SLC47A1

 

Full name: solute carrier family 47 member 1 Alias Symbol: FLJ10847|MATE1
Type: protein-coding gene Cytoband: 17p11.2
Entrez ID: 55244 HGNC ID: HGNC:25588 Ensembl Gene: ENSG00000142494 OMIM ID: 609832
Drug and gene relationship at DGIdb

 

Expression of SLC47A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC47A1 55244 219525_at 0.0350 0.9779
GSE20347 SLC47A1 55244 219525_at 0.6152 0.0713
GSE23400 SLC47A1 55244 219525_at 0.1520 0.0478
GSE26886 SLC47A1 55244 219525_at 0.7215 0.1365
GSE29001 SLC47A1 55244 219525_at 0.0424 0.9295
GSE38129 SLC47A1 55244 219525_at 0.8488 0.0028
GSE45670 SLC47A1 55244 219525_at 0.5910 0.2726
GSE53622 SLC47A1 55244 7912 0.6379 0.0000
GSE53624 SLC47A1 55244 7912 0.5591 0.0000
GSE63941 SLC47A1 55244 219525_at -0.6109 0.6494
GSE77861 SLC47A1 55244 219525_at 0.8347 0.1238
GSE97050 SLC47A1 55244 A_33_P3403399 0.1340 0.7701
SRP064894 SLC47A1 55244 RNAseq 0.1047 0.7487
SRP133303 SLC47A1 55244 RNAseq -0.0120 0.9620
SRP159526 SLC47A1 55244 RNAseq 1.5339 0.0055
SRP193095 SLC47A1 55244 RNAseq 0.4663 0.0464
SRP219564 SLC47A1 55244 RNAseq 1.2267 0.0388
TCGA SLC47A1 55244 RNAseq 1.6020 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by SLC47A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC47A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC47A1 55244 4 3 23
GSE20123 SLC47A1 55244 4 4 22
GSE43470 SLC47A1 55244 1 5 37
GSE46452 SLC47A1 55244 34 1 24
GSE47630 SLC47A1 55244 7 1 32
GSE54993 SLC47A1 55244 3 3 64
GSE54994 SLC47A1 55244 7 6 40
GSE60625 SLC47A1 55244 4 0 7
GSE74703 SLC47A1 55244 1 2 33
GSE74704 SLC47A1 55244 3 1 16
TCGA SLC47A1 55244 19 24 53

Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.  

 

Somatic mutations of SLC47A1:

 

Generating mutation plots.

 

Highly correlated genes for SLC47A1:

 

Showing top 20/124 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC47A1C17orf1000.677941303
SLC47A1CLSTN20.668766303
SLC47A1STK32B0.656857303
SLC47A1AK80.640766303
SLC47A1PCYT1A0.630497505
SLC47A1MSI20.619391403
SLC47A1TMTC10.618271505
SLC47A1GOSR10.60999303
SLC47A1PIGS0.609882403
SLC47A1SORL10.608957303
SLC47A1COA60.599162504
SLC47A1NQO10.598512504
SLC47A1CAPRIN20.598221403
SLC47A1ADAM230.5949321108
SLC47A1IRS20.59469504
SLC47A1FREM20.593944604
SLC47A1DLX6-AS10.593724403
SLC47A1MRAP20.588092804
SLC47A1SOX50.58795503
SLC47A1SRXN10.585432605

For details and further investigation, click here