| Full name: transcription factor 25 | Alias Symbol: Nulp1|KIAA1049 | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 22980 | HGNC ID: HGNC:29181 | Ensembl Gene: ENSG00000141002 | OMIM ID: 612326 |
| Drug and gene relationship at DGIdb | |||
Expression of TCF25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCF25 | 22980 | 221495_s_at | 0.1054 | 0.6977 | |
| GSE20347 | TCF25 | 22980 | 213311_s_at | 0.0291 | 0.8578 | |
| GSE23400 | TCF25 | 22980 | 221495_s_at | -0.1729 | 0.0063 | |
| GSE26886 | TCF25 | 22980 | 221495_s_at | 0.1386 | 0.3440 | |
| GSE29001 | TCF25 | 22980 | 213311_s_at | -0.1615 | 0.7669 | |
| GSE38129 | TCF25 | 22980 | 213311_s_at | -0.0343 | 0.7592 | |
| GSE45670 | TCF25 | 22980 | 221495_s_at | -0.2367 | 0.0274 | |
| GSE53622 | TCF25 | 22980 | 32241 | -0.3413 | 0.0000 | |
| GSE53624 | TCF25 | 22980 | 32241 | -0.2416 | 0.0000 | |
| GSE63941 | TCF25 | 22980 | 213311_s_at | -1.2137 | 0.0325 | |
| GSE77861 | TCF25 | 22980 | 221495_s_at | -0.1567 | 0.3799 | |
| GSE97050 | TCF25 | 22980 | A_24_P306561 | -0.0572 | 0.7982 | |
| SRP007169 | TCF25 | 22980 | RNAseq | -1.2779 | 0.0001 | |
| SRP008496 | TCF25 | 22980 | RNAseq | -1.2728 | 0.0000 | |
| SRP064894 | TCF25 | 22980 | RNAseq | -0.0551 | 0.7925 | |
| SRP133303 | TCF25 | 22980 | RNAseq | 0.0166 | 0.9205 | |
| SRP159526 | TCF25 | 22980 | RNAseq | -0.1618 | 0.6143 | |
| SRP193095 | TCF25 | 22980 | RNAseq | -0.0626 | 0.5807 | |
| SRP219564 | TCF25 | 22980 | RNAseq | -0.1186 | 0.6674 | |
| TCGA | TCF25 | 22980 | RNAseq | -0.1439 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TCF25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCF25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCF25 | 22980 | 4 | 3 | 23 | |
| GSE20123 | TCF25 | 22980 | 4 | 3 | 23 | |
| GSE43470 | TCF25 | 22980 | 1 | 13 | 29 | |
| GSE46452 | TCF25 | 22980 | 38 | 1 | 20 | |
| GSE47630 | TCF25 | 22980 | 11 | 9 | 20 | |
| GSE54993 | TCF25 | 22980 | 3 | 4 | 63 | |
| GSE54994 | TCF25 | 22980 | 9 | 11 | 33 | |
| GSE60625 | TCF25 | 22980 | 4 | 0 | 7 | |
| GSE74703 | TCF25 | 22980 | 1 | 9 | 26 | |
| GSE74704 | TCF25 | 22980 | 3 | 1 | 16 | |
| TCGA | TCF25 | 22980 | 26 | 15 | 55 |
Total number of gains: 104; Total number of losses: 69; Total Number of normals: 315.
Somatic mutations of TCF25:
Generating mutation plots.
Highly correlated genes for TCF25:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCF25 | ZNF595 | 0.785685 | 3 | 0 | 3 |
| TCF25 | CD200 | 0.762806 | 3 | 0 | 3 |
| TCF25 | TPSG1 | 0.747268 | 3 | 0 | 3 |
| TCF25 | NOTCH4 | 0.744269 | 3 | 0 | 3 |
| TCF25 | TNFRSF9 | 0.738095 | 4 | 0 | 3 |
| TCF25 | ETS1 | 0.71898 | 3 | 0 | 3 |
| TCF25 | PDZD11 | 0.7138 | 3 | 0 | 3 |
| TCF25 | ADAM19 | 0.712865 | 3 | 0 | 3 |
| TCF25 | PPP1R37 | 0.708852 | 3 | 0 | 3 |
| TCF25 | SEMA6A | 0.701777 | 3 | 0 | 3 |
| TCF25 | DGKD | 0.696885 | 3 | 0 | 3 |
| TCF25 | S1PR1 | 0.691687 | 3 | 0 | 3 |
| TCF25 | FGFR1 | 0.68875 | 3 | 0 | 3 |
| TCF25 | SLC44A4 | 0.687005 | 3 | 0 | 3 |
| TCF25 | IL18BP | 0.683979 | 3 | 0 | 3 |
| TCF25 | NKG7 | 0.6838 | 3 | 0 | 3 |
| TCF25 | VSTM4 | 0.683107 | 3 | 0 | 3 |
| TCF25 | VPS28 | 0.682415 | 4 | 0 | 4 |
| TCF25 | ORMDL3 | 0.681702 | 3 | 0 | 3 |
| TCF25 | LRRC17 | 0.67885 | 3 | 0 | 3 |
For details and further investigation, click here
