| Full name: ubiquitin specific peptidase 48 | Alias Symbol: FLJ23277|FLJ11328|FLJ20103|FLJ23054|MGC14879 | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 84196 | HGNC ID: HGNC:18533 | Ensembl Gene: ENSG00000090686 | OMIM ID: 617445 |
| Drug and gene relationship at DGIdb | |||
Expression of USP48:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP48 | 84196 | 220079_s_at | 0.1356 | 0.7345 | |
| GSE20347 | USP48 | 84196 | 220079_s_at | -0.3098 | 0.0211 | |
| GSE23400 | USP48 | 84196 | 220079_s_at | 0.0594 | 0.4449 | |
| GSE26886 | USP48 | 84196 | 220079_s_at | 0.5696 | 0.1024 | |
| GSE29001 | USP48 | 84196 | 220079_s_at | -0.0265 | 0.9328 | |
| GSE38129 | USP48 | 84196 | 220079_s_at | -0.3869 | 0.0014 | |
| GSE45670 | USP48 | 84196 | 225925_s_at | 0.1295 | 0.3323 | |
| GSE53622 | USP48 | 84196 | 9773 | -0.0384 | 0.5791 | |
| GSE53624 | USP48 | 84196 | 9773 | -0.0052 | 0.9221 | |
| GSE63941 | USP48 | 84196 | 220079_s_at | -0.5290 | 0.3317 | |
| GSE77861 | USP48 | 84196 | 220079_s_at | -0.3528 | 0.3107 | |
| GSE97050 | USP48 | 84196 | A_23_P200551 | -0.0091 | 0.9726 | |
| SRP007169 | USP48 | 84196 | RNAseq | 0.9824 | 0.0285 | |
| SRP008496 | USP48 | 84196 | RNAseq | 1.1444 | 0.0010 | |
| SRP064894 | USP48 | 84196 | RNAseq | 0.0830 | 0.5691 | |
| SRP133303 | USP48 | 84196 | RNAseq | 0.0887 | 0.5098 | |
| SRP159526 | USP48 | 84196 | RNAseq | 0.0001 | 0.9996 | |
| SRP193095 | USP48 | 84196 | RNAseq | -0.1209 | 0.1552 | |
| SRP219564 | USP48 | 84196 | RNAseq | -0.1839 | 0.4197 | |
| TCGA | USP48 | 84196 | RNAseq | -0.0757 | 0.1037 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by USP48 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP48:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP48 | 84196 | 0 | 5 | 25 | |
| GSE20123 | USP48 | 84196 | 0 | 4 | 26 | |
| GSE43470 | USP48 | 84196 | 2 | 6 | 35 | |
| GSE46452 | USP48 | 84196 | 5 | 1 | 53 | |
| GSE47630 | USP48 | 84196 | 8 | 3 | 29 | |
| GSE54993 | USP48 | 84196 | 3 | 1 | 66 | |
| GSE54994 | USP48 | 84196 | 11 | 6 | 36 | |
| GSE60625 | USP48 | 84196 | 0 | 0 | 11 | |
| GSE74703 | USP48 | 84196 | 1 | 4 | 31 | |
| GSE74704 | USP48 | 84196 | 0 | 0 | 20 | |
| TCGA | USP48 | 84196 | 9 | 23 | 64 |
Total number of gains: 39; Total number of losses: 53; Total Number of normals: 396.
Somatic mutations of USP48:
Generating mutation plots.
Highly correlated genes for USP48:
Showing top 20/279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP48 | RICTOR | 0.763987 | 3 | 0 | 3 |
| USP48 | SRSF6 | 0.758336 | 3 | 0 | 3 |
| USP48 | RHOC | 0.733617 | 3 | 0 | 3 |
| USP48 | ZBTB44 | 0.729519 | 4 | 0 | 3 |
| USP48 | RFNG | 0.727757 | 4 | 0 | 4 |
| USP48 | TBC1D25 | 0.722911 | 3 | 0 | 3 |
| USP48 | TNPO3 | 0.721383 | 3 | 0 | 3 |
| USP48 | FAM122B | 0.719824 | 3 | 0 | 3 |
| USP48 | SLC44A4 | 0.714464 | 3 | 0 | 3 |
| USP48 | NFXL1 | 0.707696 | 3 | 0 | 3 |
| USP48 | THAP5 | 0.707302 | 3 | 0 | 3 |
| USP48 | DHFR | 0.706392 | 3 | 0 | 3 |
| USP48 | PFDN5 | 0.704463 | 3 | 0 | 3 |
| USP48 | SLC25A29 | 0.703828 | 4 | 0 | 4 |
| USP48 | OXCT1 | 0.703324 | 4 | 0 | 4 |
| USP48 | METTL23 | 0.703032 | 3 | 0 | 3 |
| USP48 | LHX5 | 0.694406 | 3 | 0 | 3 |
| USP48 | ZNF704 | 0.694368 | 3 | 0 | 3 |
| USP48 | SATB1 | 0.689373 | 3 | 0 | 3 |
| USP48 | LINC00623 | 0.682878 | 3 | 0 | 3 |
For details and further investigation, click here
