| Full name: melanocortin 2 receptor accessory protein 2 | Alias Symbol: bA51G5.2 | ||
| Type: protein-coding gene | Cytoband: 6q14.2 | ||
| Entrez ID: 112609 | HGNC ID: HGNC:21232 | Ensembl Gene: ENSG00000135324 | OMIM ID: 615410 |
| Drug and gene relationship at DGIdb | |||
Expression of MRAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRAP2 | 112609 | 227226_at | -0.2460 | 0.8774 | |
| GSE26886 | MRAP2 | 112609 | 227226_at | 1.0747 | 0.0581 | |
| GSE45670 | MRAP2 | 112609 | 227226_at | 0.4924 | 0.4606 | |
| GSE53622 | MRAP2 | 112609 | 16993 | 0.0629 | 0.8420 | |
| GSE53624 | MRAP2 | 112609 | 16993 | 0.4011 | 0.0616 | |
| GSE63941 | MRAP2 | 112609 | 227226_at | 0.0616 | 0.9030 | |
| GSE77861 | MRAP2 | 112609 | 227226_at | 0.8423 | 0.1272 | |
| GSE97050 | MRAP2 | 112609 | A_23_P357207 | 0.0051 | 0.9903 | |
| SRP007169 | MRAP2 | 112609 | RNAseq | 3.4074 | 0.0000 | |
| SRP008496 | MRAP2 | 112609 | RNAseq | 3.0258 | 0.0000 | |
| SRP064894 | MRAP2 | 112609 | RNAseq | -0.2471 | 0.6241 | |
| SRP133303 | MRAP2 | 112609 | RNAseq | 0.5796 | 0.1715 | |
| SRP159526 | MRAP2 | 112609 | RNAseq | 1.9408 | 0.0019 | |
| SRP193095 | MRAP2 | 112609 | RNAseq | -0.1981 | 0.5664 | |
| SRP219564 | MRAP2 | 112609 | RNAseq | 0.7340 | 0.4847 | |
| TCGA | MRAP2 | 112609 | RNAseq | -0.1172 | 0.7168 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MRAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRAP2 | 112609 | 1 | 4 | 25 | |
| GSE20123 | MRAP2 | 112609 | 1 | 3 | 26 | |
| GSE43470 | MRAP2 | 112609 | 2 | 1 | 40 | |
| GSE46452 | MRAP2 | 112609 | 2 | 11 | 46 | |
| GSE47630 | MRAP2 | 112609 | 8 | 6 | 26 | |
| GSE54993 | MRAP2 | 112609 | 3 | 2 | 65 | |
| GSE54994 | MRAP2 | 112609 | 8 | 8 | 37 | |
| GSE60625 | MRAP2 | 112609 | 0 | 1 | 10 | |
| GSE74703 | MRAP2 | 112609 | 2 | 1 | 33 | |
| GSE74704 | MRAP2 | 112609 | 0 | 2 | 18 | |
| TCGA | MRAP2 | 112609 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 60; Total Number of normals: 395.
Somatic mutations of MRAP2:
Generating mutation plots.
Highly correlated genes for MRAP2:
Showing top 20/86 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRAP2 | BDNF | 0.715362 | 4 | 0 | 4 |
| MRAP2 | SOX2-OT | 0.665672 | 6 | 0 | 5 |
| MRAP2 | VTCN1 | 0.662826 | 5 | 0 | 3 |
| MRAP2 | KCNE3 | 0.659935 | 4 | 0 | 4 |
| MRAP2 | MSI2 | 0.656401 | 4 | 0 | 4 |
| MRAP2 | MSL1 | 0.631988 | 3 | 0 | 3 |
| MRAP2 | NTRK2 | 0.629393 | 8 | 0 | 7 |
| MRAP2 | KLHL13 | 0.621287 | 5 | 0 | 4 |
| MRAP2 | SNRNP25 | 0.620652 | 3 | 0 | 3 |
| MRAP2 | KRTCAP3 | 0.620249 | 3 | 0 | 3 |
| MRAP2 | FAXC | 0.619973 | 6 | 0 | 4 |
| MRAP2 | SCN9A | 0.614938 | 5 | 0 | 4 |
| MRAP2 | CYP26A1 | 0.611886 | 7 | 0 | 5 |
| MRAP2 | PRKX | 0.609666 | 5 | 0 | 5 |
| MRAP2 | CYP4F11 | 0.600073 | 5 | 0 | 3 |
| MRAP2 | GSTM4 | 0.597932 | 5 | 0 | 3 |
| MRAP2 | CRMP1 | 0.597885 | 5 | 0 | 4 |
| MRAP2 | SORL1 | 0.595984 | 5 | 0 | 3 |
| MRAP2 | GCNT2 | 0.593962 | 8 | 0 | 7 |
| MRAP2 | CCDC177 | 0.592816 | 4 | 0 | 3 |
For details and further investigation, click here
