| Full name: small G protein signaling modulator 1 | Alias Symbol: KIAA1941 | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 129049 | HGNC ID: HGNC:29410 | Ensembl Gene: ENSG00000167037 | OMIM ID: 611417 |
| Drug and gene relationship at DGIdb | |||
Expression of SGSM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SGSM1 | 129049 | 1562239_at | -0.0341 | 0.9351 | |
| GSE26886 | SGSM1 | 129049 | 242921_at | 0.1197 | 0.3713 | |
| GSE45670 | SGSM1 | 129049 | 242921_at | 0.1364 | 0.1460 | |
| GSE53622 | SGSM1 | 129049 | 9780 | -0.7882 | 0.0000 | |
| GSE53624 | SGSM1 | 129049 | 9780 | -0.2064 | 0.2205 | |
| GSE63941 | SGSM1 | 129049 | 242921_at | 0.3553 | 0.0274 | |
| GSE77861 | SGSM1 | 129049 | 242921_at | -0.0454 | 0.5863 | |
| GSE97050 | SGSM1 | 129049 | A_32_P527371 | -0.3986 | 0.3791 | |
| SRP064894 | SGSM1 | 129049 | RNAseq | -0.8465 | 0.0043 | |
| SRP133303 | SGSM1 | 129049 | RNAseq | -0.8083 | 0.0004 | |
| SRP159526 | SGSM1 | 129049 | RNAseq | -0.3174 | 0.4126 | |
| SRP193095 | SGSM1 | 129049 | RNAseq | -0.7293 | 0.0258 | |
| SRP219564 | SGSM1 | 129049 | RNAseq | -0.2025 | 0.7456 | |
| TCGA | SGSM1 | 129049 | RNAseq | -1.7553 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SGSM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SGSM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SGSM1 | 129049 | 5 | 7 | 18 | |
| GSE20123 | SGSM1 | 129049 | 5 | 6 | 19 | |
| GSE43470 | SGSM1 | 129049 | 3 | 5 | 35 | |
| GSE46452 | SGSM1 | 129049 | 32 | 1 | 26 | |
| GSE47630 | SGSM1 | 129049 | 8 | 5 | 27 | |
| GSE54993 | SGSM1 | 129049 | 3 | 6 | 61 | |
| GSE54994 | SGSM1 | 129049 | 11 | 7 | 35 | |
| GSE60625 | SGSM1 | 129049 | 5 | 0 | 6 | |
| GSE74703 | SGSM1 | 129049 | 3 | 4 | 29 | |
| GSE74704 | SGSM1 | 129049 | 2 | 3 | 15 | |
| TCGA | SGSM1 | 129049 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 59; Total Number of normals: 326.
Somatic mutations of SGSM1:
Generating mutation plots.
Highly correlated genes for SGSM1:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SGSM1 | SLC29A1 | 0.675398 | 3 | 0 | 3 |
| SGSM1 | FNDC9 | 0.659409 | 3 | 0 | 3 |
| SGSM1 | NEUROD6 | 0.648132 | 3 | 0 | 3 |
| SGSM1 | HOXB-AS3 | 0.645026 | 3 | 0 | 3 |
| SGSM1 | IQSEC2 | 0.630667 | 3 | 0 | 3 |
| SGSM1 | PRB1 | 0.626966 | 4 | 0 | 3 |
| SGSM1 | C10orf90 | 0.622182 | 3 | 0 | 3 |
| SGSM1 | KRTAP3-1 | 0.618544 | 3 | 0 | 3 |
| SGSM1 | APOB | 0.615189 | 3 | 0 | 3 |
| SGSM1 | ABCA4 | 0.615006 | 3 | 0 | 3 |
| SGSM1 | ZSCAN16-AS1 | 0.613175 | 3 | 0 | 3 |
| SGSM1 | TRIM10 | 0.608666 | 4 | 0 | 3 |
| SGSM1 | PRB4 | 0.60677 | 4 | 0 | 3 |
| SGSM1 | PKD2L1 | 0.60303 | 3 | 0 | 3 |
| SGSM1 | LMX1A | 0.60156 | 4 | 0 | 3 |
| SGSM1 | DCST1 | 0.601303 | 4 | 0 | 3 |
| SGSM1 | ATP2A1 | 0.596103 | 3 | 0 | 3 |
| SGSM1 | SIRT3 | 0.593786 | 4 | 0 | 3 |
| SGSM1 | MAPK15 | 0.591883 | 3 | 0 | 3 |
| SGSM1 | PHKG1 | 0.588459 | 4 | 0 | 3 |
For details and further investigation, click here
