| Full name: Ski2 like RNA helicase | Alias Symbol: HLP|DDX13|SKI2W|170A|SKIV2L1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 6499 | HGNC ID: HGNC:10898 | Ensembl Gene: ENSG00000204351 | OMIM ID: 600478 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SKIV2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SKIV2L | 6499 | 203727_at | 0.6070 | 0.1672 | |
| GSE20347 | SKIV2L | 6499 | 203727_at | 0.1859 | 0.0243 | |
| GSE23400 | SKIV2L | 6499 | 203727_at | 0.1211 | 0.0172 | |
| GSE26886 | SKIV2L | 6499 | 203727_at | -0.0980 | 0.5565 | |
| GSE29001 | SKIV2L | 6499 | 203727_at | 0.1774 | 0.4186 | |
| GSE38129 | SKIV2L | 6499 | 203727_at | 0.2410 | 0.0003 | |
| GSE45670 | SKIV2L | 6499 | 203727_at | 0.5291 | 0.0000 | |
| GSE53622 | SKIV2L | 6499 | 7229 | 0.1211 | 0.0846 | |
| GSE53624 | SKIV2L | 6499 | 7229 | 0.4046 | 0.0000 | |
| GSE63941 | SKIV2L | 6499 | 203727_at | -0.2939 | 0.2384 | |
| GSE77861 | SKIV2L | 6499 | 203727_at | 0.1215 | 0.2928 | |
| GSE97050 | SKIV2L | 6499 | A_23_P168080 | -0.0885 | 0.7743 | |
| SRP007169 | SKIV2L | 6499 | RNAseq | -0.1902 | 0.5370 | |
| SRP008496 | SKIV2L | 6499 | RNAseq | -0.4304 | 0.0234 | |
| SRP064894 | SKIV2L | 6499 | RNAseq | 0.7052 | 0.0000 | |
| SRP133303 | SKIV2L | 6499 | RNAseq | 0.0287 | 0.8100 | |
| SRP159526 | SKIV2L | 6499 | RNAseq | 0.2132 | 0.2735 | |
| SRP193095 | SKIV2L | 6499 | RNAseq | 0.2876 | 0.0056 | |
| SRP219564 | SKIV2L | 6499 | RNAseq | 0.3236 | 0.0907 | |
| TCGA | SKIV2L | 6499 | RNAseq | 0.0167 | 0.7322 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SKIV2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SKIV2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SKIV2L | 6499 | 5 | 1 | 24 | |
| GSE20123 | SKIV2L | 6499 | 5 | 1 | 24 | |
| GSE43470 | SKIV2L | 6499 | 5 | 1 | 37 | |
| GSE46452 | SKIV2L | 6499 | 1 | 10 | 48 | |
| GSE47630 | SKIV2L | 6499 | 7 | 4 | 29 | |
| GSE54993 | SKIV2L | 6499 | 2 | 1 | 67 | |
| GSE54994 | SKIV2L | 6499 | 11 | 4 | 38 | |
| GSE60625 | SKIV2L | 6499 | 0 | 1 | 10 | |
| GSE74703 | SKIV2L | 6499 | 5 | 0 | 31 | |
| GSE74704 | SKIV2L | 6499 | 2 | 0 | 18 | |
| TCGA | SKIV2L | 6499 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of SKIV2L:
Generating mutation plots.
Highly correlated genes for SKIV2L:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SKIV2L | AP2A1 | 0.718668 | 3 | 0 | 3 |
| SKIV2L | SEC61A2 | 0.676063 | 4 | 0 | 4 |
| SKIV2L | MRPL14 | 0.658709 | 6 | 0 | 4 |
| SKIV2L | TMEM63B | 0.65699 | 5 | 0 | 4 |
| SKIV2L | GPATCH4 | 0.656221 | 4 | 0 | 4 |
| SKIV2L | SLC39A3 | 0.651371 | 3 | 0 | 3 |
| SKIV2L | RAC3 | 0.645269 | 5 | 0 | 4 |
| SKIV2L | ARHGEF19 | 0.642867 | 3 | 0 | 3 |
| SKIV2L | RRP36 | 0.635559 | 6 | 0 | 6 |
| SKIV2L | NCAPH2 | 0.625661 | 4 | 0 | 4 |
| SKIV2L | ABCA7 | 0.623691 | 4 | 0 | 3 |
| SKIV2L | ZNF445 | 0.617849 | 3 | 0 | 3 |
| SKIV2L | RPL7L1 | 0.615377 | 4 | 0 | 3 |
| SKIV2L | CLPTM1L | 0.61325 | 4 | 0 | 4 |
| SKIV2L | CCDC167 | 0.612868 | 6 | 0 | 5 |
| SKIV2L | WDR24 | 0.612669 | 4 | 0 | 3 |
| SKIV2L | RNF2 | 0.612025 | 4 | 0 | 3 |
| SKIV2L | INTS1 | 0.611945 | 10 | 0 | 9 |
| SKIV2L | SRC | 0.611084 | 5 | 0 | 4 |
| SKIV2L | ZFP41 | 0.60651 | 3 | 0 | 3 |
For details and further investigation, click here
