| Full name: SH3 binding domain protein 5 like | Alias Symbol: KIAA1720 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 80851 | HGNC ID: HGNC:29360 | Ensembl Gene: ENSG00000175137 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SH3BP5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3BP5L | 80851 | 223265_at | 0.5013 | 0.0900 | |
| GSE26886 | SH3BP5L | 80851 | 223265_at | -0.2088 | 0.0966 | |
| GSE45670 | SH3BP5L | 80851 | 223265_at | 0.1159 | 0.3129 | |
| GSE53622 | SH3BP5L | 80851 | 6694 | -0.5040 | 0.0000 | |
| GSE53624 | SH3BP5L | 80851 | 6694 | -0.3886 | 0.0000 | |
| GSE63941 | SH3BP5L | 80851 | 223265_at | -0.1590 | 0.7047 | |
| GSE77861 | SH3BP5L | 80851 | 223265_at | -0.1479 | 0.3441 | |
| GSE97050 | SH3BP5L | 80851 | A_23_P426989 | -0.2355 | 0.2773 | |
| SRP007169 | SH3BP5L | 80851 | RNAseq | -1.9775 | 0.0001 | |
| SRP008496 | SH3BP5L | 80851 | RNAseq | -1.7994 | 0.0000 | |
| SRP064894 | SH3BP5L | 80851 | RNAseq | -0.7898 | 0.0000 | |
| SRP133303 | SH3BP5L | 80851 | RNAseq | -0.3158 | 0.0710 | |
| SRP159526 | SH3BP5L | 80851 | RNAseq | -0.5466 | 0.0929 | |
| SRP193095 | SH3BP5L | 80851 | RNAseq | -0.3475 | 0.0131 | |
| SRP219564 | SH3BP5L | 80851 | RNAseq | -0.7546 | 0.0245 | |
| TCGA | SH3BP5L | 80851 | RNAseq | 0.0392 | 0.4770 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SH3BP5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3BP5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3BP5L | 80851 | 8 | 1 | 21 | |
| GSE20123 | SH3BP5L | 80851 | 7 | 1 | 22 | |
| GSE43470 | SH3BP5L | 80851 | 4 | 3 | 36 | |
| GSE46452 | SH3BP5L | 80851 | 4 | 2 | 53 | |
| GSE47630 | SH3BP5L | 80851 | 15 | 1 | 24 | |
| GSE54993 | SH3BP5L | 80851 | 0 | 6 | 64 | |
| GSE54994 | SH3BP5L | 80851 | 18 | 0 | 35 | |
| GSE60625 | SH3BP5L | 80851 | 0 | 0 | 11 | |
| GSE74703 | SH3BP5L | 80851 | 4 | 1 | 31 | |
| GSE74704 | SH3BP5L | 80851 | 2 | 0 | 18 | |
| TCGA | SH3BP5L | 80851 | 45 | 4 | 47 |
Total number of gains: 107; Total number of losses: 19; Total Number of normals: 362.
Somatic mutations of SH3BP5L:
Generating mutation plots.
Highly correlated genes for SH3BP5L:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3BP5L | USP21 | 0.701616 | 3 | 0 | 3 |
| SH3BP5L | FOXP4 | 0.681454 | 3 | 0 | 3 |
| SH3BP5L | HNRNPUL1 | 0.655928 | 3 | 0 | 3 |
| SH3BP5L | MAVS | 0.65401 | 3 | 0 | 3 |
| SH3BP5L | ZNF473 | 0.653758 | 3 | 0 | 3 |
| SH3BP5L | ZNF408 | 0.653113 | 3 | 0 | 3 |
| SH3BP5L | ADAM15 | 0.652125 | 4 | 0 | 4 |
| SH3BP5L | DGCR2 | 0.651088 | 5 | 0 | 4 |
| SH3BP5L | RNF187 | 0.650947 | 3 | 0 | 3 |
| SH3BP5L | ARHGAP35 | 0.650607 | 3 | 0 | 3 |
| SH3BP5L | PEPD | 0.648319 | 3 | 0 | 3 |
| SH3BP5L | MSL2 | 0.644609 | 3 | 0 | 3 |
| SH3BP5L | NUCB1 | 0.643537 | 3 | 0 | 3 |
| SH3BP5L | C2orf49 | 0.642237 | 3 | 0 | 3 |
| SH3BP5L | IL34 | 0.636984 | 4 | 0 | 3 |
| SH3BP5L | ZBTB42 | 0.633768 | 4 | 0 | 3 |
| SH3BP5L | RPRD2 | 0.633558 | 3 | 0 | 3 |
| SH3BP5L | RRAGC | 0.631143 | 3 | 0 | 3 |
| SH3BP5L | HNRNPAB | 0.627688 | 3 | 0 | 3 |
| SH3BP5L | C1orf159 | 0.627239 | 3 | 0 | 3 |
For details and further investigation, click here
