861 UTP6 55813 218715_at 0.7313 0.0006
GSE97050 UTP6 55813 A_23_P164237 0.3344 0.3074
SRP007169 UTP6 55813 RNAseq 0.7557 0.0518
SRP008496 UTP6 55813 RNAseq 0.5434 0.0422
SRP064894 UTP6 55813 RNAseq 0.4834 0.0002
SRP133303 UTP6 55813 RNAseq 0.3044 0.0080
SRP159526 UTP6 55813 RNAseq 0.1997 0.2776
SRP193095 UTP6 55813 RNAseq 0.2190 0.0108
SRP219564 UTP6 55813 RNAseq 0.2010 0.4411
TCGA UTP6 55813 RNAseq 0.1796 0.0006

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UTP6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UTP6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UTP6 55813 9 2 19
GSE20123 UTP6 55813 8 2 20
GSE43470 UTP6 55813 1 1 41
GSE46452 UTP6 55813 33 1 25
GSE47630 UTP6 55813 7 1 32
GSE54993 UTP6 55813 2 3 65
GSE54994 UTP6 55813 7 6 40
GSE60625 UTP6 55813 4 0 7
GSE74703 UTP6 55813 1 1 34
GSE74704 UTP6 55813 6 2 12
TCGA UTP6 55813 20 10 66

Total number of gains: 98; Total number of losses: 29; Total Number of normals: 361.  

 

Somatic mutations of UTP6:

 

Generating mutation plots.

 

Highly correlated genes for UTP6:

 

Showing top 20/1943 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UTP6SFR10.76326303
UTP6EME10.743355505
UTP6ZNF7780.737677303
UTP6BIRC30.726483303
UTP6DHX330.7151807
UTP6AATF0.71397912012
UTP6ALS20.711734606
UTP6CIAO10.711224505
UTP6MTERF30.707313807
UTP6EBNA1BP20.706089303
UTP6COPRS0.705919504
UTP6PSMD110.70190611010
UTP6DDX39A0.70070212011
UTP6PTRH20.69770613012
UTP6USP320.6972403
UTP6CCDC860.696784908
UTP6MRPL360.695117505
UTP6CDCA20.694686504
UTP6EFTUD20.693941908
UTP6OCIAD20.693761605

For details and further investigation, click here