| Full name: chromosome 8 open reading frame 58 | Alias Symbol: FLJ34715 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 541565 | HGNC ID: HGNC:32233 | Ensembl Gene: ENSG00000241852 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C8orf58:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C8orf58 | 541565 | 227263_at | 0.3989 | 0.4440 | |
| GSE26886 | C8orf58 | 541565 | 236296_x_at | 0.1846 | 0.1270 | |
| GSE45670 | C8orf58 | 541565 | 227263_at | 0.0359 | 0.8579 | |
| GSE53622 | C8orf58 | 541565 | 80833 | -0.5550 | 0.0000 | |
| GSE53624 | C8orf58 | 541565 | 80833 | -0.4400 | 0.0000 | |
| GSE63941 | C8orf58 | 541565 | 236296_x_at | -0.0063 | 0.9735 | |
| GSE77861 | C8orf58 | 541565 | 227263_at | 0.3827 | 0.1473 | |
| GSE97050 | C8orf58 | 541565 | A_33_P3410849 | -0.3238 | 0.2252 | |
| SRP007169 | C8orf58 | 541565 | RNAseq | 0.0986 | 0.8181 | |
| SRP008496 | C8orf58 | 541565 | RNAseq | 0.3249 | 0.3312 | |
| SRP064894 | C8orf58 | 541565 | RNAseq | 0.0855 | 0.6612 | |
| SRP133303 | C8orf58 | 541565 | RNAseq | -0.2257 | 0.4536 | |
| SRP159526 | C8orf58 | 541565 | RNAseq | 0.0292 | 0.9486 | |
| SRP193095 | C8orf58 | 541565 | RNAseq | 0.4761 | 0.0055 | |
| SRP219564 | C8orf58 | 541565 | RNAseq | -0.0199 | 0.9441 | |
| TCGA | C8orf58 | 541565 | RNAseq | 0.1660 | 0.0541 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C8orf58 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C8orf58:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C8orf58 | 541565 | 4 | 10 | 16 | |
| GSE20123 | C8orf58 | 541565 | 4 | 10 | 16 | |
| GSE43470 | C8orf58 | 541565 | 4 | 9 | 30 | |
| GSE46452 | C8orf58 | 541565 | 13 | 13 | 33 | |
| GSE47630 | C8orf58 | 541565 | 10 | 8 | 22 | |
| GSE54993 | C8orf58 | 541565 | 2 | 14 | 54 | |
| GSE54994 | C8orf58 | 541565 | 10 | 17 | 26 | |
| GSE60625 | C8orf58 | 541565 | 3 | 0 | 8 | |
| GSE74703 | C8orf58 | 541565 | 4 | 7 | 25 | |
| GSE74704 | C8orf58 | 541565 | 3 | 7 | 10 | |
| TCGA | C8orf58 | 541565 | 14 | 43 | 39 |
Total number of gains: 71; Total number of losses: 138; Total Number of normals: 279.
Somatic mutations of C8orf58:
Generating mutation plots.
Highly correlated genes for C8orf58:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C8orf58 | CCL16 | 0.741057 | 3 | 0 | 3 |
| C8orf58 | TMEM174 | 0.705594 | 3 | 0 | 3 |
| C8orf58 | VMAC | 0.698705 | 3 | 0 | 3 |
| C8orf58 | BPTF | 0.696357 | 3 | 0 | 3 |
| C8orf58 | MOG | 0.681763 | 4 | 0 | 3 |
| C8orf58 | TBCE | 0.677131 | 3 | 0 | 3 |
| C8orf58 | TGIF1 | 0.671071 | 3 | 0 | 3 |
| C8orf58 | ALDH4A1 | 0.662131 | 3 | 0 | 3 |
| C8orf58 | USP2 | 0.642193 | 3 | 0 | 3 |
| C8orf58 | DUSP8 | 0.637311 | 3 | 0 | 3 |
| C8orf58 | DMTN | 0.624729 | 3 | 0 | 3 |
| C8orf58 | SLC9A1 | 0.610208 | 3 | 0 | 3 |
| C8orf58 | SFXN5 | 0.609594 | 4 | 0 | 3 |
| C8orf58 | KRT81 | 0.606607 | 5 | 0 | 4 |
| C8orf58 | HMHB1 | 0.605701 | 4 | 0 | 3 |
| C8orf58 | ARHGAP4 | 0.602315 | 4 | 0 | 4 |
| C8orf58 | SOX17 | 0.600399 | 4 | 0 | 3 |
| C8orf58 | GNAT1 | 0.599409 | 3 | 0 | 3 |
| C8orf58 | GPR153 | 0.591303 | 4 | 0 | 3 |
| C8orf58 | PSD | 0.589619 | 4 | 0 | 4 |
For details and further investigation, click here
