| Full name: Ral GTPase activating protein catalytic alpha subunit 2 | Alias Symbol: dJ1049G11.4|AS250|KIAA1272|RapGAPalpha2 | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 57186 | HGNC ID: HGNC:16207 | Ensembl Gene: ENSG00000188559 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RALGAPA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RALGAPA2 | 57186 | 225499_at | 0.6813 | 0.2792 | |
| GSE26886 | RALGAPA2 | 57186 | 225499_at | 0.2503 | 0.3610 | |
| GSE45670 | RALGAPA2 | 57186 | 225499_at | -0.0267 | 0.9146 | |
| GSE53622 | RALGAPA2 | 57186 | 14020 | -0.6312 | 0.0000 | |
| GSE53624 | RALGAPA2 | 57186 | 4388 | -0.4275 | 0.0000 | |
| GSE63941 | RALGAPA2 | 57186 | 225499_at | 1.5471 | 0.0385 | |
| GSE77861 | RALGAPA2 | 57186 | 225499_at | -0.1118 | 0.6867 | |
| GSE97050 | RALGAPA2 | 57186 | A_33_P3470781 | 0.4065 | 0.4000 | |
| SRP007169 | RALGAPA2 | 57186 | RNAseq | -0.8532 | 0.0069 | |
| SRP008496 | RALGAPA2 | 57186 | RNAseq | -0.3348 | 0.2399 | |
| SRP064894 | RALGAPA2 | 57186 | RNAseq | -0.1062 | 0.6010 | |
| SRP133303 | RALGAPA2 | 57186 | RNAseq | -0.4999 | 0.0031 | |
| SRP159526 | RALGAPA2 | 57186 | RNAseq | -0.1759 | 0.4933 | |
| SRP193095 | RALGAPA2 | 57186 | RNAseq | -0.0484 | 0.8545 | |
| SRP219564 | RALGAPA2 | 57186 | RNAseq | -0.2546 | 0.4642 | |
| TCGA | RALGAPA2 | 57186 | RNAseq | -0.5965 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RALGAPA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RALGAPA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RALGAPA2 | 57186 | 13 | 2 | 15 | |
| GSE20123 | RALGAPA2 | 57186 | 13 | 2 | 15 | |
| GSE43470 | RALGAPA2 | 57186 | 11 | 1 | 31 | |
| GSE46452 | RALGAPA2 | 57186 | 27 | 1 | 31 | |
| GSE47630 | RALGAPA2 | 57186 | 17 | 4 | 19 | |
| GSE54993 | RALGAPA2 | 57186 | 0 | 15 | 55 | |
| GSE54994 | RALGAPA2 | 57186 | 27 | 2 | 24 | |
| GSE60625 | RALGAPA2 | 57186 | 0 | 0 | 11 | |
| GSE74703 | RALGAPA2 | 57186 | 8 | 1 | 27 | |
| GSE74704 | RALGAPA2 | 57186 | 7 | 2 | 11 | |
| TCGA | RALGAPA2 | 57186 | 43 | 11 | 42 |
Total number of gains: 166; Total number of losses: 41; Total Number of normals: 281.
Somatic mutations of RALGAPA2:
Generating mutation plots.
Highly correlated genes for RALGAPA2:
Showing top 20/228 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RALGAPA2 | ABHD12 | 0.7908 | 3 | 0 | 3 |
| RALGAPA2 | RNF114 | 0.789113 | 3 | 0 | 3 |
| RALGAPA2 | TNK1 | 0.766542 | 3 | 0 | 3 |
| RALGAPA2 | PPP1R3D | 0.760273 | 3 | 0 | 3 |
| RALGAPA2 | ZXDC | 0.752487 | 3 | 0 | 3 |
| RALGAPA2 | MTHFSD | 0.750369 | 3 | 0 | 3 |
| RALGAPA2 | CHD4 | 0.750227 | 3 | 0 | 3 |
| RALGAPA2 | FLOT2 | 0.73248 | 3 | 0 | 3 |
| RALGAPA2 | HNRNPUL1 | 0.732424 | 3 | 0 | 3 |
| RALGAPA2 | PRRC2C | 0.729625 | 3 | 0 | 3 |
| RALGAPA2 | DROSHA | 0.729517 | 3 | 0 | 3 |
| RALGAPA2 | LMLN | 0.719258 | 3 | 0 | 3 |
| RALGAPA2 | MMP15 | 0.717485 | 3 | 0 | 3 |
| RALGAPA2 | SLC25A40 | 0.717206 | 3 | 0 | 3 |
| RALGAPA2 | TNFRSF9 | 0.714972 | 3 | 0 | 3 |
| RALGAPA2 | NAT10 | 0.71034 | 3 | 0 | 3 |
| RALGAPA2 | NCSTN | 0.706297 | 3 | 0 | 3 |
| RALGAPA2 | DHRS13 | 0.706238 | 3 | 0 | 3 |
| RALGAPA2 | PPARA | 0.705328 | 3 | 0 | 3 |
| RALGAPA2 | GBP2 | 0.703609 | 3 | 0 | 3 |
For details and further investigation, click here
