| Full name: shisa family member 6 | Alias Symbol: FLJ45455 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 388336 | HGNC ID: HGNC:34491 | Ensembl Gene: ENSG00000188803 | OMIM ID: 617327 |
| Drug and gene relationship at DGIdb | |||
Expression of SHISA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHISA6 | 388336 | 229266_at | -0.3378 | 0.3793 | |
| GSE45670 | SHISA6 | 388336 | 229266_at | 0.0564 | 0.9395 | |
| GSE53622 | SHISA6 | 388336 | 33755 | 0.1372 | 0.4382 | |
| GSE53624 | SHISA6 | 388336 | 33755 | 0.7254 | 0.0000 | |
| GSE97050 | SHISA6 | 388336 | A_33_P3326217 | -0.0283 | 0.9547 | |
| SRP133303 | SHISA6 | 388336 | RNAseq | -0.5250 | 0.3067 | |
| SRP159526 | SHISA6 | 388336 | RNAseq | 2.2773 | 0.0212 | |
| TCGA | SHISA6 | 388336 | RNAseq | -1.2158 | 0.0528 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SHISA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHISA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHISA6 | 388336 | 3 | 4 | 23 | |
| GSE20123 | SHISA6 | 388336 | 3 | 5 | 22 | |
| GSE43470 | SHISA6 | 388336 | 2 | 6 | 35 | |
| GSE46452 | SHISA6 | 388336 | 34 | 1 | 24 | |
| GSE47630 | SHISA6 | 388336 | 7 | 1 | 32 | |
| GSE54993 | SHISA6 | 388336 | 3 | 3 | 64 | |
| GSE54994 | SHISA6 | 388336 | 6 | 6 | 41 | |
| GSE60625 | SHISA6 | 388336 | 4 | 0 | 7 | |
| GSE74703 | SHISA6 | 388336 | 2 | 4 | 30 | |
| GSE74704 | SHISA6 | 388336 | 2 | 2 | 16 | |
| TCGA | SHISA6 | 388336 | 18 | 21 | 57 |
Total number of gains: 84; Total number of losses: 53; Total Number of normals: 351.
Somatic mutations of SHISA6:
Generating mutation plots.
Highly correlated genes for SHISA6:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHISA6 | GKAP1 | 0.816176 | 3 | 0 | 3 |
| SHISA6 | ANKDD1A | 0.705172 | 3 | 0 | 3 |
| SHISA6 | SHC2 | 0.70064 | 3 | 0 | 3 |
| SHISA6 | ZNF428 | 0.697451 | 3 | 0 | 3 |
| SHISA6 | GNAZ | 0.674134 | 4 | 0 | 3 |
| SHISA6 | GPR88 | 0.669823 | 4 | 0 | 3 |
| SHISA6 | KCNF1 | 0.668624 | 4 | 0 | 3 |
| SHISA6 | RPRM | 0.664661 | 4 | 0 | 3 |
| SHISA6 | NISCH | 0.655458 | 3 | 0 | 3 |
| SHISA6 | ULK2 | 0.645859 | 3 | 0 | 3 |
| SHISA6 | EBF4 | 0.633349 | 4 | 0 | 3 |
| SHISA6 | SNAP91 | 0.619712 | 5 | 0 | 3 |
| SHISA6 | NTNG2 | 0.611435 | 3 | 0 | 3 |
| SHISA6 | DNAI1 | 0.6033 | 3 | 0 | 3 |
| SHISA6 | WDR6 | 0.602336 | 3 | 0 | 3 |
| SHISA6 | FAM181A | 0.599472 | 3 | 0 | 3 |
| SHISA6 | HRH2 | 0.590175 | 3 | 0 | 3 |
| SHISA6 | WFDC3 | 0.589778 | 3 | 0 | 3 |
| SHISA6 | CHST10 | 0.586364 | 4 | 0 | 3 |
| SHISA6 | SLC22A17 | 0.579606 | 3 | 0 | 3 |
For details and further investigation, click here
