CEP152

 

Full name: centrosomal protein 152 Alias Symbol: KIAA0912|SCKL5|MCPH9
Type: protein-coding gene Cytoband: 15q21.1
Entrez ID: 22995 HGNC ID: HGNC:29298 Ensembl Gene: ENSG00000103995 OMIM ID: 613529
Drug and gene relationship at DGIdb

 

Expression of CEP152:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CEP152 22995 239413_at 0.1374 0.7856
GSE20347 CEP152 22995 215170_s_at 0.4048 0.0017
GSE23400 CEP152 22995 215882_at 0.1362 0.0000
GSE26886 CEP152 22995 239413_at 0.0097 0.9827
GSE29001 CEP152 22995 215170_s_at 0.5723 0.0639
GSE38129 CEP152 22995 215170_s_at 0.4830 0.0005
GSE45670 CEP152 22995 239413_at 0.4453 0.0787
GSE53622 CEP152 22995 12446 0.7716 0.0000
GSE53624 CEP152 22995 12446 0.9885 0.0000
GSE63941 CEP152 22995 239413_at 0.4139 0.4909
GSE77861 CEP152 22995 239413_at 1.1862 0.0153
GSE97050 CEP152 22995 A_24_P652700 0.2793 0.2569
SRP007169 CEP152 22995 RNAseq 1.9695 0.0000
SRP008496 CEP152 22995 RNAseq 1.5563 0.0000
SRP064894 CEP152 22995 RNAseq 0.4403 0.1543
SRP133303 CEP152 22995 RNAseq 0.7091 0.0027
SRP159526 CEP152 22995 RNAseq 0.6580 0.0407
SRP193095 CEP152 22995 RNAseq 0.6230 0.0000
SRP219564 CEP152 22995 RNAseq 0.4090 0.2119
TCGA CEP152 22995 RNAseq 0.3519 0.0001

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by CEP152 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CEP152:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CEP152 22995 5 3 22
GSE20123 CEP152 22995 5 3 22
GSE43470 CEP152 22995 5 4 34
GSE46452 CEP152 22995 3 7 49
GSE47630 CEP152 22995 8 10 22
GSE54993 CEP152 22995 4 6 60
GSE54994 CEP152 22995 5 7 41
GSE60625 CEP152 22995 4 0 7
GSE74703 CEP152 22995 5 3 28
GSE74704 CEP152 22995 2 3 15
TCGA CEP152 22995 10 18 68

Total number of gains: 56; Total number of losses: 64; Total Number of normals: 368.  


 

Somatic mutations of CEP152:

 

Generating mutation plots.

 

Highly correlated genes for CEP152:

 

Showing top 20/909 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CEP152SFR10.770001303
CEP152TCTEX1D20.753069303
CEP152SPSB20.742221303
CEP152KLHL50.727433303
CEP152PHF5A0.725428404
CEP152HSPA130.725003303
CEP152MMS22L0.72342303
CEP152PIF10.719614706
CEP152DHX370.718666303
CEP152CALCRL0.717287303
CEP152MAP3K130.711866404
CEP152LRRC340.708864303
CEP152DDX210.70696303
CEP152FLVCR10.704298505
CEP152PSMG30.70204303
CEP152TMEM1380.699687404
CEP152ANGEL20.698823404
CEP152ZNF2600.696505303
CEP152PIK3R30.692303
CEP152PTCD10.691702303

For details and further investigation, click here